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Electrophysiology 1
Chapter Objectives
18
Physiology
Undergraduate 2
12/14/2009

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Term
Name structures of electrical system
Definition
SA Node, internodal tracts (3- PMA), Bachmann's bundle, AV Node, Bundle of His, Right BB, Left BB (anterior and posterior), Purkinje network, fibers
Term
Overall, it takes _____ for the electrical impulse to travel from the SA Node to the Purkinje fibers in the myocardium
Definition
<.20 seconds
Term
Name the 3 parts of the Atrioventricular junction/node-- and which part contains pacemaker cells vs. slows conduction
Definition
Atrionodal region, middle (nodal) region, lowed nodal-His region -- atrionodal and lower nodal-his region contain cells, middle nodal region slows conduction
Term
Name accessory conduction pathways and types/surnames of each
Definition
1. atrioventricular pathways (type A WPW- left posterior atrium, posteroseptal WPW- posterior walls L/R atriums near node, type B WPW- anterior right atrium wall) 2. Atrio-his: aka 'James' fibers: atria-> lower av node/His region 3. nodoventricular/fasciculoventricular: "mahaim fibers": lower av->ventricles, BOHis->ventricles
Term
The ability of cardiac cells to conduct electrical impulses is called:
Definition
property of conductivity
Term
Two basic kinds of cells of the heart and their function:
Definition
Myocardial (contraction/mechanical) cells- contraction and relaxation + specialized cells- generation and conduction of electrical impulses
Term
Contractile protein filaments present in myocardial cells are:
Definition
actin and myosin
Term
The ability of myocardial cells to shorten and return to original length when stimulated by an electrical impulse is:
Definition
property of contractility
Term
Drugs that INCREASE the ability of myocardial contractility are:
Definition
digitalis, sympathomimetics
Term
Drugs that DECREASE the ability of myocardial cells to contract are :
Definition
quinidine, B-blockers, potassium, procainamide
Term
Hypocalcemia decreases/increases the myocardial force of contraction
Definition
decrease
Term
Hypovolemia and anemia decrease/increase force of myocardial contraction:
Definition
increase
Term
Name the three layers of the ventricular walls
Definition
Endocardium, myocardium (muscular layer), epicardium (aka visceral pericardium)
Term
Name the layers of pericardium and its major space/cavity
Definition
visceral pericardium, (pericardial cavity w/ pericardial fluid) and parietal pericardium, *which make up* the serous pericardium, fibrous pericardium
Term
Name and define the 4 properties of cardiac cells:
Definition
(1) Property of conductivity- ability of cells to conduct electrical impulses (ALL) (2) property of contractility- the ability of myocardial cells to shorten and return to normal length (myo only) (3) property of automaticity-ability to spontaneously depolarize w/o external stimulation (pacemaker Only) (4) property o excitability- capability of resting cell to depolarize in response to stimulus
Term
The difference in concentration of ions across the cell membrane at any given time (measured in millivolts)
Definition
electrical potential
Term
All cardiac cells electrical potential @ rest is: ____ except in the ________ where it is ______
Definition
-90mV ; SA and AV nodes ; -70mV
Term
A polarized cardiac cell has _____ on the outside, when depolarized ______. Then comes the period called______, in which potential is ____.
Definition
higher conc. positive; electrical potential has reached 0 mV ; 'the overshoot' ; +20mV
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