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eating disorder/renal
eating disorder lecture
89
Nursing
Undergraduate 4
03/04/2016

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Term
eating disorders
Definition

 

) involve serious disturbances in eating behavior

 

Extreme and unhealthy reduction of food intake

 

Severe overeating

Feelings of distress or extreme concern about body shape or weight

Term
eating disorder statistics
Definition

 

Eating disorders currently affect approximately 25 million Americans

 

Approximately 25% are male

Anorexia has the highest mortality rate among all psychological disorders

Term
contributing factors to eating disorders include
Definition

 Biological factors- genetic model-  risk of developing an eating disorder is 50-80% determined by genetics

Individuals with EDs have a characteristic phenotype:
Constellation of personality traits that have been shown to be moderately heritable
Female relatives of people with EDs are up to 12 times more likely to develop them as well.
Social factors- unrealistic pressures to obtain the "perfect" body; the constant influx of images of perfection; and narrow definitions of beauty
Psychological factors- substantial co-morbidity with other mental health disorders - ie. depression, anxiety
Obsessive-Compulsive Disorder
Low self-esteem
Feelings of lack of control
Interpersonal factors- history of abuse; being teased for size or weight; traumatic life event(s); and difficulty expressing feelings and emotions

 

Term
est lifetime prevalence of developing an
Definition

 

Women, 1%

 

Men, 0.3%

 

Term
est prevalence rate for developing bulima
Definition

 

Women, 1.5%

 

Men, 0.5%

 

Term
prevalance and comorbiditiy of ED
Definition

 

Anorexia nervosa appears in early to middle adolescence.

 

Bulimia nervosa appears in late adolescence.

 

Women (aged 35 to 65 years): Changes in appearance and role potentially increase the risk for EDs.

 

EDs are almost always co-morbid with other psychiatric illnesses.

 

More than 50% of people with anorexia and 95% of those with bulimia have one other psychiatric disorder.

 

Term
comorbidities with ED
Definition

 

Significant co-morbidity with:

 

Mood and anxiety disorders

 

Substance abuse

 

Body dysmorphic disorders

 

Impulse control disorders

 

Personality disorders, especially borderline and obsessive-compulsive personality disorders

 

Always assess for psychiatric risk, including suicidal and self-harm thoughts, plans, and/or intent.

 

Term
hunger influenced by
Definition
leptin
Term
full feeling influenced by
Definition
peptide
Term
dieting influenced by
Definition
cholescystokinin
Term
weight loss influenced by
Definition
insulin
Term
weight loss influenced by
Definition
insulin
Term
weight influence influenced by
Definition

amylin

ghrelin

gastric inhibitory polypeptide

pancreatic polypeptide

Term
range of eating disorders
Definition

 

qMaladaptive eating regulation responses

 

q Inability to regulate eating habits

 

q Frequent tendency to over or under use food

 

q Interference with the biological, psychological

 

     and sociocultural aspects of the person’s life

 

Term
factors that interact in eating disorders
Definition
appetitie, binge eating, body weight, duration rate of eating, food intake, hunger, neurochemicals, intermeal intervals, macronutrient selcetion, meal freq, meal initiation, meal size, saitey, rate of energy expenditure
Term
eating disorder is classified as an...
Definition

addiction

 

Complex neuro-biobehavioral disorder characterized by:

 

impaired control

 

compulsive use

 

Dependency

 

craving for the activity, substance or food

 

 Relapses are possible even after long periods of abstinence

 

“chronic brain disease”

 

Term
craving
Definition

 

Conscious awareness of desire to take a drug or participate in an activity 

 

Complex neuro-biobehavioral phenomenon based on previous experiences with addictive substances or activities

 

Term
obesity
Definition

 

Chronic, relapsing neurochemical disease characterized by individuals having a body mass index (BMI) … 30kg/m(squared) or higher

 

Currently, there is no generally accepted definition of obesity for children and adolescents

 

Term
relapse
Definition

 

Recurrence of problem substance use or activity in someone who was abstinent from that substance use or activity 

 

Considered normal part of cycle of change in the recovery from addiction

 

Involves experiencing a “slip” and reverting to exhibiting  addictive behavior

 

Term
weight cycling
Definition

 

Repeated intentional weight losses followed by regains

 

Also called yo-yo dieting

 

Term
anoerxia nervosa
Definition

 

vPreoccupied with food and rituals of eating, along with voluntary refusal to eat

 

vExhibit morbid fear of obesity and refusal to maintain a minimally normal body weight (<85% expected normal weight)

Occurs most often females from teens to adulthood

Term
two types of AN
Definition

 

vRestricting- drastically restricts food intake and does not binge or purge

 

vBinge-eating/purging

 

Term
AN assessment findings (1)
Definition

 

Orthostatic changes

 

Bradycardia

 

Cardiac murmur

 

Sudden cardiac arrest

 

Prolonged QT interval

 

Acrocyanosis

 

Symptomatic hypotension

 

Leukopenia

 

Lymphocytosis

 

Carotenemia

 

Term
AN assessment findings 2`
Definition

 

Hypokalemic alkalosis

 

Electrolyte imbalances

 

Osteoporosis

 

Fatty degeneration of liver

 

Elevated cholesterol levels

 

Amenorrhea

 

Abnormal thyroid functioning

 

Hematuria

 

Proteinuria

 

Term
nursing diagnoses for AN
Definition

 

Imbalanced nutrition: less than body requirements

 

Decreased cardiac output

 

Risk for injury (electrolyte imbalance)

 

Risk for imbalanced fluid volume

 

Disturbed body image

 

Anxiety and chronic low self-esteem

 

Deficient knowledge

 

Ineffective coping

 

Powerlessness and hopelessness

 

Term
BN and 2 types
Definition

 

ØRecurrently eat large quantities of food over short period of time (binge), may be followed by purging

 

ØWeight normal or slightly higher

 

ØAverage age at onset 15-18 yo

 

ØMost common females

 

Two types:

 

ØPurging- self-induced vomiting, laxatives, diuretics, and or enemas

 

ØNonpurging- excessive exercise

 

Term
BN clinical picture (1)
Definition

 

Cardiomyopathy (ipecac toxicity)

 

Cardiac dysrhythmias

 

Sinus bradycardia

 

Sudden cardiac arrest

 

Orthostatic changes
in pulse and blood pressure

 

Electrolyte imbalances

 

Metabolic acidosis

 

Hypochloremia

 

Hypokalemia

 

Term
BN clinical picture (2)
Definition

 

Dehydration and renal loss of potassium as a result of self-induced vomiting

 

Attrition and erosion of teeth

 

Loss of dental arch

 

Diminished chewing ability

 

Parotid gland enlargement

 

Esophageal tears as a result of self-induced vomiting

 

Gastric dilation

 

Russell sign

 

Term
nursing diagnosis BN
Definition

 

Decreased cardiac output

 

Disturbed body image

 

Powerlessness

 

Chronic low self-esteem

 

Anxiety

 

Ineffective coping (e.g., substance abuse, impulsive responses to problems)

 

Term
binge eating
Definition

 

vClients recurrently eat large quantities of food over short period of time without compensatory behaviors

 

vBoth sexes, ages 46-55

 

vWeight gain associated with increased risk for diabetes, hypertension and cancer

 

vComorbidities- depression, personality disorders, substance use disorders and anxiety

 

Term
cues of self induced vomiting
Definition

 

ÂRussell’s sign – calloused and/or reddened area of  

 

      knuckles on dominant hand

 

ÂSwollen cheeks, throat and parotid glands

 

Â

 

ÂWatery, bloodshot eyes

 

ÂChipped teeth with exposed dentin and/or minimal enamel

 

      coating.

 

Term
purge index
Definition

 

How many times in your lifetime have you engaged in these activities

 

  to lose or maintain your weight?”

 

u   used diuretic pills

 

u

 

v   used laxatives

 

v

 

w   induced vomiting

 

 

 

Term
restriction index
Definition

 

How many times during your lifetime have you engaged in these activities to lose or maintain your weight?”

 

_    Exercised more

 

_

 

_    Fasted

 

_

 

_    Skipped meals

 

_

 

_    Restricted the intake of food

 

Term
binge index
Definition

 

How many times they have engaged in binge eating (rapid and uncontrollable consumption of a large quantity of food) during past month

 

Assess specifics of pattern of binge eating

 

Assess number of times individual has stolen food and/or other items to obtain money to purchase food

 

Term
assessment of ED patients
Definition

 

ùWaist circumference measurement

 

ù Waist-to-Hip ratio

 

ù Skinfold measurements (abdominal, suprailiac, thigh, triceps)

 

ù Computerized Tomography (fat content of body)

 

ùMagnetic Resonance Imaging

 

ùDual energy X-ray absorptiometry

 

ùBioelectric Impedance analysis

 

ùDensitometry

 

Term
female athlete triad
Definition

amenhorea

disordered eating and osteoporosis

Term
overtraining syndrome
Definition
depression, exhaustion, irritability, continue to train but level of performance dec
Term
eating disorder nursing care
Definition

 

vEncourage client decision making and participation in plan of care

 

vMonitor vital signs, intake and output, weight

 

vIncorporate family as able

 

vMental health counseling

 

vNutrition counseling

 

vAnorexia- one-to-one supervision of meals

 

vRefeeding syndrome- potentially fatal complication when fluids, electrolytes and carbs introduced to severely malnourished client-cardiac dysrhythmias, severe bradycardia, hypotension. Monitor electrolytes, cardiac monitoring, fluid replacement

 

Term
reality of treating someone with obesity
Definition

 

Biases

 

2Prejudices

 

2 Stigma

 

2High Potential for Relapse

 

2 Long Term Nature of Diagnosis

 

2 Lack of Funding for Long-Term Care

 

2 Lack of Evidence-Based Treatment

 

2Lack of Success of Most Approaches

 

Term
more realities of treating someone with obesity
Definition

 

~NO TREATMENT for persons who are overweight 

 

    has been given an A or B rating

 

~ 95% of individuals who lose weight regain the weight within 5 years (unfortunately, this statistic also applies to individuals who have had bariatric – weight loss surgery)

 

Term
goal of weight management
Definition

 

vTo empower clients to live healthier, more fulfilled lives by honoring and caring for the bodies they presently have

 

 

v       Focus should be on health promotion and disease prevention rather than physical appearance.

 

 

 

v      Preventing weight gain is critical to preventing overweight and obesity

 

Term
treatment of indiv who are overweight or obese
Definition

 

qPromote weight maintenance as primary initial focus rather thanweight reduction (especially as soon as the person has gained 10 pounds)

 

q Promote health rather than focusing on improving physical appearance

 

qUtilize stages of change framework to promote minimal, realistic changes
vAppreciate the reality of the person having a “chronic neurochemical disease”
v Acknowledge the tendency to avoid health care professionals.
v Professional might initially focus on promoting the change of exercising for 10 minutes 3 days a week rather than a goal of losing a certain number of pounds.

 

Term
holistic approach
Definition

 

-Self-Acceptance

 

- Physical Activity

 

- Normalized Eating

 

- Satisfy Hunger

 

- Stop When Full

 

- Promote perspective that long-term use of diets that omit whole food groups is NOT effective

 

Term
the kidneys
Definition

 

Waste elimination

 

Kidneys filter through 200 quarts of blood to produce 2 quarts of waste each day

 

Regulate electrolytes, acid-base balance, red blood cell production

 

Control BP, fluid balance

 

Secrete prostaglandins-line stomach, released during inflammatory process

 

Calcium/Phosphate balance and Vit D

 

Term
nephrons
Definition

 

Make urine, filtering

 

Urine can be adequately made with >20% of nephrons functioning

 

Do the work

 

Someone in renal failure may still produce urine

 

Ersf-creatinesky high, K sky high

 

Term
loop of henle
Definition
site of reabsorb of K-why Lasix causes hypokalemia
Term
glomerulus
Definition

 

inside nephron)

 

The capillary bed where filtration occurs in the kidney. 

 

Kidneys receive ~25% of total cardiac output-these kidneys rely heavily on blood.

 

Term
bowmans capsule
Definition

 

-where filtration starts

 

Remants work down loop of henle-proximal to distal

 

Term
distal tubule
Definition

 

-renin regulation (severe hypertension-180 systolic)

 

Term
bowman's capsule
Definition

 

(inside glomerulus)

 

Filtered fluid forms at Bowman’s, then travels to the:

 

Proximal Tubule à Loop of Henle

 

Part that adjusts filtrate based on body’s needs, site of re-absorption

 

Distal Tubule

 

Part that regulates renin

 

Term
chornic kidney disease (CKD)
Definition

 

Progressive destruction of kidney nephrons

 

Diagnosed in stages based on GFR after a 3 month sustained decrease.

 

Stage I – GFR ‘normal’ with kidney damage

 

Stage II – GRF = 60-89 ml/min/1.73m2

 

Stage V – GFR < 15 ml/min/1.73m2 (Now End-stage)

 

Gfr naturally dips with age (  ~65)

 

Term
3 major causes CKD
Definition

 

HTN

 

Diabetes mellitus

 

Cardiovascular disease

 

Term
other risk factors for kidney disease
Definition

 

Age >60 years

 

GFR declines naturally with age

 

Acute kidney injury-obstruction, infec (pyelonephritis), unresolved UTI

 

Urinary tract obstruction (e.g., benign prostatic hyperplasia)

 

Autoimmune disease/vasculitis/connective tissue disorder

 

Nephrotoxic drugs (lithium, salicylate, high doses NSAIDs)

 

Congenital anomalies; obstructive uropathy; renal aplasia/hypoplasia/dysplasia

 

Hyperlipidemia

 

Obesity/smoking

 

Term
CKD etiology
Definition

 

Pre-renal (Vascular)-before the kidney

 

Post-renal

 

Obstruction (benign prostatic hyperplasia)

 

Interstitial-tubular

 

Infections usually

 

Glomerular

 

Nephritis

 

Autoimmune (SLE)

 

Term
acute nephritic syndrome
Definition

 

Glomerular inflammation

 

Post-infection (group A beta-hemolytic)

 

Can be acute pylenephritis

 

Viral syndromes

 

Epstein-Barr-common

 

HIV

 

Hepatitis

 

 

Term
presentation of acute nephritic syndrom
Definition

 

Hematuria (common)

 

Edema

 

HTN

 

Fever

 

Headache

 

Flank pain

 

Azotemia

 

Term used to describe elevated BUN and proteinuria. 

 

 

Term
nephricitc syndrome despcription
Definition
full of scabs and lesions-permanent scars, kills out nephrons, can’t make urine
Term
nephrotic syndrome
Definition

 

Increased Glomerular permeability

 

Damage to the capillary membrane

 

Common – occurs as a result of any renal condition

 

Massive increase in protein (albumin)

 

Unable to filter properly

 

Edema (soft, pitting)

 

Peri-orbital-like a moon face

 

Dependent

 

Ascites

 

 

Term
nephrotic syndrome description
Definition

 

beer=nephrotic syndrome

 

Pungent smell, protein foams like beer

 

Low albumin-peeing out protein and its not supposed to, should be reabsorbing

 

Term
assessment of ESRD
Definition

 

Edema

 

Na+ retention

 

Metabolic acidosis-dropped Ph

 

Anemia of chronic disease

 

Kidneys unable to make erythropoietin

 

Increased Phosphate (Ca transfers phos-more free circ from dec Ca)

 

Decreased Calcium

 

Look at GFR, then BUN, then creatinine

 

Term
neuro changes ESRD
Definition

 

Weakness/fatigue (lack of Mag)

 

Confusion-Mag

 

Tremors-Na/Mag

Seizure-Na

Term
skin changes ESRD
Definition

 

Puritis-itching w/o rash

 

Purpura-purple spots

 

Grayish color/dusky

 

Term
cardiovascular changes ESRD
Definition

 

HTN

 

Pitting edema

 

Pericardial effusions

 

Term
pulmonary changes ESRD
Definition

 

Crackles-fluid has to go somewhere

 

Thick sputum

 

SOB

 

Tachypnea

 

Term
GI changes ESRD
Definition

 

Ammonia odor to breath

 

Metallic taste

 

Anorexia (no appetite), nausea

 

GI Bleeding-loss of prostaglandins

 

Term
heme changes ESRD
Definition

 

Anemia

 

Term
musculoskeletal changes ESRD
Definition

 

Cramping

 

Bone pain/fractures

 

Term
acute renal failture (ARF)
Definition

 

Sudden, rapid loss of renal functioning due to damage or severe disease to the kidneys, resulting in metabolic acidosis, multi-system failure, and death.

 

Incidence

 

5% of hospital and 30% of ICU admissions have a diagnosis of acute renal failure (ARF).

 

25% of patients develop ARF while in the hospital.

 

Term
pre renal ARF
Definition

 

(~55%) Pathology secondary to decreased renal perfusion leading to a decrease in glomerular filtration rate (GFR).  BLOOD GOING TO KIDNEYS

 

Volume loss

 

Heart Failure

 

Sepsis

 

Term
intra renal arf
Definition

 

(~45%) Pathology secondary to pathology within the kidney; acute tubular necrosis (no exchange of electrolytes) (ATN) is the most common cause

 

Glomerulonephritis

 

NSAIDs, ACE-I (causes kidneys to work harder), IV dye, Antibiotics (-mycins)

 

Term
post renal ARF
Definition

 

(~5%) Pathology secondary to extrinsic or intrinsic obstruction of the urinary collection system.

 

Stones, tumors, BPH

 

 

Term
pre renal, intra renal, and post renal ARF signs
Definition

 

Pre-renal signs: Tachycardia, orthostatic hypotension, dry mucous membranes, decreased skin turgor; look for stigmata of associated comorbidities such as liver and heart failure, as well as sepsis.

 

Intra-renal signs: Pruritic rash, livedo reticularis, subcutaneous nodules, ischemic digits despite good pulses

Post-renal signs: Suprapubic distension, flank pain, and enlarged prostate

Term
4 phases ARF
Definition
initiation, oliguria, diuersis, recovery
Term
initiation phase ARF
Definition

 

The renal ‘injury’ occurs

 

Term
oliguria phase ARF
Definition

 

Urine output < 400 ml/24 hrs.

 

Elevated levels of urea, creatinine, uric acid, cations (K, Mg, Na)

 

GFR starts to decrease

 

Azotemia

 

Fluid retention

 

Metabolic acidosis

 

Hypertension, CHF, pulmonary edema

 

Term
diuresis phase ARF
Definition

 

Nephrons regenerate

 

Gradual increase in urine output

 

GFR increases again

May dehydrate-IV fluid (NS 80/hour)

Term
recovery phase ARF
Definition

`

Azotemia resolving still

 

BUN, creatinine back to normal or low

 

May take up to 12 months to stabilize completely

 

Term
assessment ARF
Definition

 

Specific gravity is low (normal = 1.010-1.025)

 

One of the first changes to be seen

 

Azotemia develops (either pre-renal or intra)

 

BUN starts to increase based on how much protein is circulating

 

GFR starts to decline next

 

Breakdown of protein causes elevation of K+

 

Progressive metabolic acidosis begins and renal buffering system fails (HCO3)

 

Term
Arf treatment
Definition

 

Treatment - Current treatment is focused on primary prevention, treating the underlying cause, and treating associated complications.

 

– Correcting the associated complications!

 

Mortality up to 90% of patients

 

 

Stabilization - ABCs of resuscitation

 

Treat hyperkalemia emergently, especially with ECG changes.

 

If volume depleted, give IV fluids-hypotonic solution (1/2 normal Saline-will pull fluid out of interstitial).

 

Place a Foley catheter-for strict I and O

 

Term
stabilization ARF
Definition

 

Review drug list: nephrotoxic drugs

 

Always record ins and outs and daily weights.

 

Follow low sodium, low protein ‘renal’ diet

 

Watch for complications, including hyperkalemia, pulmonary edema, and worsening acidosis—all potential reasons to start dialysis!

 

 

Term
hyperkalemia
Definition

> 6.0-6.5 mEq/L

 

Muscle weakness

 

Diarrhea

 

Nausea

 

Cardiac arrhythmias

 

Cardiac arrest

 

EKG changes-peaked T waves

 

Term
treatment of hyperkalemia
Definition

 

Restrict potassium intake

 

Kayexalate - orally or rectally via enema

 

Exchanges K+ for Na+ in large intestine-where it works and what it does

 

Concentrated glucose (D50%) with regular insulin IV

 

Moves ECF potassium              ICF space

 

Insulin            increases permeability of cell membrane

 

Calcium gluconate IV to counteract effects of K+ on heart

 

Term
hypocalcemia
Definition

serum CA less than 9

 

Assessment

 

Chvosteks sign (poke face) /Trousseaus sign(BP cuff hand curls)

 

cardiac effects: arrhythmias

 

seizures

 

muscle cramps and weakness

 

Some EKG changes-QT prolongation to Torsades

 

Treatment

 

calcium chloride or gluconate (oral or IV)

 

calcium with activated vitamin D

 

Term
hyperphosphatemia
Definition

greater than 4.5 mg/dL

 

Assessment

 

Seizures

 

Muscle cramps and weakness

 

Hemolytic anemia

 

Platelet dysfunction

 

Treatment

 

Aluminum hydroxide: amphogel, alternaGEL or alucaps, nephrox

 

Renagel – binds with phosphate in intestine

 

Term
complications ARF
Definition

 

Sepsis, infection, seizures, peripheral edema, CHF, pulmonary edema, arrhythmias, pericarditis, bleeding, GI bleed, hypotension, anemia, hyperkalemia, uremia.

 

Death

 

Term
ARF and medications
Definition

 

Loop diuretics (Lasix/Bumex) commonly used, but are they affective?

 

Dopamine?

 

ACE-I, ARBs (Sartans)-probably not effective

 

Digoxin-pos inotropic

 

Beta-Blockers-block beta blockers to slow hr and dec PR, do nothing regarding renal circ in Peripheries,

Loop diruetics-not effective if GFR less than 20, not really gonna kick out K

Dopamine-causes contractility-causes perfusion, (SE is inc HR)

To control BP CCB’s most effective because they don’t work in kidneys-work in heart and peripheries

Gen 1: diltiazem (Cardizem) dec heart rate, in tachycardicpx such as A fib

Gen 2: Norvasc, amlodipine- only cause peripheral dilation, no effect on HR

****drug you give patients with renal disease-clonidine (catapress), alpha adrenergic blocker, works in brain, non kidney dependent

***Nitrates-dilates

**spiralactone

Dialysis best treatment

 

Term
impaired RBC production and ARF
Definition

Decreased erythropoietin secretion
Shorter RBC life

Anemia

 

Bruising

 

Platelet dysfunction

 

Bleeding disorders

 

Monitor CBC

 

Check for occult blood in urine and stool

 

Epogen to stimulate RBC production

 

Term
impaired skin intergrity and ARF
Definition

 

Skin care

 

Oral care

 

Edematous skin - prone to breakdown

 

Term
high risk for infection and ARF
Definition

 

Weakened immune system

 

Avoid nosocomial infections and others with infectious processes

 

Pneumonia is common

 

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