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Drugs Affecting Choinergic Function
na
6
Nursing
Undergraduate 2
02/15/2012

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Term
nicotinic receptors
Definition

activation of nicotinic receptors in adrenal medulla result in release of epinephrine

stimulation of nicotinic receptors result in skeletal muscle contraction

Term
muscarinic receptors
Definition
stimulation of the receptors results in the pharmacologic response of vasodilation, resulting in decreased blood pressure
Term
disorders that respond to cholinergic stimulation
Definition
bronchi, cardiovascular system, GI tract, genitourinary tract, skeletal muscle, eyes, various glands
Term
muscarinic agonists
Definition

bind to muscarinic receptors throughout the body

elicits a response that resembles the action of the PNS

prototype: pilocarpine (Akarpine)

Term
indirect-acting cholinergic agonists
Definition

inhibits cholinesterase, keeping ACh in synaptic gap keeps stimulating nerve

prototype: neostigmine (Prostigmin)

Term
cholinergic antagonists
Definition

drugs that block muscarinic or nicotinic receptors directly

competitive inhibitor of cholinergic receptors

lower BP

prototype: atropine

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