Shared Flashcard Set

Details

Drugs
NBME Exam on Renal, Cardio, and Respiratory Drugs
167
Medical
Post-Graduate
01/09/2011

Additional Medical Flashcards

 


 

Cards

Term
Milrinone
Definition
PDE-I (III for CHF)
Term
Amrinone
Definition
PDE-I (III for CHF)
Term
Sildenafil
Definition
PDE-I (V for erectile dysfunction, viagra)
Term
Nifedipine
Definition
Ca Blocker (for Hypertension and Prinzmetal)
Term
Nicardipine
Definition
Ca Blocker (for HTN and prinzmetal)
Term
Amlodipine
Definition
Ca Blocker (for HTN and prinzmetal)
Term
Hydralazine
Definition
Arteriolar vasodilater
Term
Minoxidil
Definition
Arterial vasodilator (or rogaine topically); K channel opener
Term
Losartan
Definition
ARB
Term
Valsartan
Definition
ARB
Term
Candesartan
Definition
ARB
Term
Eprosartan
Definition
ARB
Term
Irbesartan
Definition
ARB
Term
Telmisartan
Definition
ARB
Term
Captopril
Definition
ACE-I
Term
Enalapril
Definition
ACE-I
Term
Lisinopril
Definition
ACE-I
Term
Benazepril
Definition
ACE-I
Term
Fosinopril
Definition
ACE-I
Term
Moexipril
Definition
ACE-I
Term
Quinapril
Definition
ACE-I
Term
Ramipril
Definition
ACE-I
Term
Nitroprusside
Definition
Converted to NO; for HTN crisis or CHF; Acts on veins and arteries; Cyanide toxicity (treated with thiosulfate)
Term
Isosorbide Dinitrate
Definition
Nitroglycerin (coronary arteries and venous vasodilation)
Term
Isosorbide Mononitrate
Definition
Nitroglycerin (coronary arteries and venous vasodilation)
Term
Amyl nitrite
Definition
Nitroglycerin (coronary arteries and venous vasodilation)
Term
Digitoxin
Definition
Digoxin
Term
Ouabain
Definition
Digoxin (glycoside)
Term
Adenosine
Definition
Diagnose SVT, Potassium efflux causing AV heart block
Term
Potassium
Definition
Suppresses ectopic pacemakers; Exacerbates digoxin toxicity
Term
Magnesium
Definition
For Torsades de Pointes, treats digoxin toxicity
Term
Propranolol
Definition
Beta Blocker as antiarrhythmics
Term
Metoprolol
Definition
Beta Blocker as antiarrhythmics
Term
Verapamil
Definition
Ca blocker for SVT (like A fib)
Term
Diltiazem
Definition
Ca blocker for SVT (like A fib)
Term
Sotalol
Definition
Class III Antiarrhythmic (blocks K channel); Also Beta blocking activity
Term
Ibutilide
Definition
Class III Antiarrhythmic (blocks K channel)
Term
Dofetilide
Definition
Class III Antiarrhythmic (blocks K channel)
Term
Bretylium
Definition
Class III Antiarrhythmic (blocks K channel)
Term
Amiodarone
Definition
Class I-IV antiarrhythmic activity; Alpha and Beta blocking activity; For A or V tachycardias; Side effects: pulmonary fibrosis, hepatotoxicity, thyroid dysfunction (and others)
Term
Flecainide
Definition
Class IC Antiarrhythmic (Blocks active Na channel, for SVT, use dependent)
Term
Encainide
Definition
Class IC Antiarrhythmic (Blocks active Na channel, for SVT, use dependent)
Term
Propafenone
Definition
Class IC Antiarrhythmic (Blocks active Na channel, for SVT, use dependent)
Term
Lidocaine
Definition
Class IB Antiarrhythmic (Activated and inactivated Na channel, for VF and VT, use dependent)
Term
Tocainide
Definition
Class IB Antiarrhythmic (Activated and inactivated Na channel, for VF and VT, use dependent)
Term
Mexiletine
Definition
Class IB Antiarrhythmic (Activated and inactivated Na channel, for VF and VT, use dependent)
Term
Qunidine
Definition
Class IA Antiarrhythmic (Blocks active Na channel (and somewhat K channel); For AF and VT; Use dependent); Cinchonism
Term
Procainamide
Definition
Class IA Antiarrhythmic (Blocks active Na channel (and somewhat K channel); For AF and VT; Use dependent); Drug-induced lupus
Term
Disopyramide
Definition
Class IA Antiarrhythmic (Blocks active Na channel (and somewhat K channel); For AF and VT; Use dependent); Urinary retention/constipation/double-vision
Term
Treatment for Strep Viridans subacute endocarditis
Definition
Penicillin G
Term
Treatment for Strep Bovis subacute bacterial endocarditis
Definition
Penicillin; Also indicates ulcerative colitis or colorectal cancer
Term
Treatment for Staph epidermidis acute endocarditis
Definition
Vancomycin (Prosthetic valve associated)
Term
Treatment for Staph aureus acute bacterial endocarditis
Definition
Methicillin (Penicillinase resistant penicillin) or vancomycin (IV Drug user associated)
Term
Treatment for Pseudomonas Aeruginosa acute bacterial endocarditis
Definition
Penicillin + aminoglycoside (gentamicin); Associated with IV drug userss
Term
Treatment for Cocksackievirus myocarditis
Definition
Antiinflammatory
Term
Treatment for pneumococcus lobar typical community aquired pneumonia
Definition
Penicillin G; Amoxicillin; Cephalosporin (1st generation)
Term
Treatment for p. aeruginosa nosocomial, respirators, CF, pneumonia
Definition
penicillin (piperacillin or mezlocillin) + aminoglycoside (gentamicin) + Quinolone (ciprofloxacin) or Macrolide (erythromycin)
Term
Treatment for TB
Definition
Isoniazid+rifampin+pyrazinamide (9-12 months)
Term
Treatment for MAC TB in AIDS patients
Definition
clarithromycin (macrolide) + rifabutin (rifampin) + ethambutol
Term
Treatment for influenza
Definition
NA inhibitors (zanamivir, oseltamivir)
Term
Treatment for chlamydophilia pneumoniae atypical pneumonia
Definition
Doxycycline (tetracycline)
Term
Treatment for chlamydia trachomatis newborn atypical pneumonia
Definition
erythromycin (aminoglycoside)
Term
Treatment for mycoplasma pneumoniae atypical pneumonia
Definition
Erythromycin
Term
Treatment for Coxiella Burnetii diseases (atypical pneumonia, myocarditis, granulomatous hepatitis)
Definition
Doxycycline (tetracycline)
Term
Staph Aureus pneumonia (related to nosocomial, CF, IV drug abuse, abcess formation, etc.)
Definition
Trimethoprim + sulfamethoxazole
Term
Treatment for Corynebacterium diphtheriae (tonsilitis, grey pseudomembrane, Toxin -> myocarditis)
Definition
Erythromycin (macrolide)
Term
Treatment for anthrax
Definition
ciprofloxacin (fluoroquinolone)
Term
Treatment for actinomyces israeli in draining sinus tracts
Definition
Ampicillin/penicillin G
Term
Treatment for Nocardia asteroides (microabcesses in lung; disseminates)
Definition
Trimethoprim+sulfamethoxazole
Term
Treatment for whooping cough
Definition
erythromycin (macrolide)
Term
Treatment for hemophilus influenzae (epiglottitis, sinusitis, otitis media)
Definition
Cefotaxime, ceftriaxone (cephalosporins)
Term
Treatment for Moraxella catarrhalis (typical pneumonia, sinusitis, otitis media)
Definition
Penicillin + clavulanate (Overcomes beta-lactamase resistance for penicillin to work)
Term
Treatment for Klebsiella pneumoniae typical pneumonia (elderly/nosocomial/alcoholics)
Definition
Ceftriaxone (cephalosporin)
Term
Treatment for legionella pneumophila (severe, dry cough pneumonia; JG apparatus destruction, type IV RTA tubulointerstitial disease)
Definition
ciprofloxacin (fluoroquinolone) + azithromycin (macrolide)
Term
Treatment for Yersinia pestis (pneumonic type, but known as bubonic plague, rat flea vector, ground squirrels in southwest; large lymph node blisters);
Definition
gentamicin (aminoglycoside) or doxycycline (tetracycline)
Term
Treatment for cryptococcus neoformans
Definition
fluconazole
Term
Treatment for Aspergillus (allergic type, invasive type)
Definition
Allergic: corticosteroids; Invasive: voriconazole
Term
Treatment for Mucor (Hemorrhagic infacts in lung, frontal lobe invasion, Associated with DKA)
Definition
Amphotericin B
Term
Treatment for dimorphic fungi (Coccidoides, histoplasma, blastomyces)
Definition
Itraconazole
Term
Prophylactic treatment for AIDS patients against PCP
Definition
Trimethoprim and sulfamethoxazole
Term
Theophylline
Definition
Inhibit PDE (Treatment of asthma, bronchodilation (SM relaxation).
Term
Zileuton
Definition
5-lipooxygenase inhibitor
Term
Cromolyn
Definition
Inhibit histamine release from mast cells
Term
Zafirlukast
Definition
Reversible leukotriene receptor blocker
Term
Montelukast
Definition
leukotriene receptor blocker (reversible)
Term
Bupropion
Definition
NE and DA reuptake inhibitors; Block nicotine receptors in brain; smoking cessation
Term
Varenicline
Definition
Nicotinic acetylcholine receptor antagonist in brain; smoking cessation
Term
Ipratropium
Definition
Muscarinic receptor antagonist; COPD and asthma
Term
Albuterol
Definition
Beta Agonist; Asthma, hyperkalemia
Term
Pirbuterol
Definition
Beta agonist; asthma and hyperkalemia
Term
Bitolterol
Definition
Beta agonist; asthma and hyperkalemia
Term
Salmeterol
Definition
Long acting beta agonist; prevent asthmatic attacts
Term
terbutaline
Definition
Beta agonist; treats bronchospasm in asthma attack
Term
Tiotropium
Definition
Muscarinic receptor antagonist; Asthma and COPD
Term
Propantheline
Definition
M3 receptor antagonist; Urinary incontinence
Term
Oxybutynin
Definition
M1-3 receptor antagonist; Urinary incontinence
Term
Beclomethasone
Definition
Inhaled glucocorticoid; chronic asthma treatment; minimal side effects
Term
Clopidogrel
Definition
Thienopyridine; Platelet aggregation inhibitor (P2Y receptor antagonist, inhibits ADP pathway); Acute coronary event and w/ stent placement
Term
Ticlopidine
Definition
Thienopyridine; Platelet aggregation inhibitor (P2Y antagonist, inhibits ADP pathway); Acute coronary syndrome and pre-stent
Term
Dipyridamole
Definition
Inhibits PDE in platelets, Decreased TXA2 synthesis shifting balance towards prostacyclin and away from TXA2; Stroke prevention and cardiac stress test
Term
Acetylsalicylic Acid
Definition
Aspirin; Irreversibly binds COX1/2
Term
Hirudin
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Bivalirudin
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Lepirudin
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Desirudin
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Argatroban
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Melagatran
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Dabigatran
Definition
Direct thrombin inhibitor; for patients that cannot take heparin
Term
Dicumarol
Definition
Warfarin; Inhibits vit K dependent thrombogenic factors in liver; Chronic anticoagulation (e.g. AF)
Term
Enoxaparin
Definition
Heparin; Increases antithrombin III action (degrades factor X); For DVTs, pulmonary embolisms, MI
Term
Dalteparin
Definition
Heparin; Increases antithrombin III action (degrades factor X); For DVTs, pulmonary embolisms, MI
Term
Streptokinase
Definition
Converts Plasminogen to plasmin; Fibrinolytic agent
Term
Urokinase
Definition
Converts Plasminogen to plasmin; Fibrinolytic agent
Term
Anistreplase
Definition
Converts Plasminogen to plasmin; Fibrinolytic agent
Term
Alteplase
Definition
Converts Plasminogen to plasmin; Fibrinolytic agent
Term
Reteplase
Definition
Converts Plasminogen to plasmin; Fibrinolytic agent
Term
Abciximab
Definition
GPIIb/IIIa receptor blocker on platelets; Acute coronary syndrome and w/ PCI
Term
Eptifibatide
Definition
GPIIb/IIIa receptor blocker on platelets; Acute coronary syndrome and w/ PCI
Term
Tirofiban
Definition
GPIIb/IIIa receptor blocker on platelets; Acute coronary syndrome and w/ PCI
Term
Methyldopa
Definition
Alpha-2 agonist (in medulla, decreases NE release, vasodilation w/ decreased CO); For hypertension
Term
Isoproterenol
Definition
B-agonist (; For Torsades de Pointes, cardiac arrest, heart block;
Term
Fenoldopam
Definition
D1 receptor agonist (splanchnic and renal vasodilation); For severe HTN
Term
Clonidine
Definition
Alpha-2 agonist; Acts on brain to increase catecholamines, Increase in CO but larger decrease in vasodilation; For HTN
Term
Clonidine
Definition
Alpha-2 agonist (In medulla, decreased NE release, peripheral vasodilation, decreased CO); for HTN
Term
Phenylephrine
Definition
Alpha-1 agonist (systemic vasoconstriction); For shock
Term
Midodrine
Definition
Alpha-1 agonist; For hepatorenal syndrome
Term
High dose Dopamine
Definition
Alpha-1 agonist; peripheral vasoconstriction; For shock
Term
Dobutamine
Definition
Beta-1 agonist; Increases CO; for CHF and cardiogenic shock
Term
Norepinephrine
Definition
Alpha and Beta-1 agonist; For shock
Term
High Dose Epinephrine
Definition
Alpha and Beta agonist; Severe hypotension
Term
Propanolol
Definition
Beta blocker (Decreased CO, Decreased BP, bronchoconstriction); for HTN, CAD
Term
Nadolol
Definition
Beta blocker (Decreased CO, Decreased BP, bronchoconstriction); for HTN, CAD
Term
Pindolol
Definition
Beta blocker (Decreased CO, Decreased BP, bronchoconstriction); for HTN, CAD
Term
Timolol
Definition
Beta blocker (Decreased CO, Decreased BP, bronchoconstriction); for HTN, CAD
Term
Carvedilol
Definition
Beta blocker and alpha-1 blocker; CHF and HTN
Term
Labetalol
Definition
Beta blocker and alpha-1 blocker; CHF and HTN
Term
Orlistat
Definition
Inhibits pancreatic lipase; Decreases fat absorption; Antiobesity
Term
Gemfirozil
Definition
Fibrates; Stimulates Lipoprotein Lipase; Used to decrease cholesterol and triglycerides
Term
Ciprofibrate
Definition
Fibrates; Stimulates Lipoprotein Lipase; Used to decrease cholesterol and triglycerides
Term
Bezafibrate
Definition
Fibrates; Stimulates Lipoprotein Lipase; Used to decrease cholesterol and triglycerides
Term
Fenofibrate
Definition
Fibrates; Stimulates Lipoprotein Lipase; Used to decrease cholesterol and triglycerides
Term
Niacin
Definition
Decreasing adipose lipolysis; Increase HDL and decrease LDL; (flushing)
Term
Cholestyramine
Definition
Bile acid resin
Term
Colestipol
Definition
Bile acid resin
Term
Colesevelam
Definition
Bile acid resin
Term
Atorvastatin
Definition
HMG-CoA reductase inhibitor
Term
Pravastatin
Definition
HMG-CoA reductase inhibitor
Term
Lovastatin
Definition
HMG-CoA reductase inhibitor
Term
Rosuvastatin
Definition
HMG-CoA reductase inhibitor
Term
Simvastatin
Definition
HMG-CoA reductase inhibitor
Term
Fluvastatin
Definition
HMG-CoA reductase inhibitor
Term
Ezetimibe
Definition
Decreases LDL levels by decreasing cholesterol reabsorption in GI tract
Term
Treatment for UTI
Definition
Trimethoprim-sulamethoxalone
Term
Sevelamer
Definition
Phosphate Binding Resin (for CRF)
Term
Treatment for Malignant HTN
Definition
Nitroprusside
Term
Treatment for Pyelonephritis
Definition
Ciprofloxacin (fluoroquinolone)
Term
Allopurinol
Definition
Xanthine Oxidase Inhibitor (gout, tumor lysis syndrome)
Term
Colchicine
Definition
Microtubular depolymerization; (gout)
Term
Probenecid
Definition
Decreases uric acid reabsorption in prox. tub. of kidney (Gout)
Term
Flutamide
Definition
Androgen receptor antagonist (prostate cancer, given with Leuprolide)
Term
Finasteride
Definition
5-alpha reductase inhibitor; (BPH and prostate cancer)
Term
Vasopressin
Definition
V1 agonist (vasoconstriction); V2 agonist (Increase water reabsorption); For central DI, septic/cardiogenic shock
Term
Desmopressin
Definition
V1 agonist (vasoconstriction); V2 agonist (Increase water reabsorption); For central DI, septic/cardiogenic shock
Term
Prazosin
Definition
Alpha-1 antagonist (decrease BP); For HTN
Term
Terazosin
Definition
Alpha-1 antagonist (Decrease bladder neck contraction); For BPH, HTN
Term
Doxazosin
Definition
Alpha-1 antagonist (Decrease bladder neck contraction); For BPH
Term
Tamsulosin
Definition
Alpha-1 antagonist (Decrease bladder neck contraction); For BPH
Supporting users have an ad free experience!