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Drugs for Angina/MI
n/a
6
Medical
Graduate
10/05/2010

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Cards

Term
Organic Nitrates
Definition
MOA: release or metabolize to NO
activate MLC phosphatase, decrease intracellular ca
ie. Nitroglycerin, isosorbide dinitrate, isosorbide mononitrate
Term
B blockers
Definition
MOA: - inotrophy, decrease renin, may cause increase in myocardial o2 demand
-olol
Term
CCB
Definition
MOA: decrease ca+2 influx into arteriolar vascular smooth muscle
-verapamil, diltiazem, -pines
Term
MISC: ranolazine
Definition
moa: inhibits late Na+ current--> decrease Na+ in exchange for Ca+--> decrease inotrophy, and inhibit FA oxidation
Term
Analgesia IV morphine
Definition
-reduces anxiety, blocks sympathetic outflow form CNS, releases histamine
Term
Thrombolytics
Definition
tPA (aleteplase, reteplase, tenecteplase) & streptokinase
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