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Drugs 201+
pharmacy practice drugs 201+
32
Pharmacology
Graduate
04/22/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Benztropine Mesylate
Definition

Cogentin

 

Extrapyramidal disorders;

 Parkinsonism Antiparkinson Agent/Anticholinergic agent

 

--serious dehydration --sudden stoppage may cause symptoms to return --not recommended for children under 3

Term
Ropinirole HCL
Definition

Requip

Parkinson's disease; moderate to severe restelss legs syndrome

 

Antiparkinson/non-ergoline dopamine agonist

 

--reported sudden initiation of sleep without warning. possibility of hallucinations

Term
Pramipexole Dihydrochloride
Definition

Mirapex

Idiopathic Parkinson's Disease and Restless Leg Syndrome Antiparkinson Agent

 

--acts primarily on striatum and substantia nigra

Term
Donepezil
Definition

Aricept

 

Dementia of the Alzheimer's type (moderate)

 

Agent for Alzheimer's dementia/reversible acetylcholinesterase inhibitor

 

--take in the evening just before going to bed --may be taken with or without food --name brand only

Term
Memantine Hydrocholoride
Definition

Namenda and Namenda XR

 

moderate to severe dementia of the Alzheimer's type

 

Agent for Alzheimer's dementia/Uncompetititive NMDA (N-mething-D-aspartate) receptor antagonist

Term
Meclizine Hydrochloride
Definition

Antivert

 

control of vertigo due to diseases affecting vestibular system, motion sickness

 

antivertigo agent/histamine (H1) receptor blocker

Term
Etonogestrel & Ethinyl Estradiol
Definition

NuvaRing

 

prevention of pregnancy

 

contraceptive/suppression of LH and FSH

 

keep regfrigerated; caution if smoking; antibiotics can reduce effectiveness

Term
Estrogens (Conjugated)
Definition

Premarin

 

treat symptoms of menopause and female hypogonadism

 

sex hormone/estrogen

 

--barbituates, rifampin, and/or hydantoins may increase metabolism and elimination --estrogens have been reported to increase the risk of endometrial carcinoma and cardiovascular events

Term
Estrogens (Conjugated) & Medroxyprogesterone
Definition

Prempro

 

vasomotor symptoms of menopause; treatment of vulvar and vaginal atrophy;

 

osteoporosis naturally occurring estrogen and progestin

 

--may cause cholestatic jaundice, hirsutism (hair growth) and alopecia (hair loss)

Term
Estradiol (topical)
Definition

Vivelle-Dot

 

menopause-associated vasomotor symptoms;

 

vulva/vaginal atrophy hormone/estrogen

 

--do not take if pregnant; do not administer near waisteline; drug metabolism enhanced by barbiturates/hydantoins

Term
Estradiol
Definition

Estrace

 

--2 forms: tabs and vaginal cream

 

atropic vaginitis and prevent osteoporosis associated with menopause estrogen hormone

Term
Oral Contraceptives (combo) -Levonorgestrel with Ethinyl Estradiol Triphasic (Trivora, Triphasil, Enpresse) -Norgestimate & Ethinyl Estradiol (Tri-cyclen, Tri-cyclen low, TriSprintec, Trinessa) -Drospirenone & Ethinyl Estradiol (Yasmin, Ocella) *know there are mono-, di- and tri- forms)
Definition
Missed Dose: -If 1 tablet missed, take it as soon as possible or take 2 tabs the next day and continue regular cycle -If 2 tablets are missed during 1st 2 weeks of a cycle: take 2 tablets for 2 days then continue normal schedule. -If 3 tablets are missed or 2 tablets in 3rd week of a cycle: start a new cycle that day or the following Sunday. (Trivora and TriCyclen-7 days after last dose) -Suppresses luteinizing hormone(LH) and follicle stimulation hormone(FH). -Oral contraceptives should not be taken with broad spectrum antibiotics and St. John’s Wort.
Term
Alendronate Sodium
Definition

Fosamax

 

-bisphosphonates treatment of osteoporosis in postmenopausal women; increase bone mass in men with osteoporosis osteoporosis agent

 

--do not take if you can't sit or stand for longer than 30 minutes --take in the morning at least 30 minutes before eating/drinking anything --requires counseling

Term
Risedronate Sodium
Definition

Actonel

 

-bisphosphonates

 

Indications: Postmenopausal osteoporosis; glucocorticoid-induced osteoporosis

 

Class/Subclass: Osteoporosis Agent/Bisphosphonate

 

Comments: Must take in an upright position with a full glass of water. Do not lie down for at least 30 minutes after taking

Term
Raloxifene Hydrochloride
Definition

Evista

 

Indications: Osteoporosis and Risk of Invasive Breast Cancer in Postmenopausal Women

 

Class/Subclass: Osteoporosis Agent/Selective Estrogen Receptor Modulator

 

Comments: Black Box Warning: Increased risk of venous thromboembolism and death from stroke

Term
Levothyroxine Sodium
Definition

Synthroid, Levoxyl, Levothyroid

 

Dosage Forms: Tablets, injections Indications: Thyroid Hormone Replacement (hypothyroidism), also used during Myxedema coma or stupor (intravenously)

 

Hormone/ Thyroid Hormone

Term
Thyroid, dessicated
Definition

Armour Thyroid

 

Indications: -hypothyroidism -Pituitary thyroid stimulating hormone (TSH) suppression -various types of euthyroid goiters -thyroid nodules -subacute or chronic lymphocytic -multinodular goiter -thyroid cancer

 

Class/Subclass: Hormone/Thyroid Hormone

 

Comments: --this drug is prepared from the thyroid gland of pigs. --armour thyroid can decrease vitamin K dependent clotting factors this drug treatment is not beneficial for weight loss for obese individuals --estrogens can decrease serum thyroxine levels.

Term
Vitamin D, Ergocalciferol
Definition

Drisdol

 

Indications: Refractory rickets aka Vitamin D resistant rickets; hypoparathyroidism

 

Class/Subclass: Vitamin/Supplement Comments:

 

Remember that parathyroid hormone (PTH) is the primary hormone for calcium homeostasis

Term
Folic Acid
Definition

Folate --OTC and RX

 

Indications: Megaloblastic anemias, anemias during pregnancy and lactation

 

Class/Subclass: Vitamin

 

Comments: Do not discontinue therapy without first consulting physician.

Term
Potassium Chloride
Definition

Klor-Con, K-Dur, Micro-K

 

Indications: potassium deficiency

 

Class/Subclass: Misc. Hormone and Electrolyte Agents/Electrolyte

Term
Tolterodine
Definition

Detrol & Detrol LA

 

Indications: Overactive bladder

 

Class/Subclass: Urinary Bladder Modifier/ Muscarinic receptor antagonist

 

Comments: Side effects are dry mouth or blurred vision.

Term
Oxybutynin Chloride
Definition

Ditropan & Ditropan XL

 

Indications: Relief of symptoms of bladder instability, overactive bladder

 

Class/Subclass: Urinary Bladder Modifier/Antispasmodics

 

Comments: Avoid prolonged exposure to hot weather.

Term
Dutasteride
Definition

Avodart

 

Indications: Treatment of benign prostatic hyperplasia in men with enlarged prostate gland

 

Class/Subclass: Prostate Anti-inflammatory/competitive and selective inhibitor of type 1 and 2 forms of 5-alpha-reductase

 

Comments: --Women who are pregnant should not come into contact with dutasteride capsules --Men shouldn’t donate blood until 6 months after last dose

Term
Tamsulosin Hydrocholoride
Definition

Flomax

 

Indications: Benign prostatic hyperplasia

 

Class/Subclass: Prostate anti-inflammatory/ Selective alpha-adrenergic blocker

 

Comments: Tamsulosin will let it flo to the max. --Take dose one-half hour following the same meal every day --Keep out of sunlight --May cause dizziness when rising from sitting position

Term
Finasteride
Definition

Proscar

 

Indications: Treatment and risk reduction of symptomatic benign prostatic hyperplasia

 

Class/Subclass: Prostate Anti-inflammatory/5-alpha-reductase inhibitor

 

Comments: Drug is also available as Propecia (1mg) which is used for hair loss.

Term
Phenazopyridine HCL
Definition

Pyridium

 

Indications: Symptomatic relief of urinary discomfort

 

Class/Subclass: Urinary Tract Analgesic

 

Comments: May turn urine orange/red

Term
Sildenafil Citrate
Definition

Viagra

 

Indications: Erectile Dysfunction Pulmonary arterial hypertension (Revatio only)

 

Class/Subclass: Agent for Erectile Dysfunction/ Phosphodiesterase Type 5 inhibitor

 

Comments: initially studied for use in hypertension and angina pectoris Contraindications: -Do Not Use with Nitrates -Cardiovascular Risk -Recent Heart Attack or Stroke -Hypotension -Hepatic or Renal impairment Side Effects: -Intraocular Pressure -Priapism

Term
Tadalafil
Definition

Cialis

 

Indications: Treatment of Erectile Dysfunction

 

Class/Subclass: Agent for E.D/ Phosphodiesterase Type 5 Inhibitor

 

Comments: Available as a daily or as needed dose

Term
Methotrexate
Definition

Methotrexate

 

Indications: Gestational Choriocarcinoma, Chorioadenoma Destruens, Breast Cancer

 

Class/Subclass: -Antimetabolite/Dihydrofolic Acid Reductase Inhibitor

 

Comments: Methotrexate prevents growth rate!

Term
Chlorhexidine Gluconate
Definition

Peridex & Periogard

 

Indications: Gingivitis

 

Class/Subclass: Antiplaque Rinse/ Antimicrobial agent

 

Comments: A periodontist works on gums and Periogard® guards your gums

Term
Verencicline Tartrate
Definition

Chantix

 

Indications: Aid in the cessation of smoking

 

Class/Subclass: --Smoking Cessation Aid --Varenicline Tartrate is a partial agonist at nicotinic receptors in the brain

Term
Phentermine HCL
Definition

Adipex-P and Lonamin

 

Indications: Short-term adjunct to diet plan to reduce weight

 

Class/Subclass: Weight Management/CNS Stimulants

 

 

Comments: -May cause insomnia -May cause dizziness -May be habit-forming

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