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EEB2245 Exam 3
W Exam 3
195
Biology
Undergraduate 4
04/01/2012

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Term
Micro evolution
Definition
Changes in the genetic composition of a population over time
Term
Population
Definition
A group of individuals belonging to one species, living in a particular area.
Term
Deme
Definition
A subpopulation of individuals who are freely inbreeding, often very homogeneous
Term
Environmental variance
Definition
Non-genetic variation of direct responses to the environment in space or time
Term
Developmental noise
Definition
Non-genetic variation of unknown cause.
Term
Maternal effects
Definition
Non-genetic variation induced in the offspring by the mother
Term
Genomic imprinting
Definition
Non-genetic variation caused by certain genes being expressed in a parent-of-origin specific manner.
Term
Fine grained temporal variation
Definition
Variation that is shorter than the expected lifespan, such as wings changing from season to season.
Term
Coarse grained temporal variation
Definition
Variation that is longer than the expected lifespan. Individual experiences only one environmental variant in its range or lifespan
Term
The Norm of Reaction
Definition
Environmental variation quantified is known as _____
Term
Phenotypic Plasticity
Definition
Bristlecone pine on two opposite growing sites will show ______
Term
Only females at extremes, only males 23-24C, and both in between.
Definition
Snapping turtle environmental sex determination.
Term
Mendelian genetic variation
Definition
Individual loci of large effect
Term
Polygenes (genetic variation)
Definition
Multiple loci each of small effect,
which together act quantitatively to express the
phenotype of organisms.
Term
Epistatic interaction
Definition
The non-additive component of genetic variation
Term
Population Genetics
Definition
The study of how the genetic composition of populations
changes over time, that is, how genetic information is
transmitted from populations of parents to populations of
offspring. It builds on a Mendelian foundation.
Term
Change; Constancy
Definition
Population genetics quantifies ______, while
Mendelian genetics documents _______.
Term
2^n (n being number of non-homologous chromosomes)
Definition
Different number of gamete types is: X^y
Term
Number of alleles per locus ; # of non-homologous chromosomes
Definition
In the "r" equation, r = _____ and "n" = ______
Term
Genetic polymorphisms
Definition
Many loci, multiple alleles per locus
Term
(p+q)^2 =1
Definition
binomial expansion
Term
(p+q+r)^2 = 1
Definition
trinomial expansion
Term
Evolution
Definition
The main violation of hardy weinberg equilibrium
Term
haplotypes
Definition
Unique genetic variants
Term
sub-divided populations with low, but consistent gene flow
Definition
Sewall Wright's "Ideal" Population
Term
Genetic drift, founder effect, bottleneck
Definition
3 things affecting population size
Term
Genetic drift, founder effect, bottleneck
Definition
3 things affecting population size
Term
Genetic drift, founder effect, bottleneck
Definition
3 things affecting population size
Term
Point mutations
Definition
Only source of brand new variation in a population
Term
sicke cell anemia
Definition
A single amino acid substitution in a protein (Valine GUA --> Glutamate GAA) ,
from one (out of 438) nucleotide substitutions in
the gene, causes ______
Term
UV light
Definition
An environmental effect on the mutation rate of yeast, as ______ increases, the amount of leucine recombination also increases
Term
Plutonium 228
Definition
In humans, inhalation of _______ caused an increased environmental effect of cancer causing mutation
Term
rapidly reproducing
Definition
So point mutation has little effect on gene frequency except in ______ microorganisms. (short generation time)
Term
Point mutations
Definition
______ ______ are most notable for the origin of genetic novelties.
Term
Gene flow/Migration
Definition
The exchange of genes between populations via the
movement of reproducing individuals
into or out of a population.
Term
Tay-sachs
Definition
Example of gene flow/migration
Term
tay sachs
Definition
_____ is a disease where the recessive allele can not metabolize brain lipids
Term
higher
Definition
The sephardic jews will develop _____ levels of tay sachs compared to the ashkenazi under high levels of gene flow
Term
homogenizes
Definition
Gene flow, if unopposed by other factors, _______
the populations of a species – no matter what model.
Term
Equal Exchange
Definition
In the ____ _____ model, populations gene's converge toward average allele frequencies and they can change rapidly
Term
Isolation by distance
Definition
The ________ model of gene flow looks at populations within a species
Term
F st equation

q= mean frequency of one of the alleles
v = variance among pop's in its frequency
Definition
Equation used in figuring out among-population variance (Sewall Wright)

q= ?
v= ?
Term
Low
Definition
____ values of the F st equation indicated little variation, complete gene flow, young population
Term
High
Definition
_____ values of the F st equation indicated fixed alleles, no gene flow, and strong natural selection
Term
Isolation by distance
Definition
As average distance of gene dispersal
increases, neighborhood size increases, and genetic variation among populations declines.
Term
dispersal ability
Definition
The value of F st depends highly on _______
Term
Alleles must be selectively neutral
Definition
Underlying assumption of sewall wrights F st equation:
Term
Sewall's Ideal Population structure
Definition
A subdivided population with low and consistent gene flow is known as _____
Term
Charactaristics of Sewall Wright's Ideal Population Structure
Definition
Mutants can arise anywhere and get to other populations, local adaptation still possible for higher fitness, and compromise "jack of all trades" genes not necessary
Term
Random Mating, No Input from New Genetic Material, Infinite Population Size, and Equal Reproductive Success of Genotypes
Definition
Assumptions of hardy weinberg equation (4)
Term
1) Genotype's must have identical fitness
2) Mutation rates negligible
3) Migration rates negligible
Definition
Assumptions of using sampling error as a force to explain natural populations (3)
Term
smaller
Definition
All populations are subject to random genetic
drift – but the _____ the population, the
greater the effect.
Term
Genetic drift
Definition
_______ is the null hypothesis for
evolutionary change, and non-adaptive evolution is the result.
Term
initial frequency
Definition
Genetic Drift and Coalescence: One allele will be lost by chance no matter what eventually

That likelihood is the same as
the allele’s _______ in
the the starting population starting population.
Term
1/4*N
Definition
Estimated rates of allele fixation/loss in
number of generations, when both alleles start out
at equal frequencies, i.e.
p = q = 0.50:
_______ per per generation per locus generation per locus
Term
declines
Definition
Genetic Drift and Heterozygousity

H = 2p(1 – p) -- that is, heterozygosity ____ as one of the allele frequencies shifts closer to 1 (and the other moves toward 0).
Term
Natural selection
Definition
______ lowers expected population size by increasing variation in progeny
number (i.e., some couples produce more offspring than others).
Term
1) unequal reproduction rates
2) natural selection
3) inbreedig
4) fluctuations in pop size
Definition
Fluctuations in effective population caused by: (4)
Term
Bottleneck effect
Definition
- Catastrophes cause enormous reductions in pop. size.
• The longer it remains at small size, the more profound
the genetic consequences.
• Sampling error will change allele frequencies wildly.
Term
Younger
Definition
____ groups show progressively more divergence in blood group type due to drift & inbreeding.
Term
rare alleles
Definition
In a bottleneck, ____ from a one or two carriers get established in many direct descendants of those carriers in very small populations and end up getting over-represented
Term
Founder-flush
Definition
Fixation Fixation of unusual gene combinations is a critical part of the ________ model.
Term
Heterozygousity ; mutation
Definition
Under the founder affect ______ does not go down much because of _______
Term
founder effect
Definition
The _______ is effective at giving a rare allele a numerical advantage, by chance
Term
Genetic Drift
Definition
Allele frequencies change, but unpredictably, both in
direction and magnitude.
Term
Genetic Drift
Definition
Populations tend to lose genetic diversity
Term
Genetic Drift
Definition
Small populations lose genetic diversity more rapidly
than large populations.
Term
Genetic Drift
Definition
Populations that start out identical to one another will
tend to become different, even in the absence of
migration.
Term
Genetic Drift
Definition
Population bottlenecks may cause populations to lack
diversity, even if they are currently large.
Term
Unequal reproductive success, aka Natural Selection
Definition
This occurs when reproductive success – i.e.,
contribution to the next generation – differs
between (among) genotypes
Term
Mutation
Definition
_____ is a random process, even if ______ do occur
at predictable rates; and typically slow.
Term
Gene flow
Definition
_____ is just movement of individuals (or gametes),
without regard for suitability of the new alleles to the new
place.
Term
Genetic drift
Definition
_______ (sampling error) is statistically demonstrable
and inevitable, but unpredictable, and its effects are
neutral overall.
Term
Natural selection
Definition
______ is the only evolutionary force that
specifically adapts populations to their immediate
environments.
Term
Darwin
Definition
His chance of a lifetime came in 1831:
the 5-year voyage of the H. M. S.
Beagle, where he was appointed
(through his connections) as
naturalist-on-board.
Term
Wallace
Definition
He formulated the idea of natural selection independently
Term
Patagonia
Definition
Darwin found fossils of strange vertebrates here
Term
Galápagos & New Zealand (giant tortosis, marine iguanas, and darwins finches)
Definition
Darwin learned about island evolution here
Term
Lyell
Definition
Darwin's influental reading Uniformitarianism written by
Term
Malthus
Definition
Darwins influental reading “On the Principles of Population.” written by
Term
Darwins Descent with Modification
Definition
Offspring resemble their parents, but are not identical to them.

Similarly, descendant species resemble the species from which they are derived, but they are
not identical to their ancestors.
Term
Natural selection
Definition
The mechanism for evolutionary change
Term
Descent with modification and natural selection
Definition
Darwins two paths of thought
Term
Natural selection reasoning
Definition
Organisms produce far more offspring each generation than can possibly survive, given limited resources (from Malthus)
Term
natural selection
Definition
______ reduces species variation over time
Term
Natural selection (formal definition) Futyma
Definition
“Any consistent difference in fitness among phenotypically different classes of biological entities.”
Term
Fitness/Reproductive Success
Definition
a biological entity’s average per capita rate of numerical increase in a population
Term
1. probability of surviving to the various reproductive ages
2. average # of offspring produced via female function, and
3. average # of offspring produced via male function.
Definition
Components of fitness (3)
Term
user friendly definition of natural selection
Definition
“The non-random (differential) reproduction of heritable phenotypes or of genotypes
Term
individual organism
Definition
Natural selection can act on genes, individuals, populations, or species – but strongest on the ______, as the embodiment of the phenotype.
Term
statistical
Definition
Natural selection is a ______ phenomenon: having a “fit” genotype is no guarantee of individual success, and a crappy genotype doesn’t necessarily fail.
Term
independently
Definition
Under selection, allele frequencies change _____ at different loci – unlike genetic drift or
gene flow.
Term
s = selection coefficient, w= relative fitness
Definition
s = 1-w ; s & w?
Term
selection
Definition
_____ can change gene frequencies very rapidly (measured as ∆p or ∆q), even when selection coefficients are low (small).
Term
intermediate
Definition
adaptation to the environment will occur much faster if the
allele in question is at ______ frequencies than if is rare.
Term
Very strong selection
Definition
When the allele is rare, it can’t readily invade the population -- ∆p is very small. ______ is necessary.
Term
heterozygosity
Definition
Natural selection points to the critical importance of genetic variability, as measured by ______
Term
narrow-sense
Definition
Type of heritability that acknowledges the disproportionate
importance of additive genetic variation.
Term
large
Definition
With high h2, there is a _____ response to selection.
Term
larger
Definition
The larger the S, the _____ the response to selection.

R=h^2S (response to selection)
Term
Directional selection
Definition
Also known as “classical,” “Darwinian,” and “neoDarwinian” selection
Term
Directional selection
Definition
type of selection that with multiple loci, can show up as anagenesis, or phyletic gradualism
Term
directional
Definition
Anopheles mosquitos and insecticide resistance is an example of _______ selection
Term
directional
Definition
Norway rats in wales and warafarin is an example of ______ selection
Term
Peppered moth
Definition
Example of directional selection at one locus
Term
against
Definition
In the peppered moth, the melanic form was dominant in sooty conditions. Recently, selection has been quite strong _____ the melanic form: calculated as s = 0.05 – 0.20 at various localities.
Term
Brain size (as % body mass) in humans. It has been increasing over time
Definition
Example of directional selection at many loci
Term
Cline
Definition
_____ in allele frequency: stepped (m = 0), steep, or gradual (m = 1.0). Width of cline actually represents a balance
between gene flow and selection.
Term
ap94 (non-adaptive gene flow due to larval dispersal in the sea) (more ap94 as you get further out into the ocean)
Definition
In mussels, we see an increased intracellular amino acids due to ____ maintaining osmotic balance in salt water.
Term
Stabilizing selection
Definition
Survival of the ordinary, or selection against phenodeviants.
Term
normalizing selection
Definition
Selection where eliminatino of phenodeviants reduces genetic variation
Term
canalizing selection
Definition
selection in favor of feedback mechanisms that produce the standard phenotype maintains variation:
Term
normalizing
Definition
_____ selection reduces genetic variation
Term
canalizing
Definition
_____ selection maintains genetic variation
Term
canalizing
Definition
(canalizing/normalizing) selection produces a narrower phenotype and is attained through modifier genes
Term
stabilizing
Definition
Ultimate cause of ______ selection often due to opposing agents of selection.
Term
normalizing; directional; stabilizing
Definition
English sparrows are an example of _____ selection.

Larger males survived better (______) selection), but average-sized females survived better (________ selection).
Term
normalizing (stabilizing)
Definition
Human birthweights are an example of ______ selection
Term
relaxed
Definition
In human birthweight, the tails of the parobola are elongating due to _____ selection against the extremes
Term
Stabilizing selection due to opposing agents
Definition
birds and wasps eating different size galls is an example of _______
Term
modifier
Definition
Cryptic genetic variation showed up when
Hsp90 gene is knocked out. Hsp90 (a ______
gene) canalizes polygenic characters
Term
reduce
Definition
Directional & stabilizing selection ______
genetic variation (VA) & heritability (h2)…
Term
disruptive
Definition
Selection that maintains p y p polymorphisms typically involves ______ selection
Term
heterozygote advantage
Definition
A stable equilibrium at which the allele frequencies depend on the balance between fitness values of the 2 homozygotes is known as the _____
Term
heterozygote advantage
Definition
Sickle cell anemia is an example of the _______
Term
malaria vs. anemia
Definition
Opposing selective factors in sickle cell anemia
Term
disruptive
Definition
Selection that favors more than one genotype simultaneously simultaneously (or nearly so), and the intermediate forms are
discriminated against.
Term
disruptive
Definition
_____ selection is a combination of two phases:
1. establishment of a second co-optimal genotype, with
directional selection favoring it, and…
2. persistence of two “adaptive peaks” maintained by
stabilizing selection.
Term
disruptive
Definition
sexual dimorphism, e.g., testosterone levels need to be low
or high; intermediate levels are disastrous (w = 0) is a popular example of _____ selection
Term
genetic polymorphisms. (garter snakes too, but unknown cause)
Definition
Human ______ are developed due to past geographic isolation and reduced gene flow
Term
multiple niche polymorphisms
Definition
Frequency-dependent selection and environmental heterogeneity are the key ingredients that prevent the loss of alleles and create _____
Term
Negative frequency-dependent
Definition
_______ selection is necessary for stable multiple niche polymorphism
Term
negative frequency-dependent selection
Definition
Once the genotype increases in numbers past the ability of the niche to support it, it experiences negative selection pressure.
Term
coarse-grained
Definition
M.N.P. favored by ______
environmental variability – i.e., the individual experiences only one one environmental state in its lifetime
Term
Spatial
Definition
_____ variation favors M.N.P. more than temporal: the latter is best dealt with by phenotypic plasticity & switch mechanisms.
Term
everything must be maintained, spaced out, and independent
Definition
Criteria for stable multiple niche polymorphisms: general idea
Term
local
Definition
In Cepaea nemoralis (shells), darker shells are favored at colder sites, and this is a _____ adaptation
Term
adaptation
Definition
the outcome of natural selection
Term
adaptation
Definition
An ______ is a derived character that evolved in response to a specific selective agent
Term
Exaptation
Definition
An initial adaptation that has been co-opted to serve a new
function.
Term
comparative
Definition
A search for associations between traits and ecological variables, as ways of testing hypotheses of adaptation is known as a ______ method for recognizing adaptation
Term
comparative
Definition
We use ______ methods because it’s impossible (usually) to experimentally re-create the conditions of the past.
Term
Dollo's
Definition
Complex adaptations, once lost, cannot be regained in the same form is known as _____ Law (e.g. insect wing)
Term
modification
Definition
Because of phylogenetic constraints, the evolution of novelty largely involves _____ of existing structures.
Term
dinosaurs
Definition
Birds evolved from ______ via innovation
Term
key innovations and adaptive radiation
Definition
Feathers in archosaurus, mammary glands in mammals, and complete metamorphosis in insects are all examples of _____
Term
evolve
Definition
There must be many ways to achieve high individual fitness. Life history traits ______ under selection, to achieve the highest fitness possible under the conflicting circumstances of existence.
Term
bristle cone; rotifers
Definition
Life history:
Great size and/or great age
(_____), vs. brief lifespans
(______).
Term
size, reproduction, aging, and sex ratio
Definition
4 components focusing around life history evolution
Term
Life history
Definition
_____ traits are those that affect the growth rates of populations.
Term
reproductive success
Definition
Life history traits: R=LM

R = ______ = number of descendants
of an averag g ge female after one generation.
Term
probability of a female’s survival to reproductive
age.
Definition
Life history traits: R=LM

L = _____
Term
fecundity
Definition
Life history traits: R=LM

M = average number of offspring per survivor
(____).
Term
heritable
Definition
life history traits are ____
Term
probability of survival ; fecundity
Definition
Just like R, r depends on the _____
and ____ at each age.
Term
allocation of resources
Definition
Trade-offs are inherent when you must divide up finite
resources – a process known as the ______
among…
• maintenance
• current reproduction
• growth and storage (future reproduction)
Term
trade-offs
Definition
life history traits are connected by _____
Term
otimality; frequency dependence
Definition
_____ = a world at equilibrium.
________ = a changing world; your best
strategy depends on what others do.
Term
Demographics
Definition
Population structure – the details of
reproduction of its constituent members and how those
contribute to population growth.
Term
Demography
Definition
1. At what age should I start to
reproduce?
2. At what size should I start to
a “mast” year for red oaks
reproduce?
3. How many offspring should I
produce at a time?
4. How often should I reproduce
during my lifetime?
5. How long should I live?

Are all questions that can be answered by understanding ______
Term
high
Definition
Delayed onset of reproduction is most likely to evolve in
species with _____ rates of adult survival
Term
lower
Definition
The ____ the annual mortality rate of adults, the later reproduction is selected to begin
Term
inversely
Definition
Age at first reproduction is also _____ correlated with mortality rate
Term
Individual fecundity
Definition
_____ in a hypothetical population as a
function of life span and age at first reproduction
Term
it takes time to grow large
Definition
Small organisms are not small because it improves fecundity
or lowers mortality. They are small because ____ and with heavy mortality, the investment in growth will not be paid back in increased fecundity
Term
sea lions
Definition
_____ are large because of their harem-mating style, and being small would probably get it killed
Term
True
Definition
A parabola peaking starting at 15 and peaking at 30 does NOT mean that the optimal age of
reproduction is 30. Rather, it is somewhere
between 15 & 30 – a compromise between
early reproduction and the experience of age.
Term
marine iguanas
Definition
in ______, if too little food is selecting against larger males, then smaller will become optimal
Term
oysters and other bivalves
Definition
_______ : millions of
eggs/zygotes; only a few will find a favorable place to settle.
Term
Few, but large
Definition
_____ offspring are favored by selection under more
stable, predictable environmental conditions
Term
tsetse flies of Africa (Glossina spp.)
Definition
insects can exhibit this strategy of few but large offspring with parental care, an example being
the ____, which are livebearers of one offspring at a time.
Term
smaller
Definition
Colonizing species, in old-field habitats, tend to produce
____ seeds than species that grow in more stable prairies.
Term
larger
Definition
In the stable habitats (( ) prairie),
competition is more intense,
favoring ____ offspring.
Term
increasing
Definition
the probability that any offspring will survive decreases with
_____ clutch size
Term
an additional trade-off, between a mother’s clutch size in the
first year and her clutch size in future years.

In addition, females reared in nests with smaller clutches had higher
reproductive success (
Definition
Lacks hypothesis of average clutch size being best (8.53) was proved wrong with 12 being the best size, because _____
Term
semelparity
Definition
when an offspring reproduces only once in its lifetime
Term
iteroparity
Definition
when an offspring produces more than once in its lifetime
Term
iteroparous
Definition
the organism will be selected to invest less in the first bout in anticipation of future reproduction – the ____ strategy.
Term
(i) harshness of the environment,
(ii) mating opportunity, and (iii) life span.
Definition
the number of cycles of reproduction
is based on simultaneous interactions
(including trade-offs) among such factors
as
Term
iteroparous
Definition
As _____ individuals age,
the intrinsic disadvantages of
reproducing late in life cut in.
Term
"Big Bang" Semelparous reproduction
Definition
This is a special form of semelparity, in which a single lifetime episode of reproduction characterizes a species with a long lifespan
Term
atlantic salmon
Definition
______ are an example of the "big bang" semelparous reproduction strategy
Term
Tremendous effort entailed in the swim upstream. It is to the
individual’s advantage to do this just once.
Definition
Atlantic salmon's reasoning for "big bang" reproduction strategy
Term
"big bang" semelparous reproduction. endocrine glands genetically program it for death
Definition
Female octopus lay up to 200,000 eggs, defending them and wafting oxygenated water over them. When the eggs hatch,
mother dies. This is an example of:
Term
Annuals
Definition
These are the most commonplant examples of "big bang" semelparity.
Here, it seems to be the interaction of inherently short life span with harsh winter conditions.
Term
harsh conditions, opportunities for germination are rare: their shallow root systems favor delaying reproduction until conditions are just right. YUCCAS: very similar, but deep roots
Definition
Agaves (Century plants) – Grow to “100” years, produce a huge reproductive spire, and die. Why?
Term
physiological decline; Senescense
Definition
Most (sexually reproducing) organisms do not exhibit the
“programmed death, but they DO experience a gradual increase in mortality and decline in fecundity with age: a kind of “______.”
Term
Senescence
Definition
_____ cannot be eliminated by natural selection, because the strength of selection declines on deleterious genes expressed at progressively greater age
Term
sexual maturity
Definition
Senescence begins at _____. It evolves under natural selection just like any other trait.
Term
frequency dependence
Definition
There is negative and positive ______ of
alleles controlling specific life-history traits.
Term
lower
Definition
Life history traits have ____ heritabilities than other kinds of traits
Term
Phenotypic plasticity
Definition
______ can resolve a life-history conflict:
The larva of the geometrid moth Nemoria arizonaria
Term
constraint
Definition
evolutionary history (phylogeny) can be a major
____ on life history evolution, preventing the organism from trying out certain solutions to life history conflicts.
Term
the young can feed themselves
Definition
ducks have large clutch sized because:
Term
long-term evolution of the clade of petrels
under conditions of sparse and unpredictable food supply
Definition
the single egg of petrels could be explained by:
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