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Dynamics of Disease Transmission
VCOM 2014
29
Microbiology
Graduate
09/22/2010

Additional Microbiology Flashcards

 


 

Cards

Term
What is a host?
Definition

A person or other living organism that can be infected by an infectious agent under natural conditions and sometimes experimental conditions

 

 

Term
What is an agent?
Definition

A factor, such as a microorganism, chemical substance, or form of radiation, whose presence, excessive presence, or relative absence is essential for the occurrence of a disease.

 

- anything that can cause a disease

Term
Environmental Factors
Definition

An extrinsic factor (geology, climate, insects, sanitation, health services, etc.) which affects the agent and the opportunity for exposure

 

- anything not agent but outside factors influencing exposure of infection

Term
Transmission of Infection
Definition
- Any mode or mechanism by which an infectious agent is spread through the environment or to another person
Term
Locus
Definition
The specific site in or on the body where an infection originates
Term
Portal of Entry
Definition
To gain entry to the body, pathogens must either (1) infect cells in one of the body surfaces (skin, respiratory mucosa, alimentary tract), (2) otherwise breach the surgace (by trauma, bite, or injection), or (3) be transmitted congenitally.
Term
Horizontal Transmission
Definition
Transmission of an infection from one person to another of the same generation in the same population
Term
Vertical Transmission
Definition
Transmission of a disease from mother to child either during pregnancy, childbirth, or by breastfeeding
Term
Contact Transmission
Definition

Exposure to a source of an infection, or a person who is exposed

 

- direct touch (host to host or object to host)

Term
Direct Transmission
Definition
The immediate transfer of an agent from a reservoir to a susceptible host by direct contact or droplet spread
Term
Indirect Transmission
Definition

The transmission of an agent carried from a reservoir to a susceptible host by suspending air particles or by animate (vector) or inanimate (vehicle) intermediaries.

 

(Indirect is the same as direct except some intermediate step is involved in the transfer of the pathogen)

ex/ mosquito (vector)

Term
Droplet Transmission
Definition

The direct transmission of an infectious agent from a reservoir to a susceptible host by spray with relatively large, short-randed aerosols produced by sneezing, coughing, or talking

 

less than 1 meter

Term
Droplet Nuclei
Definition
The residue of dried droplets that may remain suspended in the air for long periods, may be blown over great distances, and are easily inhaled into the lungs and exhaled.
Term
Vector Transmission
Definition

An animate intermediary in the indirect transmission of an agent that carries the agent from a reservoir to a susceptible host

(Vector: usually arthropod, intermediate host)

Mechanical: ex/ flies

Biological: ex/ mosquitos

Term
Parenteral
Definition
Refers to a route of administration that involves piercing the skin or mucous membrane
Term
Fecal/Oral Transmission
Definition
Infectious agent that is shed by the infected host in feces and acquired by the susceptible host through ingestion of contaminated foods or other materials
Term
Airborne Transmission
Definition

Occurs when bacteria, viruses or other pathogens travel on dust particles or on small respiratory droplets that may become aerosolized when people sneeze, cough, laugh, or exhale.

They hang in the air much like invisible smoke.

They can travel on air currents over considerable distances.

 

Term
Sexual Transmission
Definition

Oral

Anal

Vaginal

Term
Carrier Host
Definition

A person or animal without apparent disease who harbors a specific infectious agent and is capable of transmitting the agent to others

 

The carrier state may be of short or long duration (transient carrier or chronic carrier)

Term
Iatrogenic
Definition

Refer to adverse effects or complications caused by or resulting from medical treatment or advise.

 

In addition to harmful consequences of actions by physicians, iatrogenesis can also refer to actions by other healthcare professionals, such as psychologist, therapist, pharmacists, nurses, dentist, etc.

Term
Infectivity
Definition
The proportion of persons exposed to a causative agent who become infected by an infectious disease
Term
Zoonoses
Definition
An infectious disease that is transmissible under normal conditions from animals to humans
Term
Endemic Disease
Definition

Refers to the constant presence of a disease or infectious agent within a given geographic area or population group

 

May also refer to the usual prevalence of a given disease within such area or group

Term
Epidemic
Definition
An increase in rate of expected infection or disease in an area over a specific time
Term
Pandemic
Definition
Multiple epidemics over a great geographic area
Term
Why do we study disease transmission?
Definition
Implementing proper infection control measures
Term
Ways to classify disease transmission
Definition

1. Vertical vs Horizontal

 

2. Portal of entry

 

3. Mode of infection

Term
Modes of transmissions
Definition

1. Contact

(Direct, Indirect, Droplet)

2. Vehicle

(Water borne, Airborne, Foodborne)

3. Vector

(Mechanical, Biologicial)

4. Fecal-Oral

5. Iatrogenic

Term
Vehicle Transmisison
Definition

Airborne (more than 1 meter)

 

Foodborne

 

Waterborne

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