Term
| what is the inner membrane of the mitochondria permeable to? |
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Definition
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Term
| what must be actively transported across the inner membrane? |
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Definition
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Term
| in the malate aspartate shuttle, how many ATP are produced by each NADH |
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Definition
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Term
| The glycerophosphate shuttle produces how many ATP per NADH |
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Definition
|
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Term
| when is the glycerphosphate shuttle used? |
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Definition
| to yield additional ATP for brain and skeletal muscle |
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Term
| what is the chemiosmotic hypothesis? |
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Definition
| pumping H+ to the intermembrane space creates an electrochemical and pH gradient that drives ATP synthesis |
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Term
| for each electron pair, how many H+ are pumped into the inter membrane space |
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Definition
|
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Term
| what is standard reduction potential? |
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Definition
| ease with which an electron donor gives up its electrons to an electron acceptor |
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Term
| what is the structure of complex 1 |
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Definition
| 1 FMN iron sulfur clusters |
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Term
| what is the structure of complex 2 |
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Definition
| succinate dehydrogenase, FAD, iron sulfur clusters and cytochrome c |
|
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Term
| what is the function of coenzyme q? |
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Definition
| shuttles electrons b/t 1/2 and 3 |
|
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Term
| what is the structure of complex 3 |
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Definition
| shuttles electrons b/t complexes 3 and 4 |
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Term
| what is the structure of complex 4 |
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Definition
| cytochrome oxidase c- two a hemes and two Cu containing centers. |
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Term
| how many electrons can FAD OR FMN transfer |
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Definition
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Term
| how many protons are pumped from the matirx to the intermembrane space? |
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Definition
|
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Term
| which complex does not pump protons into the intermembrane space |
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Definition
|
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Term
| how is the heme group cofactor |
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Definition
| the heme iron is reduced and oxidized b/t the Fe2 and Fe3+ during electron transport |
|
|
Term
| how many molecules of oxygen does NAD yield? |
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Definition
|
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Term
| what drives ATP synthesis by complex V |
|
Definition
| electrochemical gradient generated by proton translocation |
|
|
Term
| how many protons do complex 3 pump? |
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Definition
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Term
| deprotonation of this causes ATP synthase to spin |
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Definition
| deprotonation of c subunit |
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Term
| rotation of this subunit induces conformational changes in the F1 particle binding site resulting in ATP synthesis |
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Definition
|
|
Term
| what is the function of DNP |
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Definition
| diffuses through membrane and cause electron transport to proceed at a rapid rate w/o establishing a proton gradient. heat is released |
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Term
| what is the name of the uncoupling protein that regulates heat? |
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Definition
|
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Term
|
Definition
| the # of ATPs generated upon electron pair entry at different points |
|
|
Term
| what is the P:O for Complex I? |
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Definition
|
|
Term
| what is the P:O for cytochrome C? |
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Definition
|
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Term
| what can be measured by monitoring oxygen consumption? |
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Definition
| rate of electron transport |
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Term
| What does Rotenone inhibit |
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Definition
|
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Term
| how is the rotenone insecticide overturned |
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Definition
|
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Term
| how is the rotenone insecticide overturned |
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Definition
|
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Term
| what does antimycin inhibit? |
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Definition
|
|
Term
| how is antimycin overturned |
|
Definition
|
|
Term
| how does cyanide and carbon monoxide inhibit complex 4? |
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Definition
|
|
Term
| can cyanide poisoning be overturned? |
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Definition
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|
Term
| can cyanide poisoning be overturned? |
|
Definition
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