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Embryo Gems-3
AUC
21
Anatomy
Graduate
04/06/2011

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Term
Cardiac Looping
Definition
Ventricle and Atrium change positions.

Ventricle move down. Atrium moves up
Term
VSD
Definition
Normally defect in muscular septum
Term
Septum formation in heart
Definition
Endocardial cushion separates atrium from ventricles by forming bicuspid and tricuspid valves.

Primary Septum grows down. Cell death in it forms ostium secundum. Primary septum becomes valve for foramen ovale

Septum secundum grows down to form foramen ovale.
Term
Formation of outflow tract of heart
Definition
Conotruncal septum spirals.

Transposition of great vessels occurs when it fails to spiral.

Tetralogy of Fallot is also due to outflow tract formation. (aorta gets larger segment.)
Term
Seperation of Esophagus/trachea
Definition
Tracheoesophageal ridge divides the two.

Abnormalities;
Fistulas: connection between the two

Atresias: Blind pouch
Term
Omphalacele
Definition
Failure of midgut to retract back into body after herniation caused by growth of liver.

Occurs at umbilical. and intestines are still surronded by amnion
Term
Kidney Formation
Definition
Uteric Bud grows off of mesonephric duct, produces WTI, and grows into metanephric system

WTI induces metanephric mesoderm to form function part of kidneys.

Uteric bud forms collecting ducts
Term
Bladder development
Definition
Urorectal septum Divides cloaca intoanal and genital canal.

Bladder develops partly from allantois.

Urorectal septum becomes the perineum.
Term
Migration of germ cells
Definition
Germ cells migrate from the yolk sac to the genital ridge.

Males: Medulla develops.
Sertoli Cells: produce Anti mullerian hormone.
Leydig cells: Produce dihydrotestosterone

Females: Cortex Develops
Term
Paramesonephric duct and mesonephric duct
Definition
Males: Mesonephric duct forms epididymis, vas deferens. Paramesonephric disapears.

Females: Paramesonephric duct forms uterine tubes and uterus upon merging.
Mesonephric duct dissapears
Term
Fate of:

genital tubercle
Genital Swelling
Urethral folds
Definition
Males:
Genital Tubercle = Glans penis
Urethral folds = Close and form urethra
Genital Swelling = Scrotum

Females:
Genital Tubercle = Clit
Urethral folds = labia minora
Genital swelling = Labia Majora
Term
Aortic Arches
Definition
3: Carotid
4L: Aorta
4R: Subclavian
6: Pulmonary
Term
Neural Crest Defects
Definition
Treacher Collins syndrome

Robin Sequence
Term
Forebrain(prosencephalon)
Definition
Telencephalon: Cerebral Hemispheres

Dicencephalon: Thymus, Hypothalmus, Pituatery, 3rd ventricle.
Term
MidBrain(mesocephalon)
Definition
Mesencephalon:

Anterior(visual)
Posterior (auditory colliculi)

Cerebral aqueduct of slyvius
Term
Hindbrain(rhombencephalon)
Definition
Metencephalon: Cerebellum, Pons

Mylencephalon: Medulla oblongata
Term
Spinal Cord
Definition
Alar Plate: Sensory Neurons. (BMP)

Basal plate: Motor Neurons (SHH)

Mantle Layer: Gray Matter(cell bodies)

Marginal layer: White matter(Fiber tracts)
Term
Eye development
Definition
PAX 6: master gene for development
Term
Synopthalmia and holoprosencephaly
Definition
SHH does not establish the midline and only one eye or cerebral hemisphere is formed.

Also due to altered cholesterol metabolism(Smith-lemli-optiz). SHH rides on cholesterol.

And alcohol
Term
Otic Vessel divdes into
Definition
Term
Otic Vessels Divide into
Definition
Ventral: Saccule and cochlear duct

Dorsal: Utricle, semicircular canal, endolymphatic duct
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