Term
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Definition
Apnea-> mental status changes->coma Sz, miosis, bradycardia, hypotension |
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Term
Complications of EtOH induced chronic liver dz |
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Definition
Bleed d/o, esophageal varices, portosystemic encephalopathy, hepatorenal sx, spontaneous bacterial peritonitis |
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Term
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Definition
Early resp alkalosis-> central resp center shut->metabolic acidosis |
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Term
Clinical presentation of CN poisoning |
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Definition
Agitation, Sz, ↓mental status, resp. depression, brady->tahcy->bradycardia, ↑BP->↓BP, pulmonary eema, bitter almond odor/breath, gastritis, cherry red skin -> cyanosis |
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Term
Poisons that may cause latent GI bleeding |
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Definition
ASA, iron, coumadin, mercuric salts, alkali/acids caustics, lung acting anticoag, rodenticids |
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Term
Toxins cause pulmonary edema |
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Definition
Opioids, ASA, cocaine, ed/hyp, CO, Dig, BB, CCB, chlorine N2O3, organophosphates, ethylene glycol |
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Term
Drugs to avoid in heterocyclic antidepressants tox |
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Definition
Phenytoin (↑ V.ectopy), BB & CCB (↓BP), Ipecac (coma), Type 1A (auinidine, procain) & 1C (flecainide), flumazenil, physostigmine (cardiotoxic, asystole |
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Term
↑anion gap metab acidosis + calcium oxalate crystals in U/A |
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Definition
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Term
Botulism MC initial symptom |
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Definition
Visual disturbance - abducens (VI) n. palsy |
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Term
Antidote for organophosphates (SLUDGE) |
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Definition
❑ Atropine: 2-4 mg IV 5min ❑ 2-PAM if weakness, 25-50 mg/kg/IV up to 1 grm |
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Term
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Definition
physostigmine or pilocarpine |
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Term
Alcohol w/osmolal gap & anion gap |
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Definition
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Term
Sinus brady in a suspected poisoning |
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Definition
Dig, cyanide, organophosphates, carbonates?,βB,CCB |
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Term
Antidote for phenothiazines (neuroleptic durgs w/antiemetic properties and also used in CHF) |
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Definition
❑ Diphenidramine 50mg ❑ Bentropine 2mg IM |
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Term
What med ingestion will cause hypoglycemia |
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Definition
•Oral hypoglycemics •ASA •EtOH •Propranolol |
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Term
Hydrocarbons aspiration hazard depends on 2 physical properties |
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Definition
• Low viscosity (most imp. factor)-measures in SSV (saybolt seconds univ.), ↓# = ↑mortality •high volatility |
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Term
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Definition
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Term
Urine alkalinization indications |
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Definition
•Barb tox •Salicylate (bolus & drip) •TCA •Chloramphenicol |
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Term
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Definition
NON cardio pulmonary edema |
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Term
Blood vs urine alkalinization |
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Definition
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Term
Ethylene glycol & methanol antidote |
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Definition
Ethanol 10%/D5W 800 mg/kg load, then 1-1.5 ml/kg/hr |
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Term
A welder w/fever, shaking chills, salivation, HA, cough, resp distress - Dx? |
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Definition
Metal fume fever - resolves 24-48 hrs |
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Term
What causes metal fume fever |
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Definition
Zinc, copper, Mg, carmium, nickel, brass, Fe, manganesse, tin |
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Term
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Definition
Gastric dilation, ileus, GI hemorrhage, platelet dysfunction |
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Term
Indications for hemodialysis in ASA toxicity |
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Definition
• Levels >90-100mg/dL •CNS depression • Rising levels despite tx • Renal, hepatic or pulm failure • Severe cardiac toxicity • Severe acid/base disturbance |
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Term
Toxidrome of cholinergics |
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Definition
DUMBLES (or SLUDGE): Dirrhea, Urination, Miosis, Bradycardia, Bronchospasms, Bronchorrhea, Lacrimation, Emesis, Salivation, Seizures. Also, coma resp, failure, muscle fasciculation |
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Term
Toxins causing latent HTN |
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Definition
PCP, MAOI, phenylpropanolamine, cacaine, amphetamines |
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Term
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Definition
Valium/Ativam, phenobarbs |
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Term
Rx to avoid in TCA's w/seizures |
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Definition
❑ Dilantin - ↑incidence of dysrhythmias ❑ Romozicin - ↑ seizures risk ❑ Procainamide - worsen quinidine-like tox ❑ Ipecac - rapid onset seizures & coma |
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Term
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Definition
❑ 1/2 awakening dose as load, then 2/3 of awakening dose/hr diluted in D5W or NS |
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Term
Anion gas w/Astra analyzer values |
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Definition
•Normal Astra 7 mEq; ↑AG=>11mEq/L •Normal test = 12; ↑AG >16 |
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Term
EKG changes in poisoned pt |
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Definition
• Prolonged QT • Wide QRS • Sinus brady |
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Term
Opioid intoxications w/out miosis |
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Definition
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Term
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Definition
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Term
Fruit-like breath in poisoning |
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Definition
Nitrites, isopropil alcohol |
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Term
Bitter almonds breath in poisoning |
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Definition
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Term
Pear-like breath in poisoning |
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Definition
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Term
Rotten eggs breath in poisoning |
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Definition
Hydrogen sulfide (used in refineries) |
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Term
Garlic breath in poisoning |
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Definition
Arsenic, phosphorus, organophosphates, tellurium |
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Term
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Definition
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Term
DDx in ↑osmolar gap & normal AG |
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Definition
Ethanol, isopropyl alcohol, glycerol, mannitol, sorbitol, acetone |
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Term
Toxic metabolite of methanol |
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Definition
Formic acid -Blind drunk: produces optic papillitis & retinal edema |
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Term
Fab frag indications in Dig toxicity |
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Definition
V-Fib, V-Tach, sinus brady, resistant to atropine, K+ >5.5, potentially lethal intox |
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Term
What specific lab in a suspected organophosphate exposure |
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Definition
Serum cholinesterase level expected <10% of normal |
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Term
Si/Sx of carboxyhemoglobin |
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Definition
HA, N/A, flu-like, syncope, tachypnea, coma, Sz, CV collapse, resp failure |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
N-acetylcysteine 140 mg/kg, then PO 70 mg/kg q4 hrs x 17 |
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Term
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Definition
Methanol, ethyl alcohol, isopropyl, glycerol, mannitol, ethylene gly, DKA, lactic acidosis |
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Term
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Definition
Methanol, ethyl alcohol, isopropyl, glycerol, mannitol, ethylene gly, DKA, lactic acidosis |
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Term
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Definition
Ethanol, HD, Leukovorin 50 mg IV q 4 hrs x 24 |
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Term
When consider whole bowel irrigation |
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Definition
Lithium, iron, heavy metal, sustained release drugs, body stuffers/packers |
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Term
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Definition
• NAPQI • Metabolized by glutathione |
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Term
Young make with nystagmus & very bizarre, aggressive behavior |
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Definition
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Term
Leading cause of toxin related deaths in USA |
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Definition
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Term
Which poisoning cause latent renal failure |
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Definition
CCl4, mercuric salts, APA, colchicine, ethylene glycol |
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Term
Toxic metabolite of isopropyl alcohol ingestion |
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Definition
Acetone - CNS depre, ↓BP, hemorrhagic gastritis |
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Term
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Definition
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Term
2 MC sympathomimetics toxins |
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Definition
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Term
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Definition
EDTA, calcium disodium edelate |
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Term
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Definition
Steven-Johnson Sx, mucocutaneous membrane bullae |
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Term
CNS complications of opioids |
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Definition
Traumatic mononeuritis - MC painful weakness; Sz, brain abscess, transverse muelitis |
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Term
Activated charcoal not useful in? |
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Definition
Lithium, alkalis, acids, heavy metals, iron |
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Term
What to avoid in organophosphate poisoning |
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Definition
Opioid (↓resp depre), physostigmine, succinyl (prolonged paralysis), sympathomimetics |
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Term
Poisoning assos. w/fever in children |
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Definition
Anticholinergics, ASA, amphetamines, LSD, phenothiazines, TCA |
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Term
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Definition
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Term
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Definition
Macrolide, cipro, cimetidine, alopurinol, propranolol, OCP's |
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Term
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Definition
•Usually elderly •Altered MS • Met acidosis > resp alkalosis •non-cariogenic pulmonary edema |
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Term
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Definition
Deferoxamine 15 mg/kg/hr IV |
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Term
Drugs that ↑1/2 life of phenytoin |
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Definition
Cimetidine, phenothiazine, INH, disulfram, dicumarol, chloramphenicol |
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Term
HD in poisoned pt - indications |
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Definition
Ethylene glycol, EtOH, methanol, lithium w/CNS alteration, ASA if: >100 mg/dL, Sz, CNS changes, evere met acid |
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