Shared Flashcard Set

Details

Drugs
Blockers and Promoters
27
Physiology
Graduate
09/06/2010

Additional Physiology Flashcards

 


 

Cards

Term
Tetrodotoxin(TTX)
Definition
Blocker of voltage gated Na channel
Term
Saxitoxin(STX)
Definition

Blocker of voltage gated Na channel

Term
u-conotoxin
Definition

Blocker of voltage gated Na channel

Term
cocaine
Definition

Blocker of voltage gated Na channel

Term
procaine
Definition

Blocker of voltage gated Na channel

Term
lidocaine
Definition

Blocker of voltage gated Na channel

Term
tetracaine
Definition

Blocker of voltage gated Na channel

Term
batrachotoxin
Definition
Promoter of Na channel activity
Term
veratridine
Definition

Promoter of Na channel activity

Term
pyrethrins
Definition

Promoter of Na channel activity

Term
brevotoxins
Definition

Promoter of Na channel activity

Term
Tetraethylammonium (TEA)
Definition
blocks delayed outward rectifiers (K channel)
Term
Dendrotoxin
Definition

blocks delayed outward rectifiers (K channel)

Term
4-aminopyridine
Definition

-Used in Multiple Schlerosis

 

-blocks transient outward rectifiers

(K channels)

Term
Apamin
Definition
blocks calcium activated K channels
Term
Charybdotoxin
Definition
blocks calcium activated K channel
Term
Tertiapin
Definition
blocks inward rectifiers (K channels)
Term
w-conotoxin
Definition

calcium channel blocker

 

-inhibits release of ACh

Term

Botulinum Toxin

(botulism)

Definition
inhibits transmitter release by cleaving protein related to vesicle fusion and exocytosis
Term
Tetanus Toxin (lockjaw)
Definition
inhibits transmitter release from inhibitory neuron for inhibiting muscle contraction
Term
carbamylcholine
Definition

activate ACh receptor-prolong opening of ACh channels

-prolonged depolorization

Term
succinylcholine
Definition

activate ACh receptor-prolong opening of ACh channels

-prolonged depolorization

Term
d-tubocurarine
Definition

competitive inhibitor of ACh binding

 

-no depolorization

Term
physostigmine
Definition

reversible inhibitors of AChE

 

-increased amplitude of EPP

Term
Neostigmine
Definition

reversible inhibitor of AChE

 

-increase amplitude of EPP

Term

Organophosphorous compounds

 

-anatoxin a

Definition

-irreversible inhibitors of AChE

 

-nerve gas

 

-death by flaccid paralysis of muscle

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