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EID
Lecture 1
32
Biology
Undergraduate 4
10/08/2009

Additional Biology Flashcards

 


 

Cards

Term

 

 

 

What are some key questions for the future?

Definition
  • Where will the next new emerging disease come from?
  • How do we apply vaccines effectively?
  • Why are some pathogens highly virulent?
  • Can we identify super spreaders?
Term

 

 

 

Key Quesions for Biologists?

Definition

 

  • Are parasites important in regulating free-living populations?
  • Should we consider parasites part of biodiversity?
  • Is wildlife an important disease resovoir?


Term
Questions that deal with Animals and infectious diseases
Definition
  • Do wild animal diseases provide a good model for humans?
  • Should we reduce animal suffering
  • Should we use parasites as biologocal control agents?
  • Should we reduce parasites in animals released from captivity?
  • Have parasites a conservation value?
Term
Epidemiology
Definition
  • Population dynamics of all infectious diseases(looser definition, not just human diseases)
Term
Epizootology
Definition
The population biology of all other animal diseases, besides human (rarely used)
Term
Parasites
Definition
Now usually called macroparasites, used to be used for worms, fleas, ticks, etc.
Term
Pathogens
Definition
Now called microparasites, traditionally used for viruses and bacteria.
Term
Disease
Definition

Debilitating symptoms caused by parasites.

Often incorrectly used to refer to the agent that causses the disease.

However, infected individuals may not always show symptoms

Term
Infection
Definition
Presence of a pathogen in a host where it may or maynot cause disease.
Term
Pathogenicity/Virulence/Infectiousness
Definition
The extent which a parasite causes disease in its host.
Term
Dynamics
Definition
Changes in parasite abundance in space and time
Term
Epidemic
Definition
A rapid rise in the prevalence or intensity of parasites in humans.
Term
Epizootic
Definition
Rapid rise in the prevalence or intensity of parasites in animals.
Term
Endemic
Definition
Little variation in the prevalence of infection in a population
Term
Prevalence
Definition
Porportion of the host population infected or showing disease syptoms. (usually expressed as a %)
Term
Incidence
Definition
The frequency of new occurences of a disease w/in a defined time interval.
Term
Percentage infected
Definition
The Percentage carrying parasites
Term
Percentage seropositive
Definition
Percentage showing aquired immunity (i.e. % with an aquired immunity)
Term
Intensity (definition: 2-parts)
Definition
Mean number of parasites within infected members of host
Mean number of parasites within all hosts (alternatively used to abundances)
Term
What is Intensity determined by?
Definition

Exposure

Susceptibility

Term
What is Exposure Determined by?
Definition

Density of infective stages

Density of hosts

Term
Susceptibility determied by
Definition
Innate resistance and Aquired resistance
Term
Pathogenicity
Definition
Extent to which a parasite causes disease in its host
Term
Virulence
Definition

The case mortality rate of parasite deaths/infected hosts

The extent to which a pathogen harms its hosts

Term
Immunity
Definition
Ability to combat disease due to the presence of antibodies or activated cells
Term
3 Types Immunity
Definition

Adaptive (aquired)

Innate

Artificial

Term
Adaptive (Aquired) Immunity
Definition
Develops following infection (specfic to strain)
Term
Innate Immunity
Definition
Inherited from parents
Term
Artificial Immunity
Definition
Generated from vaccination
Term
Koch's Postulates
Definition
  • The organism must be detectable at every stage of the disease
  • The organism must be isolated and grown in culture
  • Susceptible animals must be reinfected and show similar characteristics
  • Organism must be reisolated
Term
What did Koch do?
Definition
  • identified pathogens as causitive agents of disease (esp TB)
  • developed staining techniques for bacteria
  • Set out criteria for judging when an organism is cause of disease
  • 1905 Nobel prize
Term
Describe how disease is a dynamic interaction of host, pathogen, and environment.
Definition
  • Pathogen-host:tissue tropism, pathogenicity, immue response, specificity,
  • Host-Environment: nutrition, social status
  • Pathogen-Environment: survival, spatial connection, infectious period, selection

 

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