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Eicosanoid
Eicosanoid Synthesis and Function
7
Biochemistry
Graduate
10/25/2015

Additional Biochemistry Flashcards


 

 


 

Cards

Term

Prostaglandins 

1. Precursor

2. General Function

Definition

1. Cyclooxygenases

 

2. Promote inflammatory responses

Term

Thromboxanes

1. Precursor

2. General Function

Definition

1. Cyclooxygenases

 

2. Important mediators of platelet aggregation

Term

Leukotrienes


1. Precursor

 

2. General Function

Definition

1. Lipoxygenases

 

General Function

1. Smooth muscle contraction 

2. Immediate hypersensisty reactions 

Term

HETEs

 

1. Precursor

 

2. General Function 

Definition

 1. Lipoxygenases

 

2. Chemotactic agents

act on neutrophils and eosinophils

Term

PGE2

 

Functions (4)

Definition
  1. Vasodilator, bronchodilator
     
  2. Cytoprotective in GI tract
     
  3. Proinflammatory: Pain, swelling, redness
     
  4. Contracts uterine smooth muscle, active in labor and delivery
Term

PGF2α

Functions (3)

Definition
  1. Vasoconstrictor
  2. Bronchoconstrictor
  3. Pathogenic in asthma
Term

Prostacyclin (PGI2)



Functions (2)

Produced by?

Definition
1. Vasodilator, Bronchodilator
2. Stabilizes platelets, disaggregates platelets

Produced by blood vessel wall
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