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Drugs to Know Test 2
Drugs to know test 2
87
Pharmacology
Undergraduate 1
02/07/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Epinephrine (Adrenalin)
Definition

Class/Action: Sympathomimetic (nonspecific)

Used to treat: Anaphylaxis, Cardiac Arrest

Contradictions: glaucoma

Adverse Effects: tachycardia

Term
Albuteral (Proventil)
Definition

Class/Action: Beta2 adrenergic agonist (bronchodilator)

Used to treat: asthma

Contraindications: hypertension

Adverse Effects: tachycardia

Term

Clonidine (Catapres)

Methyldopa (Aldomet)

Definition

Class/Action: selective alpha adrenergic

Used to treat: hypertension

Contraindications: none

Adverse Effects: palpitations, tremors, dizziness

Term

Neosynephrine

Pseudeoephedrine (Sudafed)

Definition

c/a: selective adrenergic

treat: sinusitis, cold

con: HTN, DM

a/e: hypertension

 

Term

Atenolol (Tenormin)

Propanolol (Inderal)

Definition

c/a: Beta blocker

treat: angina, HTN

con: asthma, heart block, many drug interactions

a/e: flushing, H/A, hypetension, laryngospams, reflex tachycardia

Term
Adrenergics & Adrenergics blockers
Definition
Term
Cholinergics & Anticholinergics
Definition
Term
Bethanechol (Urecholine)
Definition

c/a: cholinergic/parasympathomimetic

treat: urinary retention

con: bradycardia, asthma, COPD

a/e: orthstatic hypotension, muscle weakness

Term
Atropine sulfate
Definition

c/a: anticholinergic/parasympatholytic

treat: preop salivation, increase heart rate, tremors

con: glaucoma, obstructive GI disorders

a/e: hypotension, tachycardia

Term

Trihexyphenidyl HCI (Artane)

Benztropine mesylate (Cogentin)

Definition

c/a: anticholinergic

treat: Parkinsons, EPS

con: glaucoma, angina, urinary or GI obstruction

a/e: tachycardia, urinary retention

Term
Tolterodine Tartrate (Detrol LA)
Definition

c/a: antimuscarinic, anticholinergic

treat: incontinence

con: glaucoma, urinary retention

a/e: bronchitis, HTN, chest pain

Term
Central Nervous System Stimulants
Definition
Term
Methylphenidate (Ritalin)
Definition

c/a: amphetamine

treat: ADHD

con: seizures

a/e: hyperactivity

Term
Dextroamphetamine (Dexedrine)
Definition

c/a: anorexian

treat: obesity

con: arrhythmias

a/e: insomnia

Term
Caffeine (No Doz)
Definition

c/a: analeptic

treat: apnea, restore alertness

con: arrythmias

a/e: insomnia, tachycardia

Term
Sumatriptan (Imitrex)
Definition

c/a: selective serotonin1, receptor agonist (Triptan)

treat: migraine, cluster headaches

con: CAD, DM, liver or renal impairment

a/e: hypertension, hypotension, heart block, angina, seizures

Term
Central Nervous System Depressants
Definition
Term

Secobarbital (Seconal)

Pentobarbital (Nembutal)

Definition

c/a: barbiturate sedative

treat: preop sedation, insomnia, seizures

con: resp, renal, hepatic disease, alcohol, or other sedatives

a/e: excess sedation, respiratory depression, laryngospasm

Term
Zolpidem (Ambien)
Definition

c/a: sedative-hypnotic, nonbenzo

treat: insomnia

con: renal or hepatic dysfunction, elderly

a/e: tolerance/dependence, excess drowsiness, confusion

 

Term

Diazepam (Valium)

Midazolam (Versed)

Definition

c/a: benzodiazepine sedative

treat: anesthetic induction, seizure

con: other sedatives, can't mix!

a/e: tolerance, falls, amnesia

Term
Lidocaine (Xylocaine)
Definition

c/a: local anesthetic

treat: local anesthesia

con: bradycardia

a/e: cardiac arrest

Term
Pain Management: Nonnarcotic & Narcotic Analgesics
Definition
Term
Acetaminophen (Tylenol)
Definition

c/a: non-opioid analgesic, anti-inflammatory

treat: mild pain, fever

con: liver disease, alcoholism

a/e: hepatotoxicity, hemorrhage, hypeglycemia

 

Term
Celecoxib (Celebrex)
Definition

c/a: COX-2 inhibitor (NSAID)

treat: chronic pain

con: liver disease

a/e: hepatotoxicity

Term
Morphine sulfate
Definition

c/a: opioid (narcotic)

treat: severe pain, CAD

con: ashtma, ICP, shock

a/e: excess sedation, respiratory depression, itching (common)

Term
Hydromorphone (Dilaudid)
Definition

c/a: opioid (narcotic)

treat: severe pain

con: children, pregnancy

a/e: bradycardia, respiratory depression

Term
Naloxone (Narcan)
Definition

c/a: narcotic antagonist

treat: overdose

con: none

a/e: induces severe pain & seizures if given too fast

Term
Anticonvulsants
Definition
Term

Phenytoin (Dilantin)

Fosphenytoin (Cerebyx)

Definition

c/a: anticonvulsant, hydantoin

treat: seizures

con: heart block

a/e: depression, gingivitis

Term
Gabapentin (Neurontin)
Definition

c/a: anticonvulsant

treat: seizures, neuropathic pain

con: GI ulcer

a/e: GI upset

Term

Carbamazepine (Tegretol)

Clonazepam (Klonopin)

Definition

c/a: anticonvulsant

treat: seizures, neuropathic pain

con: none

a/e: muscle flaccidity, depression

Term
Neurologic Disorders:Parkinsonism & Alzheimer's Disease
Definition
Term
Levo-dopa (Sinemet)
Definition

c/a: antiparkinsons-dopaminergic

treat: Parkinson's disease

con: glaucoma, GI obstruction

a/e: psychosis, depression, hypotension, urinary retention

 

Term
Benztropine (Cogentin)
Definition

c/a: antiparkinson-anticholinergic

treat: Parkinson's, EPS

con: glaucoma, GI obstruction

a/e: muscle weakness

Term
Tacrine (Cognex)
Definition

c/a: acetylcholinesterase inhibitor

treat: Alzheimer's, dementia

con: liver and renal disease

a/e: hepatotoxicity

Term
Neuromuscular Disorders: Myasthenia Gravis, Multiple Sclerosis & Muscle Spams
Definition
Term
Pyridostigmine (Mestinon)
Definition

c/a: Cholinesterase inhibitor

treat: Myasthenia gravis

con: asthma, bradycardia, renal disease, cardiac dysrhythmias

a/e: hypotension, bronchospasm, seizure, cardiac dysrhythmias

Term

Carisoprodol (Soma)

Methocarbamol (Robaxin)

Definition

c/a: muscle relaxant

treat: spasticity, multiple sclerosis, cerebral palsy

con: liver or renal disease

a/e: tachycardia, hypotension, asthma

Term
Antipsychotics & Anxiolytics
Definition
Term
Fluphenazine (Prolixin)
Definition

c/a: antipsychotic (neuroleptic)

treat: psychosis, schizophrenia

con: subcortical brain damage, renal or liver damage

a/e: EPS, tachycardia, tardive dyskinesia, convulsions

Term
Haloperidol (Haldol)
Definition

c/a: antipsychotic, neuroleptic, nonphenothiazine type

treat: acute & chronic psychoses, narcotic withdrawal symptoms, Tourette's, dementia

con: glaucoma, hepatic, renal & cardiovascular disease

a/e: EPS, seizures, urinary retention, laryngospasm, dysrhythmias

Term
Risperidone (Risperdol)
Definition

c/a: atypical antipsychotic

treat: psychosis, schizophrenia

con: dysrhythmias or liver damage

a/e: may cause dysrhythmias, EPS, weight gain

Term

Lorazepam (Ativan)

Alprazolam (Xanax)

Definition

c/a: benzodiazepine anxiolytic

treat: anxiety, preop sedation, status epilepticus, alcohol withdrawal

con: glaucoma, dysrhythmias

a/e: drowsiness, dizziness, confusion

Term
Antibacterias:Macrolides, Tetracyclines, Aminoglycosides, Fluoroquinolones
Definition
Term

Azithromycin (Zithromax)

Erythromycin (EES)

Vancomycin

Definition

c/a: macrolide Ab

treat: Pneumonia, gonorrhea (GC), skin, (for those allergic to PCN) *MRSA

con: hypersensitivity

a/e: diarrhea, hepatotoxicity in high doses, narrow therapeutic window, check BUN/creat

Term
Doxycycline (Vibramycin)
Definition

c/a: Tetracycline Ab

treat: systemic infection, H pylori, gonorrhea (GC), syphilis, Chlamydia, uncommon G+/G- infections

con: reanl, hepatic, hypokalemia, hypersensitivity, alcoholism

a/e: N/V, diarrhea, rash, pruritus superinfectiong (candidiasis)

Term
Gentamicin (Garamycin)
Definition

c/a: Aminoglycoside Ab

treat: Serious G- infections (PID, pseudomonas, MRSA)

con: hypersensitivity, renal disease

a/e: N/V, tinnitus, oto/renal toxicity, monitor labs

Term

Levofloxacin (Levaquin)

(also Cipro, Avelox)

Definition

c/a: Fluoroquinolone Ab

treat: Pneumonia, renal bone, joint infections, Gonorrhea, STDs

con: renal disease

a/e: hypoglycemia, N/V, fatigue, Stevens-Johnson syndrome

Term
Antibacterials:Sulfonamides ("sulfa drugs")
Definition
Term
Cotrimoxazole (Bactrim, Septra)
Definition

c/a: Sulfonamide Ab

treat: systemic infections, UTI, pneumonia, rheumatic fever

con: severe renal/hepatic disease or hypersensitivity

a/e: N/V, vertigo, leucopenia, Stevens-Johnson syndrome, renal failure. Interacts with coumadin.

Term
Sulfazalazine (Azulfadine)
Definition

c/a: Sulfonamide Ab

treat: ulcerative colitis, Crohn's, RA

con: renal disease

a/e: N/V, bloody diarrhea

Term
Silver sulfadiazine (Silvadine)
Definition

c/a: Sulfonamide

treat: burns

con: none

a/e: not near eyes

Term
Antitubercular Drugs, Antifungal drugs, Peptides & Metronidazole
Definition
Term

Isoniazid (INH)

Rifampin (Rlfadin)

Definition

c/a: anti-tubercular

treat: Tuberculosis (TB)

con: renal/hepatic disease, diabetic retinopathy

a/e: drowsiness, tremors, blurred vision, neuropathy

Term

Amphotericin B*

Fluconazole (Diflucan)

Nystatin (Mycostatin)

Miconazole (Monistat)

Definition

c/a: antifungal

treat: candidiasis (fungal infections), oral, vaginal, bladder

con: hypersensitivity

a/e: (*) anaphylaxis-test dose

N/V/D, cramps

Term
Bacitracin (Bactrin)
Definition

c/a: peptide antibacterial (ointment)

treat: skin infections

con: allergies

a/e: neurotoxicity, paresthesias, N/V, renal damage, anemia

Term
Metronidazole (Flagyl)
Definition

c/a: antibacterial, antiparasite

treat: GI/GU infections, (amebiasis)

con: sensitivity

a/e: GI discomfort

Term
Anti-inflammatory Drugs
Definition
Term

Aspirin-acetyl salicylic acid (ASA)

Indomethacin (Indocin)

Definition

c/a: antipyretic, analgesic, anti-platelet, inhibits prostaglandin synthesis

treat: fever, pain, inflammation, clotting

con: bleeding, renal/hepatic disorders, 3rd trimester pregnancy

a/e: tinnitus, GI bleed, GI upset (take with water, milk or food) EC-do not crush

Term

Ibuprofen (motrin, advil, etc)

Ketolorac (Toradol)

Definition

c/a: NSAIDS

treat: fever, pain, inflammation

con: renal, hepatic, asthma, ulcer, bleeding disorders

a/e: GI bleed, GI upset, rash, fatigue, dizziness

Term
Celecoxib (Celebrex)
Definition

c/a: NSAID: COX-2 inhibitor (better on stomach)

treat: arthritis, dysmenorrhea

con: renal, hepatic dysfunction, HTN, GI bleeding

a/e: dizziness, sinusitis, GI upset, peripheral edema

Term
Prednisone, Solumedrol, Dexamethasone
Definition

c/a: corticosteroids

treat: RA (refractory)

con: GI, asthma, (moony)

a/e: taper off dose gradually

Term

Gold (Ridaura)

Infliximab (Remicade)

Definition

c/a: disease modifying antirheumatic drugs (DMARDs)

treat: Rheumatoid arthritis (RA), Crohn's

con: renal, hepatic, colitis, SLA, pregnancy

a/e: metallic taste, rash/dermatitis, hematuria infections, chest pain

Term
Cyclophosphamide (Cytoxan)
Definition

c/a: immune suppressive

treat: sever RA

con: immune dysfunction

a/e: GI, Alopecia, bone marrow sup

Term

Colchicine (Novocolchine)

Allopurinol (Zyloprim)

Probenecid (Benemid)

Definition

c/a: anti-gout/anti-inflammatory, Uricosuric

treat: Gout (disease of kings)

con: renal disease, alcoholism

a/e: take with food, increase fluids; GI upset, rash, prutitus, metallic taste, cataract

Term
Antibacterials:Penicillins & Cephalosporins
Definition
Term
Penicillin (PCN)
Definition

c/a: sulfonamide antibacterial

treat: severe infections

con: allergy

a/e: anaphylaxis

 

Term

Amoxicillin (Amoxil)

Dicloxacillin (Dynapen)

Definition

c/a: broad spectrum penicillin

treat: URI, UTI, sinus, STDs, otitis media

con: PCN allergy, renal disorder

a/e: anemia, stomatitis, diarrhea

Term
Cefazolin (Ancef, Kefzol)
Definition

c/a: 1st gen cephalosporins

treat: respiratory, urinary and skin infections

con: hypersensitivity to cephalosporins

a/e: anaphylaxis, GI upset; monitor liver/renal functions

Term
Cefoxitin (Mefoxin)
Definition

c/a: 2nd gen cephalosporin

treat: severe infections

con: hypersensitivity to cephalosporins

a/e: anaphylaxis, GI upset; monitor liver/renal function

Term
Ceftriaxone (Rocephin)
Definition

c/a: 3rd gen cephalosporin

treat: severe infections

con: hypersensitivity to cephalosporins

a/e: anaphylaxis, GI upset; monitor liver/renal function

Term
Cefepime (Maxipime)
Definition

c/a: 4th gen cephalosporin

treat: severe resistant org

con: hypersensitivity to cephalosporins

a/e: anaphylaxis, GI upset; monitor liver/renal function

Term
Antiviral, Antimalarial & Anthelmintic Drugs
Definition
Term

Amantadine (Symmetrel)

Oseltamivir (Tamiflu)

Definition

c/a: antiviral

treat: influenza A

con: hypersensitivity

a/e: fever, 48hr window

Term
Foscarnet (Foscavir)
Definition

c/a: antiviral

treat: CMV, Herpes/AIDS

con: hypersensitivity

a/e: Rash, N/V/D

Term

Acyclovir (Zovirax)

Valcylovir (Valtrex)

Famciclovir (Famvir)

Ganciclovir (Cytovene)

Definition

c/a: purine nucleoside, antiviral

treat: HSV, HPV, CMV

con: renal, hepatic, hypersensitivity

a/e: N/V/D pruritus, nephroneurotoxicity with aminoglycosides

Term

AZT, Retrovir (Zidovudine)

Indiavir (Crixivan)

Definition

c/a: antiviral, HIV (reverse transcriptase inhibitor + protease inhibitor)

treat: HIV, AIDS

con: renal/hepatic

a/e: diarrhea

Term
Chloroquine (Aralen)(quinine)
Definition

c/a: antimalarial

treat: acute malaria

con: renal

a/e: blurred vision, psychosis, anemia

Term

Mebendazole (Vermox)

Piperazine (Antepar)

Definition

c/a: antihelminth

treat: Trichinosis, helminthiasis

con: liver disease

a/e: GI upset, dizziness, weakness, heachache

Term
Urinary Tract Disorders
Definition
Term
Nitrofurantoin (Macrodantin)
Definition

c/a: urinary antiinfective

treat: UTI (E coli)

con: hypersensitivity, renal impairment

a/e: rust-colored urine, anemia

 

Term
Cirpofloxacin (Cipro)
Definition

c/a: broad spectrum antibacterial (quinolone type)

treat: UTI, soft tissue and joint infections

con: seizure disorders

a/e: photosensitivity avoid sunlight

Term
Trimethoprim-sulfamethoxazole (Bactrim, Septra)
Definition

c/a: sulfonamid antibiotic

treat: serious UTI and otitis media

con: hypersensitivity

a/e: bladder spasms

Term
Phenazopyridine (Pyridium)
Definition

c/a: urinary analgesic

treat: pain of UTI

con: take with Ab

a/e: urine will be red-orange

Term

Oxybutynin (Ditropan)

Flavoxate (Urispas)

Definition

c/a: urinary antispasmodic

treat: cystitis, bladder spasm, incontinence

con: glaucoma

a/e: dry mouth, blurred vision

Term
Aztreonam (Azactam)
Definition

c/a: mixed antibiotic

treat: serious UTI, septicemia, pneumonia

con: renal impairment

a/e: monitor for renal dysfunction

Term
Imipenem/cilastatin sodium (Primaxin)
Definition

c/a: combination antibiotic

treat: serious UTI & other major infections (endocarditis)

con: safety not established

a/e: monitor for renal dysfunction

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