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Drugs and Society 3
Chapter 3
50
Science
Undergraduate 1
03/31/2010

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Term
Some Stimulants are..
Definition
natural substances produced by plants.
Term
Cocaine
Definition
from the leaves of the coca plant
Term
Nicotine
Definition
From the tobacco plant leaves
Term
Caffeine
Definition
from coffee bush berries (beans), tea and cola nuts.
Term
Cathinone
Definition
from the khat bush
Term
Arecoline
Definition
from betel nuts
Term
Yohimbine
Definition
from the yohimbe tree
Term
some stimulants are not found in plants but...
Definition
are synthesized in legal pharmaceutical labs or in illegal underground labs.
Term
Some stimulants produce stronger effects than others;
Definition
in general, the y increase the neuronal activity in the central and peripheral nervous system
Term
Physical effects of stimulants
Definition
Release of adrenaline(epinephrine) into the blood from adrenal glands

increase release of norepinephrine at autonomic synapses

Increased Heart, Blood Pressure, and Breathing Rate

Sweating, Dry Mouth, Dilated Pupils

Insomnia, and decreased appetite

Jaw clenching and teeth grinding (High Doses)
Term
Effects of Stimulants on the Body
Definition
Some produce much stronger effects than others, but they all increase the neuronal activity in the central and peripheral nervous system
Term
The Physical effects are mediated by..
Definition
the autonmic nervous system which inerviates the smoooth muscles in blood vessels, organs, and glands.
Term
The Stimulants effects resemble the condition of extreme fear of anger called
Definition
The Fight or Flight Response..
Term
Mental/Emotional Effects
Definition
Increased alertness and attention

Elevated mood, confidence, self-esteem, even euphoria

Irritability, restlessness, paranoia and psychoses (from higher doses)
Term
Strong stimulants such as cocaine or the amphetamines can keep a person awake and energized ...
Definition
but, lack of sleep results in restlessness, irritability, and confusion.
Term
During extended stimulant use (binge use,)
Definition
the body's energy reserves are depleted, and the person must stop their drug intake.
Term
a crash is where..
Definition
the person sleeps a lot and arises only briefly to eat calorie rich meals..
Term
After the crash eases..what happens??
Definition
..an inability to feel pleasure (anhedonia), lack of energy (anergia) and intense craving can initiate another binge cycle.
Term
The Coca plant (Erythroxylon coca), grows mainly on the ...
Definition
..slopes of the Andes Mountains in
South America (Peru, Bolivia, Ecuador, and mainly Colombia). The leaves of the coca bush
contain .5% to1.5% by weight of the alkaloid cocaine; and it takes 250 kg of leaves to make 1 kg of
cocaine.
Term
Chewing the Coca Leaf started in the
Definition
Middle Ages, native cultures in South America used cocaine by chewing the leaves of the coca plant. They often add powdered lime to their saliva to increase cocaine absorption by mucous membranes of the mouth...
Term
Cocaine was isolated from the leaf of the coca bush in ..
Definition
1859 and cocaine hydrochloride was added to many patent medicines and elixirs.
Term
Thomas Edison and President William McKinley endorsed the use of ..
Definition
Vin Mariani (a red wine laced with cocaine).
Term
From 1886 to 1903 a bottle of Coca-Cola contained
Definition
5 milligrams of cocaine.
Term
The invention of the hypodermic needle in 1853
Definition
enabled large doses to be injected
Term
. Injecting cocaine intravenously results in an intense rush within
Definition
30 seconds and produces the highest blood-cocaine level.
Term
Snorting Cocaine
Definition
This method gets the cocaine hydrochloride onto the nasal mucosa where it is absorbed by capillaries located within the nasal membranes
Term
In the 1920's cocaine snorting became popular at
Definition
underground nightclubs that sprang up during alcohol prohibition
Term
When cocaine hydrochloride is converted to freebase cocaine, it lowers the vaporization point to 98°C and makes the drug smokable using
Definition
glass pipes and lighters...
Term
Beginning in the late 60’s, freebasing involved the use of solvents such as...
Definition
ether to dissolve the cocaine powder and then precipitate out pure cocaine freebase crystals...
Term
A new method called “cheap basing” or “dirty basing” uses simple household products such as..
Definition
baking soda, water, and heat to precipitate crystals called crack.
Term
is metabolized very quickly by the body, its’ peak effects last for about
Definition
40 minutes, or less, depending on how it is administered.
Term
Medical Use of Cocaine
Definition
..is the only naturally occurring topical anesthetic that also constricts local blood vessels, to numb the nasal passages when inserting breathing tubes and to numb the nose, eye or throat during surgery.
Term
The crash from cocaine can be very debilitating, with the individual sleeping for
Definition
12 hour stretches yet unable to perform normal activities due to feelings of exhaustion and depression
Term
Withdrawal sets in after recovery from the crash and includes the inability to
Definition
experience pleasure (anhedonia), lack of energy or motivation (anergia), and intense craving for the drug.
Term
Polydrug use occurs when users turn to downers like
Definition
alcohol, Valium, or heroin to ease the intense irritation and restlessness causes by binge use
Term
Adulteration of the drug includes additives such as
Definition
....baby laxatives, lactose or procaine.
Term
Overdose is when a..
Definition
a very rapid heartbeat, chest pain, and hyperventilation, often accompanied by a feeling of impending death.
Term
Smoked cocaine is delivered to the brain faster than
Definition
any other method of intake.
Term
Crack is not cheaper per gram than cocaine hydrochloride; it is just sold
Definition
in smaller, more affordable units.
Term
Ten to twenty dollars of crack buys a few rocks
Definition
fill a pipe bowl
Term
Setting up a dirty basing site was easy in
Definition
abandoned houses and poor neighborhoods became saturated with crack houses
Term
Street names of amphetamines include...
Definition
"speed," "crack," "crystal," "ice," "shabu," and "glass"
Term
Amphetamines are powerful artificial stimulants that can be
Definition
injected, eaten, snorted, or smoked
Term
Illegal manufacture of Amphetamines is risky because
Definition
of toxic fumes and explosions
Term
Amphetamines were first discovered in the late 1800's and they were used medically in the 1930's to treat
Definition
asthma, obesity and depression
Term
Street "speed" supplied demand after the Controlled Substance Act of 1970
Definition
restricted sale of legal amphetamines
Term
Street chemists increased production of "crank" and "crystal"
Definition
in the 80's..
Term
"Ice," a smokable form of methamphetamines, began to be used
Definition
in the 1990's
Term
When amohetamines are taken orally,
Definition
they have a bitter taste
Term
Less popular routes of taking amphetamines are
Definition
injection and snorting because of the irritating effects
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