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1. maintain a constant environment 2. transport nutrients 3. remove wastes from metabolism 4. chemical messengers 5. fights infection 6. clotting |
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1. formed elements suspended in clear, straw-colored fluid 2. cells are 45% by volume 3. originate within marrow cavity of bones |
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erythrocytes, leukocytes, thrombocytes (platelets) |
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55% by volume; contains proteins 1. albumins (60%)—maintain normal blood volume/blood pressure 2. globulins (36%)—alpha, beta, gamma 3. fibrinogen (4%)—blood clotting |
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RBCs, life span 120 days; mature cells do not have nucleus; normal values 4.5-6 million per cubic millimeter |
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heme = iron-containing pigment, globin = protein 1. oxyhemoglobin transport oxygen; 2. carboxyhemoglobin = carbon dioxide |
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(a-, granul/o = grains or granules, cyt/o, -e) cells without granules. |
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1. neutrophils (60-70%)—phagocytes; polymorphonuclear leukocytes (PMNs), segmented nucleus (segs) poly- morph/o, nucle/o, -ar 2. eosinophils (2-4%) increase in response to allergic reaction; stain “rosy” pink color. 3. Basophils (<1%) Secrete histamine released in allergic reaction. Secrete heparin (anticoagulant) stain dark blue |
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1. Monocytes (3-8%) --kidney-shaped nucleus not segmented. Phagocytic (phag/o) 2. Lymphocytes (20-25%)—spherical-shaped nucleus |
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1. Immune process; some phagocytic (attack bacteria directly), some produce antibodies to destroy bacteria 2. Cell-mediated immunity. 3. More about these with immunity material. |
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Blood-cell development/morphology |
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VISUAL: reticulocyte (Arrow indicates reticulocyte) |
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Describing changes in blood cell numbers |
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1. -emia = blood condition 2. -osis = condition 3. -penia = too little, too few |
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Describing changes in shape and size |
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1. morph/o = shape or form 2. spher/o = spherical 3. megal/o, mega- = large 4. micr/o, micro- = Small 5. is/o = same, equal 6. poikil/o = varried, irregular |
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Blood clotting--hemostasis IN ORDER |
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1. Injury 2. Platelets “disintegrate”, rupture, break up 3. Thromboplastin Converts prothrombin (blood protein) to thrombin (thromb/o, -in) an active enzyme; requires calcium 4. Thrombin converts fibrinogen (another blood protein) to fibrin (fibr/o, -in); also requires calcium and other clotting factors. 5. Insoluble fibrin threads form mesh that captures cells, creates “plug” for hole.
7. |
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