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Dupre Asthma Medicinal Chemistry
Anti-inflammatory drugs; Inhaled Glucocorticoids
6
Pharmacology
Professional
02/29/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Beclamethasone Dipropionate
Definition

Brand: Vanceril

Structure features:

-9chloro

-17' ethyl attached to ether

-16' Beta methyl

Term
Budesonide
Definition

Brand: Pulmicort

Structure features:

-16' and 17' make acetal group

Term
Flunisolide
Definition

Brand: Aerobid

Structure features:

-6 fluoro group

-16 and 17 form acetonide(acetone and ketal group)

Term
Fluticasone
Definition

Brand: Flovent, Flonase

Structure features:

-6 and 9 fluoro group

-16 methyl

-C-20 thiofluoromethyl (presence of sulfur)

Term
Mometasone
Definition

Brand: Asmanex

 

Structure features:

-9 chloro

-16 methyl

-17 furan on ester

Term
Triamcinolone Acetonide
Definition

Brand: Azmacort

 

Structure features:

-9 fluoro

-16 and 17 for acetonide (acetone and ketal)

 

*The acetonide remaines intact during metabolism because it is highly resistant to hydrolytic cleavage.

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