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Drug quiz #6
Coronary/Cardiac
148
Pharmacology
Graduate
03/15/2011

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Cards

Term
Abciximab brand name
Definition
Reopro
Term
Reopro generic name
Definition
Abciximab
Term
Reopro/abciximab indication
Definition
Cardiac ischemia prophylaxis with PCI
Term
Adenosine warnings
Definition
Heartblock, arrhythmia, bronchoconstriction
Term
Reopro/abciximab doseing
Definition
0.25mg/kg IV bolus prior to PCI and 0.125mcg/kg/min for 12h after PCI
Term
Reopro/abciximab contraindications
Definition
Bleeding, oral anticoag w/in 7d, thrombocytopenia, surgery/trauma, intracranial neoplasm, arteriovenous malformation, aneurysm, HTN, vasculitis, IV dextran
Term
Reopro/abciximab warnings
Definition
bleeding
Term
Reopro/abciximab drug interactions
Definition
Heparin, anticoags
Term
Reopro/abciximab side effects
Definition
Bleeding and thrombocytopenia
Term
Adenosine brand name
Definition
Adenosine
Term
Adenosine generic name
Definition
Adenosine
Term
Adenosing indication
Definition
Conversion to sinus rhythm
Term
Adenosine contraindications
Definition
2nd and 3rd deg AV block and sinus node disease
Term
Adenosine dosing
Definition
6mg IV bolus
Term
Adenosine drug interactions
Definition
none listed
Term
Adenosine side effects
Definition
facial flushing, SOB, chest pressure, nausea
Term
Amiodarone brand name
Definition
Cordarone
Term
Cordarone generic name
Definition
Amiodarone
Term
Amiodarone indication
Definition
Ventricular fibrillation, ventricular tachycardia
Term
Amiodarone dosing
Definition
150mg/10min then 360mg slow IVIF/6h then 540mg/18h
Term
Amiodarone contraindications
Definition
Cardiogenic shock, iodine hypersensitivity, bradycardia, 2nd and 3rd degee AV block
Term
Amiodarone warnings
Definition
Brady cardia, AV block, neonatal hypo/hyperthryoidism
Term
Amiodarone drug interactions
Definition
3A4 and 2C8 inhibitors, cimetidine, cyclosporine, simvastatins, dig, bb, warfarin, rifampin, st. johns wort, fentanyl, dextromethorphan, cholestyramine, disopyramide, flouroquinolones, macrolides, azoles
Term
Amiodarone side effects
Definition
Fever, hypotension, bradycardia
Term
Amphadase brand name
Definition
Hyaluronidase
Term
Hyaluronidase generic name
Definition
Amphadase
Term
Hyaluronidase/amphidase indication
Definition
Absoprtion/disperson of injected drugs, hypodermoclycisis, resorption of radiopaque agents
Term
Hyaluronidase/amphadase dosing
Definition
50-300u
Term
What drug might you do a 3u skin test to determine hypersensitivity prior to administration?
Definition
Hyaluronidase/amphadase
Term
Hyaluronidase/amphadase warnings
Definition
do not use w/ dopamine or alpha agonists, don't apply to cornea and don't inject IV
Term
Hyaluronidase/amphadse drug interactions
Definition
No major interactions
Term
Hyaluronidase side effects
Definition
Inj site rxn, edema, allergic rxn
Term
Argatroban brand name
Definition
Argatroban
Term
Argatroban generic name
Definition
Argatroban
Term
Argatroban indication
Definition
anticoagulant
Phrphylaxis/Tx of thrombosis in HIT
Term
Argatroban dosing
Definition
2mcg/kg/min/continuous infusion
Term
Argatroban contraindications
Definition
Major bleed
Term
Argatroban warnings
Definition
Hemorrhage
Term
Argatroban drug interactions
Definition
antiplatelet agents, antricoags, thrombolytics
Term
Argatroban side effects
Definition
bleeding, hypotension, fever, diarrhea, nausea
Term
Dipyridamol/ASA brand name
Definition
Aggrenox
Term
Aggrenox generic name
Definition
Dipyridamole/ASA
Term
Aggrenox indication
Definition
Stroke risk rdxn
Term
Aggrenox dosing
Definition
200/25mg cap BID
Term
Aggrenox contraindications
Definition
NSAID allergy, syndrome of asthma/rhinitis/nasal polyps
Term
Aggrenox warnings
Definition
GI bleed, intracranial hemorhage, hepatic/renal insuf (alcoholism worses aforementioned), fetal harm
Term
Aggrenox drug interactions
Definition
NSAIDs
Term
Aggrenox side effects
Definition
HA, dyspepsia, abd pain, N/D
Term
Bivalrudin brand name
Definition
Angiomax
Term
Angiomax generic name
Definition
Bivalrudin
Term
Angiomax/bivalrudin indication
Definition
DTI for HIT, PCI and UA
Term
Angiomax/bivalrudin dosing
Definition
75mg/kg IV bolus then 1.75mg/kg/hr IVIF
Term
Angiomax/bivalrudin contraindications
Definition
Major bleed
Term
Angiomax/bivalrudin warnings
Definition
Bleeding, coronary artery brachytherapy
Term
Angiomax/bivalrudin drug interactions
Definition
Heparin, warfarin, thrombolytics, GPI
Term
Angiomax/bivalrudin side effects
Definition
Bleeding, HA, thrombocytopenia, fever
Term
Chlorothiazide brand name
Definition
Chlorothiazide
Term
Chlorothiazide generic name
Definition
Chlorothiazide
Term
Chlorothiazide indication
Definition
Edema in CHF, cirrhosis and steroid therapy
Term
Chlorothiazide dosing
Definition
500-1000mg (1gm) qd-bid IV
Term
Chlorothiazide contraindications
Definition
Anuria, Sulfa hypersensitivity
Term
Chlorothiazide warnings
Definition
Children, renal risease, hypatic dysfxn, systemic lupus
Term
Chlorothiazide drug interactions
Definition
Lithium, alcohol, barbiturates, narcotics, antidiabetics, antihypertensives, corticosteroids, acth, pressor amines, skeletal muscle relaxants, NSAID
Term
Chlorothiazide side effects
Definition
weakness hypotension, pancreatitis, jaundice, n/v/d, anemia, anaphylatic rxn, fever, rash, hyperglycemia, glycosuria, vertico, HA, SJS,
Term
Enalaprilat brand name
Definition
Vasotec Inj
Term
Vasotec inj generic name
Definition
Enalaprilat Dihydrate
Term
Vasotec indication
Definition
HTN
Term
Vasotec dosing
Definition
0.625mg IV over 5min
Term
Vasotec warnings
Definition
Angioedema, neutropenia, agranulocytosis, hepatic gailure, fetal harm/mortality
Term
Vasotec drug interactions
Definition
Gold, anihypertesnives, NSAID, lithium
Term
Vasotec side effects
Definition
Hypotension, HA, nausea
Term
Vasotec BLACK BOX WARNING
Definition
Do not use in 2nd or 3rd trimester = injury/death
Term
Eptifibatide brand name
Definition
integrillin
Term
Inregrilin generic name
Definition
Eptifibatide
Term
Eptifibitied indication
Definition
ACS, PCI
Term
Eptifibatide dosing
Definition
180mcg/kg IV bolus then 2mcg/kg/min infusion
Term
Eptifibatide contraindications
Definition
Bleeding/Hx of bleed, severe HTN, surgery, Hx stroke, concurrent GPIIBIIIA inhib, dialysis
Term
Eptifibatide warnings
Definition
Bleeding, renal insufficiency, ptlt count less than 100k
Term
Eptifibatide drug interactions
Definition
None listed
Term
Eptifibatide side effects
Definition
Bleeding, thrombocytopenic, alergic rxn
Term
Romazicon generic name
Definition
Flumazenil
Term
Flumazenil brand name
Definition
romazicon
Term
Romazicon/flumazenil indication
Definition
reversal of benzos
Term
Romazicon/flumazenil dose
Definition
0.2mg/2ml IV
Term
Romazicon/flumazenil contraindicaiton
Definition
Pt using benzo to control lifethreating condition, signs of serious cyclic antidepressant overdose
Term
Romazicon/flumazenil warning
Definition
Seizure, hypoventilation
Term
Romazicon/flumazenil side effects
Definition
seeizure, inj site pain, vomiting, hypoventilation,DZ, agitation
Term
Romazicon/flumazenil blackbox warning
Definition
Seizure esp longterm benzo or cyclic anti-depressant use
Term
Gadopentetate dimeglumine brand name
Definition
Magnevist
Term
Magnevist generic name
Definition
Gadopentetate Dimeglumine
Term
Magnevist indication
Definition
Facilitate visualization in MRI
Term
Magnevist dose
Definition
0.2ml/kg IV
Term
Magnevist contraindication
Definition
Chronic/severe kidney disease, AKI
Term
Magnevist warnings
Definition
ARF, inj site rxn
Term
Magnevist drug interactions
Definition
none listed
Term
Magnevist side effects
Definition
HA, nausea, inj site coldness, DZ
Term
Magnevist Blackbox warning
Definition
Inc risk of nephrogenic systemic fibrosis (NSF) in renally impaired Pt.
Not for GFR<30
Term
Glucagon indication
Definition
insulin coma/severe hypoglycemia
Term
Glucagon dose
Definition
1mg inj
Term
Glucagon side effects
Definition
Nausea, vomiting
Term
Hydralazine brand name
Definition
Apresoline
Term
Apresoline generic name
Definition
Hydralazine
Term
Apresoline/hydralazine indication
Definition
HTN, vasodilation, CHF, pre-eclampsia, eclampsia
Term
Apresoline/hydralazine dose
Definition
5-200mg/d in 2-4 dose
Term
Apresoline/hydralazine drug interactions
Definition
NSAID, anti-inflammatory, diazoxide, anti-hypertensives, sympathomimetics
Term
Apresoline/hydralazine side effects
Definition
Rash, chest pain, blisters, lymph gland swelling, numbness, edema, SLE
Term
Normodyne generic name
Definition
Labetalol
Term
Labetalol brand name
Definition
Normodyne
Term
Normodyne/labetalol indication
Definition
HTN
Term
Labetalol dose
Definition
20mg then 40-80mg q 10min repeated inj or 200mg at rate of 2mg/min.
**keep in supine position
Term
Labetalol contraindications
Definition
Asthma, cadriac failure, 1st deg heartblock, cardiogenic shock, bradycardia, obstroctive airway disease
Term
labetalol warnings
Definition
hepatic inj, cardiac failure, ischemic heart disease, pheochromocytoma, DM, hypoglycemia, surgery
Term
Labetalol drug interactions
Definition
TCA, B-agonists, cimetidine, halothane, NTG
Term
Labetolol side effects
Definition
Postural hypotension, DZ, tingling of skalp/sking, nausea, inc BUN, fatigue
Term
Protamine indication
Definition
Heparin overdose also for LMWH
Term
Protamine dose
Definition
VERY slow IV inj 1mg/100USP unit of heparin or 1mg/1mg of enoxaparin
Term
What is the inj rate of protamine?
Definition
5mg/min
Term
Protamine warnings
Definition
asses for adequate blood volume
Term
Protamine side effects
Definition
Caused by too rapid drug admin
Bradycardia, hypotension, shock, dyspnea
Term
Nicardipine brand name
Definition
Cardene
Term
Cardene generic name
Definition
Nicardipine
Term
Cardene indication
Definition
Acute HTN tx when oral tx not pheasable
Term
Cardene doseing
Definition
20-40mg q8h
Term
Cardene/nicardipine contraindication
Definition
advanced aortic stenosis
Term
Cardene/nicardipine warnings
Definition
HF, angina, impaired hepatic fxn, renal impairment
not for use in small veins (VTE)
Term
Cardene drug interactions
Definition
Cimetidine, cyclosporine
Term
Nicardipine side effects
Definition
headache, hypotension, tachycardia, N/V
Term
Lexiscan generic name
Definition
Regadenoson
Term
Regadenoson brand name
Definition
Lexiscan
Term
Lexiscan/regadenoson indication
Definition
Radionuclide myocardial prefusion imagine (MPI) in pt unable to undergo exercise stress test
Term
Lexiscan/regadenoson dose
Definition
0.4mg/5ml rapid IV inj followed by saline flush and radiopharmaceutical
Term
Lexiscan/regadenoson contraindications
Definition
2nd or 3rd degree AV block
Sinuse node dysfxn *unless pacemaker*
Term
Lexiscan/regadenoson warnings
Definition
FATAL cardiac arrest, arrhythmia, MI, SA/AV blockade, bronchoconstriction
Term
Lexiscan/regadenoson drug interactions
Definition
methylxanthines, dipyridamole
Term
Lexiscan/regadenoson side effects
Definition
Dyspnea, HA, flushing, chest discomfort, DZ, angina, nausea
Term
Phentolamine brand name
Definition
Regitine
Term
Phentolamine/regitine indicaiton
Definition
HTN w/ phochromocytoma
Dx of pheochromocytoma
Dermal necrosis/sloughing
Term
Phentolamine/redosegitine
Definition
5mg IM/IV 1-2h prior to surg
Term
Phentolamine/regitine contraindiations
Definition
MI, coronary insuf, angina
Term
Phentolamine/regitine side effects
Definition
acute hypotensive episode, tachycardia, arrhythmia, DZ, flushing, orthostatic hypotension, nasal congestion, NVD
Term
Kayexalate generic name
Definition
Sodium Polystrene Sulfonate (SPS)
Term
SPS brand name
Definition
Kayexalate
Term
SPS indication
Definition
Hyperkalemia
Term
SPS dosing
Definition
(PO)15-40gm qd-qid
(Rectal) 50-100ml
Term
SPS contraindications
Definition
edematous conditions (CHF, HTN)
Term
SPS drug interactions
Definition
antacids, laxatives (may bind)
Term
SPS side effects
Definition
Fecal impaction, hypocalcemia, hypokalemia, Na retention
Term
which drugs might be used in PCI for various reasons?
Definition
Reopro, Argatroban, Bivalrudin
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