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Drug Therapy
Definitions (continuation of Dosages and Terminology)
15
Pharmacology
12th Grade
01/06/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

 

 

Absorption

Definition
Process where drug is taken from administration site and transported to blood stream; occurs orally, topically, rectally, parenterally, and inhalation
Term

 

 

Distribution

Definition
Process that delivers drug through blood stream to specific organs and tissues to apply pharmacological effects
Term

 

 

Metabolism

Definition
Disappearance of a drug--changes in to another compound; takes place primarily in liver; usually enhances excretion and inactivation of a drug
Term

 

 

Excretion

Definition
Process by which the drug is eliminated from the body (usually kidney); excreted via urine, feces, lungs, skin, etc.
Term

 

 

Adverse Effects

Definition

 

 

Effects not desired

Term

 

 

Side Effects

Definition
predictable and widely reported; undesired pharmacological effect of a drug seen when dose is followed; often unavoidable (e.g. nausia, drowsiness, upset stomach, addiction)
Term

 

 

Toxicities

Definition

Effects that are harmful and destructive to body; caused by overdose, used for longer periods than recommended, or drug not properly monitored

(e.g. Chemotherapy kills ALL cells)

Term

 

 

Cross Sensitivity

Definition

 

Allergic to drugs chemically similar (e.g. Penicillin and Ceflasporin)

Term

 

 

Drug Interactions

Definition
Tech should notify pharmacist; change in magnitiude or duration of pharmacological response of one drug b/c of presence of another drug
Term

 

 

Possible Detrimental Effects

Definition

 

Increased risk of side effects and toxicities; decreased pharmacological response desired

Term

 

 

Possible Beneficial Effects

Definition

 

 

Additive response; synergistic response

Term

 

 

Additive Response

Definition

 

Occurs when two or more drugs combined together yield a response when the drugs were ineffective seperately

Term

 

 

Synergistic Responses

Definition

Occurs when the effect of two or more drugs is greater than the sum of the two drugs (2+2=4)

(e.g. Bactrim, Septra, Trimenthoprim, and Sulfamethoxazole)

Term

 

 

A Theoretical Ratio

Definition

Weigh risks v. benefits; must be done on an individual basis

(e.g. Asthma pt should not be on a B blocker, initially)

Term

 

 

Contraindicated

Definition

When a drug used for one thing causes a spike in severity of another indication

(e.g. Pseudoephendrine contraindicated in htn)

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