Term
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Definition
| •To prevent infection with Hib, a common cause of serious bacterial infections including meningitis in children younger than 5 yrs. |
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Term
Vaccines
Hepatitis B (Recombivax HB)Use? |
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Definition
| Routine immunization of children 6 week - 15 months ofage born to HBsAG-negative mother. |
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Term
Vaccines
Human Papillovavirus (HPV) (Gardasil)
Use? |
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Definition
| •Prevention of diseases caused by HPV types 6, 11, 16,18 (cervical, vaginal, vulvar cancer, genital warts in girls & women aged 9-26 yrs. |
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Term
Vaccines
Influenza (Fluzone)Use? |
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Definition
•Annual immunization of most people, especially children between 6mos-5yrs.
•Pregnant women
•People older than 50 years
•People who live in long term health care facilities
•People with chronic medical conditions(diabetes, lung disease, HIV/AIDS)
•People living with/caring for young children, nursing home residents, those w/ compromised immune systems or those with chronic medical conditions.
Contra: In people who are sensitive to egg protein, allergic reactions may ensue, such as hives, angioedema, asthma and anaphylaxis. |
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Term
Vaccines
Measles, Mumps & Rubella (MMR)Use? |
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Definition
•Immunization at 12-15 mo/2nd dose at 4-6 yrs.
Contra: In the UK, the MMR vaccine was the subject of controversy after publication of a 1998 paper by Andrew Wakefield et al. reporting a study of twelve children who had bowel symptoms along with autism or other disorders, including cases where onset was believed by the parents to be soon after administration of MMR vaccine |
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Term
Vaccines
Pneumococcal (Pneumovax)
Use |
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Definition
Adults with disorders associated with risk of pneumococcal infection(cardiovascular/pulmonary disease, diabetes, multip myeloma, cirrhosis, alcohol dependence, renal failure, immunosuppression
•Adults 65 yrs & older who are otherwise healthy
•Children 2 yrs & older with chronic disease associated with risk of pheumococcal infections (asplenia nephrotic syndrome immunosuppression).
Contra: Allergy to any parts of vaccine. |
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Term
Vaccines
Poliomyelitis (IPV)Use? |
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Definition
•Routine immunization of infants
•Immunization of adults not previously immunized and at risk of exposure(health care/laboratory workers)
Adverse: Allergy to vaccine or the antibiotics neomycin, streptomycin or polymyxin B, should not get polio vaccine. |
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Term
Vaccines
Rabies (RabAvert)Use? |
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Definition
•Pre-exposure immunization in people at high risk of exposure(vet’s, animal handlers)
•Postexposure prophylaxis in people who have been bitten by potentially rabid animals or who have skin scratches/abrasions exposed to animal saliva(animal licking of wound) urine or blood.
Contra: have a weakened immune system because of:
HIV/AIDS or another disease that affects the immune system,
treatment with drugs that affect the immune system, such as steroids,
cancer, or cancer treatment with radiation or drugs. |
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Term
Vaccines
Rotovirus (Rotateq)
Use |
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Definition
•Prevention of rotavirus gastroenteritis in infants.
Adverse: Babies with severe combined immunodeficiency” (SCID) should not get rotavirus vaccine. |
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Term
Vaccines
Varicella (Varivax)Use? |
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Definition
•Immunization of children 12 mo & older
•Immunization of adults
Adverse: Allergy to vaccine or antibiotic neomycin. |
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Term
Toxoids
Diphtheria, Tetanus & Pertussis (DTaP)
Use |
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Definition
•Immunization of children aged 6 wks-7 yrs
•Booster dose for person aged 10-18 yrs(Boostrix)
•Booster dose for person 11-64 yrs (Adacel)
Contra: Anyone who had coma, or long or multiple seizures within 7 days after a dose of DTP or DTaP should not get Tdap, |
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Term
Toxoids
Diphtheria & Tetanus (DT)
Use |
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Definition
•Routine immunization of infants & children 6 yrs & younger in whom pertussis vaccine is contraindication (those who have adverse reactions to initial does of DTaP vaccine.
Contra: Anyone who had a coma, or long or multiple seizures within 7 days after a dose of DTP or DTaP should not get Tdap, |
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Term
Toxoids
Tetanus Toxoid (TT)
Use |
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Definition
•Routine immunization of infants & young children.
•Primary immunizations of adults
•Prevention of tetanus in previously immunized people who sustain a potentially contaminated wound.
Contra: Allergy. HYPERSENSITIVITY TO ANY COMPONENT OF THE VACCINE, INCLUDING THIMEROSAL, A MERCURY DERIVATIVE, IS A CONTRAINDICATION FOR FURTHER USE OF THIS VACCINE. |
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Term
Immune Serums for Passive Immunity
Cytomegalovirus (CytoGam)Use? |
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Definition
•Prevention of CMV infection in heart, kidney, liver, lung, pancreas transplant recipients.
Contra: Allergy, Anaphylaxis. |
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Term
Immune Serums for Passive Immunity
Hepatitis B immune globulin (HBIG)Use? |
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Definition
•To prevent hepatitis after exposure. Neonates born to HBsAG-positive or unknow-status mothers are given HBIG and the first dose of Hep B vaccine with 12 hrs of birth.
Contra: Anyone with a life-threatening allergy to yeast, or to any other component of the vaccine, should not get hepatitis B vaccine. Tell your provider if you have any severe allergies. Anyone who has had a life-threatening allergic reaction to a previous dose of hepatitis B vaccine should not get another dose. Anyone who is moderately or severely ill when a dose of vaccine is scheduled should probably wait until they recover before getting the vaccine. |
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Term
Immune Serums for Passive Immunity
Immune globulin (IGIM)Use? |
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Definition
•To decrease the severity of Hep A, measles, and varicella after exposure.
•To treat immunoglobulin deficiency.
Contra: Allergy, anaphylaxis (rare). |
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Term
Immune Serums for Passive Immunity
Respiratory syncyial virus (RespiGam)
Use? |
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Definition
•Prevention of serious RSV infections in high risk children less than 2 yrs old(bronchopulmonary dysplasia/history of premature birth(gestation of 35 wk or less)
•Treatment of RSV lower respiratory tract infections in hospitalized infants & younger children,
Contra: Contraindicated in patients with deficiency of immune globulin and hypersensitivity. |
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Term
Immune Serums for Passive Immunity
Rh immune globulin (RhoGam)Use? |
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Definition
•To prevent sensitization in a subsequent pregnancy to the Rh(D) factor in an Rh-negative mother who has given birth to an Rh-positive infant by an Rh-positive father.
Contra: Prior hypersensitivity reaction to human immune globulin Rh[info](D)- or Du-positive patients. |
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Term
Immunostimulants
Epoetin alfa (Epogen, Procrit)choose the Actions, use & Side effects. |
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Definition
Action
•it stimulates erythropoiesis (increases red blood cell levels)
Use
•Prevention/treatment of anemia associated with chronic renal faliure or anticancer chemotherapy.
•Reduction of blood transfusions in anemic pts. Undergoing elective noncardiac, nonvascular surgery.
Side Effects
•Generally well tolerated. High blood pressure, headache, crippling cluster migraine (resistant to remedies), joint-pain and clotting at the injection site.
•Rare cases of stinging at the injection site, skin rash and flu-like symptoms (joint and muscle pain) have occurred within a few hours following administration.
•More serious side effects, including allergic reactions, seizures and thrombotic events (e.g., heart attacks, strokes, and pulmonary embolism) rarely occur |
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Term
Immunostimulants
Colony-stimulating factors |
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Definition
| Stimulate bone marrow blood cell production. |
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Term
Immunostimulants
Filgrastim (Neupogen)-WBC Use? |
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Definition
•To prevent infection in pts. Chemotherapy induced neutropenia/bone marrow transplantation.
•To mobilize stem cells from bone marrow to peripheral blood, where they can be collected and reinfused after chemotherapy that depresses bone marrow function.
• To treat severe chronic neutropenia.
Adverse effects
• mild-to-moderate bone pain after repeated administration and local skin reactions at the site of injection.
• Other adverse effects include spleen rupture, serious allergic reactions (including a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, and sweating), alveolar hemorrhage, acute respiratory distress syndrome (ARDS), and hemoptysis.
Contraindications
•Filgrastim should not be used in patients with known hypersensitivity to E. coli-derived proteins |
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Term
Immunostimulants
Sargramostim (Leukine)-WBC
Use |
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Definition
•After bone marrow transplantation to promote bone marrow function or to treat graft failure or delayed function.
•Mobilization of stem cells in peripheral blood so they can be collected.
•Acute myeloid leukemia, Crohn’s disease, GI inflammatory disorders
Contraindications
•Sargramostim should not be used in patients with excessive leukemic myeloid blasts in the bone marrow or peripheral blood (≥ 10%), in patients with known hypersensitivity to GM-CSF, yeast-derived products or any component of the product and for concomitant use with chemotherapy and radiotherapy. |
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Term
Immunosuppresants
Adalizumab (Humira) |
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Definition
Action
•Adalimumab is a TNF blocker. It works by blocking a protein (TNF-alpha) found in the body that causes inflammation.
Use
•Rheumatoid arthritis, Crohn’s disease(moderate to severe)
•Treating a variety of moderate to severe inflammatory conditions (eg, rheumatoid arthritis, juvenile idiopathic arthritis [JIA], psoriatic arthritis, ankylosing spondylitis).
•ulcerative colitis, or chronic plaque psoriasis.
Contraindicated in:
•you are allergic to any ingredient in adalimumab
•you have a severe infection (eg, sepsis) or any other active infection
•you are using abatacept, anakinra, or another TNF blocker (eg, certolizumab, etanercept, infliximab
Pharmacokinetics
Absorption
•Bioavailability 64% (subcutaneous), 0% (oral)
Elderly
•In patients with rheumatoid arthritis (RA), there was a trend toward lower Cl with increasing age in patients 40 to older than 75 y.
Children
•In children 4 to 17 y of age with juvenile idiopathic arthritis, mean steady-state trough serum adalimumab concentrations were 6.8 and 6.6 mcg/mL for children receiving adalimumab 20 or 40 mg, respectively, every other week as monotherapy. |
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Term
Immunosuppresants
Basiliximab (Simulect) |
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Definition
•It is used to prevent rejection in organ transplantation, especially in kidney transplants
•Basiliximab is a chimeric anti-intcrleukin-2 receptor monoclonal antibody.
•Basiliximab is a glycoprotein produced by recombinant technology.
•It specifically binds to and blocks the alpha chain of interleukin-2 receptors (IL-2R alpha), also known as CD25 antigen, on the surface of activated T-lymphocytes.
•Due to its monoclonal nature it provides safer and more predictable therapeutic, that is, immunosuppressive response of the polyclonal antibodies.
Adverse Effects
•The most common adverse effects in adult patients are constipation, infections, pain, nausea, peripheral oedema, hypertension, anaemia, headache, hyperkalacmia, hypercholesterolemia, increase in serum creatinine, and hypophosphataemia. |
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Term
Immunosuppresants
Cyclosporine (Sandimmune) |
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Definition
Action:
•Prevent rejection of solid organ(heart, kidney, liver) transplant.
•Inhibits normal immune responses (cellular and humoral) by inhibiting interleukin-2, a factor necessary for initiation of T-cell activity. Therapeutic Effects: Prevention of rejection reactions. Slowed progression of rheumatoid arthritis or psoriasis.
Use
•PO, IV: Prevent rejection of solid organ(heart, kidney, liver) transplant.
•PO: Treatment of severe active rheumatoid arthritis (Neoral only). Treatment of severe recalcitrant psoriasis in adult nonimmunocompromised patients (Neoral only).
•Prevent/treat graft-versus-host(DVHD-disease in bone marrow/stem cell transplantation.
•Psoriasis
•Rheumatoid arthritis
Pharmacokinetics
Absorption:
•Erratically absorbed (range 10–60%) after oral administration, with significant first-pass metabolism by the liver. Microemulsion (Neoral) has better bioavailability.
Distribution:
•Widely distributed, mainly into extracellular fluid and blood cells. Crosses the placenta; enters breast milk. Protein Binding: 90–98%.
Metabolism and Excretion:
•Extensively metabolized by the liver (first pass); excreted in bile, small amounts excreted unchanged in urine.
Contraindicated in:
•Hypersensitivity to cyclosporine or polyoxyethylated castor oil (vehicle for IV form)
•OB/Lactation: Should not be given unless benefits outweigh risks
•Disulfiram therapy or known alcohol intolerance (IV and oral liquid dose forms contain alcohol)
•Psoriasis patients receiving immunosuppressants or radiation; Uncontrolled hypertension.
Use Cautiously in:
•Severe hepatic impairment (dose ↓ recommended); Renal impairment (frequent dose changes may be necessary); Active infection;
•Pedi: Larger or more frequent doses may be required.
Adverse Reactions/Side Effects
•(CNS: SEIZURES, tremor, confusion, flushing, headache, psychiatric problems.
•CV: hypertension.
•GI: diarrhea, hepatotoxicity, nausea, vomiting, abdominal discomfort, anorexia, pancreatitis.
•GU: nephrotoxicity.
•Derm: hirsutism, acne. F and E hyperkalemia, hypomagnesemia.
•Hemat: anemia, leukopenia, thrombocytopenia.
•Metab: hyperlipidemia, hyperuricemia.
•Neuro: hyperesthesia, paresthesia.
•Misc: gingival hyperplasia, hypersensitivity reactions, infections (including activation of latent viral infections such as BK virus-associated nephropathy). |
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Term
Immunosuppresants
Etanercept (Enbrel) |
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Definition
Action
•Tumor necrosis factor (TNF) is a substance made by your body's immune system. People with inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis have too much TNF in their bodies. ENBREL reduces levels of the active form of TNF.
Use
•Rheumatoid arthritis
oENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderate to severe rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone
•Psoriatic arthritis
oENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with psoriatic arthritis. ENBREL can be used in combination with methotrexate in patients who do not respond adequately to methotrexate alone.
•Ankylosing spondylitis
oENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.
•Juvenile chronic arthritis
oENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in children ages 2 years and older.
Side Effects
•ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.
Common side effects include: Injection site reactions, upper respiratory infections (sinus infections), and headache. |
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Term
Immunosuppresants
Infliximab (Remicade) |
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Definition
•Goal: of treating moderately to severely active Crohn’s disease, in patients who have not responded well enough to other therapies, with REMICADE® (infliximab)?
•REMICADE® goes beyond temporary relief of symptoms and provides lasting remission.
•Clinical studies have demonstrated that REMICADE® helps eliminate steroid use and helps heal the intestinal lining.
Use
•Crohn’s disease
•Rheumatoid arthritis
•Psoriasis
Side effects: serious (sometimes fatal) side effects have been reported in people taking REMICADE®.
•Infections (like TB, blood infections, pneumonia)—fever, tiredness, cough, flu, or warm, red or painful skin or any open sores. REMICADE® can make you more likely to get an infection or make any infection that you have worse.
•Lymphoma, or any other cancers in adults and children.
•Heart failure—new or worsening symptoms, such as shortness of breath, swelling of your ankles or feet, or sudden weight gain.
•Reactivation of HBV—feeling unwell, poor appetite, tiredness, fever, skin rash and/or joint pain.
•Liver injury—jaundice (yellow skin and eyes), dark brown urine, right-sided abdominal pain, fever, or severe tiredness.
•Blood disorders—fever that doesn’t go away, bruising, bleeding or severe paleness.
•Nervous system disorders—numbness, weakness, tingling, changes in your vision or seizures.
•Allergic reactions during or after the infusion—hives, difficulty breathing, chest pain, high or low blood pressure, swelling of face and hands, and fever or chills.
•Lupus-like syndrome—chest discomfort or pain that does not go away, shortness of breath, joint pain, rash on the cheeks or arms that gets worse in the sun. The more common side effects with REMICADE® are respiratory infections (that may include sinus infections and sore throat), headache, rash, coughing and stomach pain.
•Psoriasis—new or worsening psoriasis such as red scaly patches or raised bumps on the skin that are filled with pus. |
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Term
Immunosuppresants
Tacrolimus (Prograf) |
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Definition
Action
•Inhibits T-lymphocyte activation. Therapeutic Effects: Prevention of transplanted organ rejection.
Use
•Prevention of organ rejection in patients who have undergone allogenic liver, kidney, or heart transplantation (used concurrently with corticosteroids).
Pharmacokinetics
Absorption:
•Absorption following oral administration is erratic and incomplete (5–67%).
Distribution:
•Crosses the placenta and enters breast milk. Protein Binding: 99%.
Metabolism and Excretion:
•99% metabolized by the liver; <1% excreted unchanged in the urine.
Contraindications/Precautions
•Hypersensitivity to tacrolimus or to castor oil (a component in the injection); Lactation: Enters breast milk posing risk to fetus.
Use Cautiously in:
•Renal or hepatic impairment (dosage reduction may be required; if oliguria occurs, wait 48 hr before initiating tacrolimus); Concurrent use with cyclosporine should be avoided; Exposure to sunlight/UV light (may ↑risk of malignant skin changes); OB: Hyperkalemia and renal impairment may occur in the newborn; use only if benefit to mother justifies risk to the fetus.
Adverse Reactions/Side Effects
•CNS: SEIZURES, dizziness, headache, insomnia, tremor, abnormal dreams, agitation, anxiety, confusion, emotional lability, depression, hallucinations, psychoses, somnolence. EENT: abnormal vision, amblyopia, tinnitus.
•Resp: cough, pleural effusion, asthma, bronchitis, pharyngitis, pneumonia, pulmonary edema.
•CV: hypertension, peripheral edema, QTc prolongation.
•GI: GI BLEEDING, abdominal pain, anorexia, ascites, constipation, diarrhea, dyspepsia, increased liver function studies, nausea, vomiting, cholangitis, cholestatic jaundice, dysphagia, flatulence, increased appetite, oral thrush.
•GU: nephrotoxicity, urinary tract infection.
•Derm: pruritus, rash, alopecia, herpes simplex, hirsutism, sweating, photosensitivity.
•Endo: hyperglycemia. F and E hyperkalemia, hyperlipidemia, hypokalemia, hypomagnesemia, hypophosphatemia, hyperphosphatemia, hyperuricemia, hypocalcemia, hyponatremia, metabolic acidosis, metabolic alkalosis.
•Hemat: anemia, leukocytosis, leukopenia, thrombocytopenia, coagulation defects. MS: arthralgia, hypertonia, leg cramps, muscle spasm, myalgia, myasthenia, osteoporosis.
•Neuro: paresthesia, neuropathy.
•Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS, fever, generalized pain, abnormal healing, chills, increased risk of lymphoma/skin cancer |
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Term
Ocologcal drugs/ Alkylating Agents
Cyclophosphamide (Cytoxan) |
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Definition
Mechanism of action
•The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low levels of ALDH.
•Phosphoramide mustard forms DNA crosslinks both between and within DNA strands at guanine N-7 positions (known as interstrand and intrastrand crosslinkages, respectively). This is irreversible and leads to cell death.
•Cyclophosphamide has relatively little typical chemotherapy toxicity as ALDHs are present in relatively large concentrations in bone marrow stem cells, liver and intestinal epithelium. ALDHs protect these actively proliferating tissues against toxic effects of phosphoramide mustard and acrolein by converting aldophosphamide to carboxyphosphamide that does not give rise to the toxic metabolites phosphoramide mustard and acrolein
Use
•Cyclophosphamide is used to treat cancer and immune diseases;
•Hodgkin’s disease; non-Hodgkin’s lymphomas, leukemias, cancer of breast, lungs, ovaries tumors, multiple myeloma, neuroblastoma.
Pharmacokinetic data
Bioavailability; >75% (oral)
Metabolism; Hepatic
Excretion; Renal
Side effects
•Bone marrow depression, N&V, alopecia, hemorrhagic cystitis, hypersensitivity reactions, secondary leukemia/bladder cancer. |
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Term
Ocologcal drugs/ Antimetabolites
Fluorouracil (5-FU) |
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Definition
Use
•Carcinomas of the breast, colon, stomach, pancreas.
•Solar keratosis, basal cell carcinoma.
Side Effects
•Bone Marrow depression, N&V, mucositis, pain, pruritus, burning at site of application. |
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Term
Ocologcal drugs/Antimetabolites
Methotrexate (P) (MTX) |
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Definition
Use
•Effective against rapid growing tumors, and cancers
•Leukemias; non-Hodgkin’s lymphomas, osteosarcoma, choriocarcinoma of testes, cancers of breast, lung, head/neck.
•Take folic acid & Vit B12 supplements which can reduce homocysteine blood levels. Required by all pts.
Side Effects
•Bone Marrow, depression, N&V, muscositis, diarrhea, fever, alopecia(hair loss), ulceration of GI tract. |
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Term
Ocologcal drugs/ Antimetabolites
Doxorubicin (Adriamycin) |
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Definition
Use
•Acute leukemias; lymphomas, carcinomas of breast, lung, ovary.
Side Effects
•Bone marrow depression, alopecia, mucositis, GI upset, cardiomyopathy. Extravasation may lead to tissue necrosis. |
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Term
Ocologcal drugs/Taxanes
Docetaxel (Taxotere) |
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Definition
Use
•Advanced breast cancer, non-small cell lung cancer.
Side Effects
•Bone marrow depression, N&V, hypersensitivity reactions. |
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Term
Ocologcal drugs/ Vinca Alkaloids
Vincristine (Oncovin) |
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Definition
Use
•Hodgkin’s, lymphomas, acute leukemia, neuroblastoma, Wilms’ tumor
Side Effects
•Peripheral neuropathy.
•Extravasation may lead to tissue necrosis. |
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Term
|
Definition
Action
•Competes with estrogen for binding sites in breast and other tissues. Reduces DNA synthesis and estrogen response.
•Therapeutic Effects: Suppression of tumor growth. Reduced incidence of breast cancer in high-risk patients.
Use
•Adjuvant therapy of breast cancer after surgery and radiation (delays recurrence). Palliative or adjunctive treatment of advanced breast cancer. Prevention of breast cancer in high-risk patients. Treatment of ductal carcinoma in situ following breast surgery and radiation.
Pharmacokinetics
Absorption:
•Absorbed after oral administration.
Distribution:
•Widely distributed.
Metabolism and Excretion:
•Mostly metabolized by the liver. Slowly eliminated in the feces. Minimal amounts excreted in the urine
Contraindications/Precautions
•Hypersensitivity; Concurrent warfarin therapy with history of deep vein thrombosis (patients at high risk for breast cancer only)
•OB/Lactation: Pregnancy or lactation.
Use Cautiously in:
•↓ bone marrow reserve; Women with childbearing potential.
Adverse Reactions/Side Effects
•CNS: confusion, depression, headache, weakness.
•EENT: blurred vision.
•CV: PULMONARY EMBOLISM, STROKE, edema.
•GI: nausea, vomiting.
•GU: UTERINE MALIGNANCIES, vaginal bleeding. F and E hypercalcemia. Hemat: leukopenia, thrombocytopenia.
•Metab: hot flashes. MS: bone pain.
•Misc: tumor flare |
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Term
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Definition
Hib
Hepatitis B (Recombivax HB)
Human Papillovavirus (HPV) (Gardasil)
Influenza (Fluzone)
Measles, Mumps & Rubella (MMR)
Pneumococcal (Pneumovax)
Poliomyelitis (IPV)
Rabies (RabAvert)
Rotovirus (Rotateq)
Varicella (Varivax) |
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Term
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Definition
Diphtheria, Tetanus & Pertussis (DTaP)
Diphtheria & Tetanus (DT)
Tetanus Toxoid (TT) |
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Term
| Nmethe Immune Serums for Passive Immunity drugs? |
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Definition
Cytomegalovirus (CytoGam)
Hepatitis B immune globulin (HBIG)
Immune globulin (IGIM)
Respiratory syncyial virus (RespiGam)
Rh immune globulin (RhoGam) |
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Term
| What are the Immunostimulants drugs? |
|
Definition
Epoetin alfa (Epogen, Procrit)
Filgrastim (Neupogen)
Sargramostim (Leukine) |
|
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Term
| What are the Immunosuppresants drugs? |
|
Definition
Adalizumab (Humira)
Basiliximab (Simulect)
Cyclosporine (Sandimmune)
Etanercept (Enbrel)
Infliximab (Remicade)
Tacrolimus (Prograf) |
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Term
| What are the Oncological drugs? |
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Definition
Cyclophosphamide (Cytoxan)
Fluorouracil (5-FU)
Methotrexate (P) (MTX)
Doxorubicin (Adriamycin)
Docetaxel (Taxotere)
Vincristine (Oncovin)
Tamoxifen |
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