Term
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Definition
Low thyroid function "Hashimoto disease" Causes low TH levels and symptoms of slow metabolism Thyroid works harder and grows larger |
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Term
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Definition
Severe form of hypothyroidism in adults s/s include hair loss, firm & waxy skin, lethargy, seizures |
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Term
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Definition
Hypothyroidism in neonates Causes stunted physical growth and mental retardation |
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Term
Common signs and symptoms of hypothyroidism |
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Definition
Thickened skin, decreased cardiac and respiratory rates (main concern), weight gain, loss of appetite, anorexia, muscle weakness, lethargy |
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Term
TH Replacement Drugs and their intended responses |
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Definition
levothyroxine sodium (Synthroid, Levoxyl) liothyronine sodium (Cytomel, Triostat) Intended responses: Normal vital signs, maintain body weight, mental alertness, intact memory, normal bowel movement pattern |
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Term
Effects of TH Replacement Drugs on other medications |
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Definition
-Enhance the action of Coumadin (increased bleeding) -Decrease levels of Lonoxen -Decrease effects of diabetic medication |
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Term
Side effects of TH Replacement Drugs |
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Definition
Tachycardia, hypertension, warm skin, insomnia, increased bowel movements |
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Term
Adverse effects of TH Replacement Drugs |
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Definition
Angina, heart attack, heart failure, seizures |
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Term
Patient teaching related to TH Replacement Drugs |
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Definition
-Dosage is slowly increased over 2 to 3 weeks -Take exactly as prescribed -Take pulse at scheduled times: before taking drug and before bedtime -Do not take with a fiber supplement as it decreases the effects of the drug -If HR increases by 20 beats/min in 1 week contact physician |
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Term
Lifespan Considerations for TH Replacement Drugs |
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Definition
Pediatric: Safe; medication adjusted with growth spurts Pregnancy and breastfeeding: Category A; may need higher doses; avoid breastfeeding Older Adults: More likely to experience adverse cardiac/nervous system effects Follow-up every 3 to 6 months Patients with diabetes may need higher doses of insulin; frequent blood glucose level checks |
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Term
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Definition
Overactive thyroid Caused by: Graves' disease, tumors, excessive thyroid growth, excessive iodine Also called: thyrotoxicosis (d/t affecting all organs) Faster metabolism |
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Term
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Definition
Cause of overactive thyroid Must have 3 components: Goiter, peritibal edema (swelling of lower legs but not pitting edema), exophalamos (bugging of eyes) |
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Common signs and symptoms of hyperthyroidism |
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Definition
-Skin hot and dry -Increased cardiac and respiratory rates -Weight loss/hair loss -Increased appetite (but loses weight) -Muscle weakness -Nervousness -Irritability -Unable to sleep well -Tremors -Altered menstrual flow |
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Term
Treatment of Hyperthyroidism |
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Definition
Treatments destroys part/all of thyroid gland by: -Surgery (thyroidectomy) -radiation (need to stay home for 48 hours due to being radioactive |
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Term
Thyroid-suppressing drugs (for HYPERthyroidism)and their intended responses |
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Definition
Drugs reduce hormone production prior to surgery -methimazole (Tapazole) -propylthiouracil (PTU) Intended response: Normal everything |
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Term
Sides effects of thyroid-suppressing drugs |
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Definition
Rash, nausea, headache, muscle/joint aches |
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Term
Adverse effects of thyroid-suppressing drugs |
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Definition
Bone marrow suppression (which leads to decreases RBCs which leads to anemia and increase risk for infection), hepatotoxicity, enhances activity of Coumadin |
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Term
What to check before and after administering thyroid-suppressing drugs |
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Definition
Check before: Vital signs, liver function tests Check after: Blood counts; assess for jaundice (due to hepatotoxicity) |
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Term
Patient teaching related to thyroid-suppressing hormones |
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Definition
-Medical follow-up -Regular monitoring of blood counts (INR) -Avoid crowds due to decreased immunity -Monitor for jaundice; report if present s/s of jaundice: yellow discoloration of white part of eyes and skin -Avoid food high in iodine |
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Term
Life Span Considerations for thyroid-suppressing drugs |
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Definition
Pediatric: NOT USED UNDER AGE OF 6; use with caution on short-term basis Pregnancy & Breastfeeding: NOT USED Category D; causes miscarriages; avoid during breastfeeding Older adults: Severe adverse effects more likely |
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Term
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Definition
located behind the thyroid gland with one on each side; Parathyroid hormone (PTH) is secreted in response to a reduction in serum calcium levels |
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Term
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Definition
Need calcitriol to increase calcium absorption; vitamin D supplements may be given (assists in the absorption of calcium and bone resorption) |
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Term
Tips for patients with thyroid disorders |
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Definition
-Too high of a dose will result in nervousness, irritability, and insomnia -Keep a log of pulse, weight, and mood status -For patients with hyperthyroidism: avoid foods high in iodine, such as soy, tofu, turnips, seafood, and iodized salt -Immediately report chest pain -Synthroid takes several weeks to months to reach a therapeutic level (lab tests every 6-12 months after therapeutic level) |
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Term
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Definition
transition time from normal periods to no periods for a full year |
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Term
Effects of high level of follicle stimulating hormone (FSH) |
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Definition
-dilated blood vessels -hot flashes/night sweats -decreased mental concentration |
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Term
Effects of low estrogen levels |
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Definition
-Cause unpleasant changes in skin, vaginal tissues -Increased rate of bone loss (osteoporosis) |
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Term
Hormone Replacement Therapy (HRT) and their intended responses |
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Definition
-conjugated estrogens (Premarin) -methroxyPROGESTERone (Premphase, Prempro)
Intended Response: Replace naturally secreted estrogen/progesterone with exogenous hormones during perimenopausal period -Reduce number, severity of hot flushes/night sweats -Reduce vaginal dryness |
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Term
Side effects of Hormone Replacement Therapy (HRT) |
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Definition
breast tenderness, breakthrough bleeding, fluid-retention weight gain, acne |
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Term
Adverse effects of Hormone Replacement Therapy (HRT) |
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Definition
increased blood clotting, hormone-sensitive cancers; liver impairment; gallbladder disease; pancreatitis |
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Term
Patient teaching related to Hormone Replacement Therapy (HRT) |
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Definition
-take exactly as prescribed -annual screenings for breast, cervical, uterine, ovarian cancer -smoking cessation -monitor/report symptoms of jaundice -seek medical attention for: chest pain, difficulty breathing, swelling in one leg (blood clot), symptoms of a stroke |
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