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Details

Drug list 2-a
Anti-coagulants, anti-platlets, respiratory drugs, GI drugs, opthalmic dyes
52
Pharmacology
Graduate
09/29/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

Amoxicillin

 

Clarithromycin

 

Metronidazole

 

Tetracycline

Definition
antimicrobial agent used in treating H.pylori
Term

Bismuth compounds

 

(petpo-bismol, Kaopectate)

Definition
antimicrobial agent
Term

Cimetidine

 

Definition

H2- histamine receptor blocker

 

decrease acid secretion

 

can cause headache, dizzyness, diarrhea

Term
Famotidine
Definition

H2- histamine receptor blocker

 

decrease acid secretion

 

can cause headache, dizzyness, diarrhea

Term
Nizatidine
Definition

H2- histamine receptor blocker

 

decrease acid secretion

 

can cause headache, dizzyness, diarrhea

Term
Ranitidine
Definition

H2- histamine receptor blocker

 

decrease acid secretion

 

can cause headache, dizzyness, diarrhea

Term
Warfarin
Definition

Anticoagulants

 

Oral admin; interfere w/  synth. of vitK-dependent clotting factors

 

Decrease blood clotting, decrease thrombosis

Term
Pentoxifylline
Definition

improves blood flow through peripheral tissue

 

used for treatment of sickle cell anemeia

Term
Heparin
Definition

Anticouagulents

 

IV admin; Inhibit prothrombin->thrombin and fibrinogen->fibrin

 

Decrease blood clotting, decrease thrombosis

Term
Ardeparin
Definition

Anticouagulent

 

IV admin; Inhibit prothrombin->thrombin and fibrinogen->fibrin

 

Decrease blood clotting, decrease thrombosis

 

Term
Aspirin
Definition

Anitplatelets

 

prevent clots from forming in arteries by keeping platlets from binding

Term
Clopidogrel
Definition

Anitplatelets

 

prevent clots from forming in arteries by keeping platlets from binding

Term
Ticlopidine
Definition

Anitplatelets

 

prevent clots from forming in arteries by keeping platlets from binding

Term
Dipridamole
Definition

anit-platelets

 

impairs platelet function by inhibting the activitiy of adenosine deaminase and phosphodiesterase

Term

Streptokinase

 

Urokinase

Definition

Thrombolytic

 

prevent and treat excessive bleeding from surgical sights

 

disolved preformed clots

 

facilitate plasminogen to plasmin

Term
Cimetidine
Definition
H2- histamine antagonist
Term
Famotidine
Definition
H2- histamine antagonist
Term
Nizatidine
Definition
H2- histamine antagonist
Term
Ranitidine
Definition
H2- histamine antagonist
Term
Aluminum hydroxide
Definition

antacid (adsorbant)

 

neutralize intragastric HCl

 

can be used as an anti-diarrheal as well

Term
Calcium carbonate
Definition

antacid

 

neutralize intragastric HCl

Term
Magnesium hydroxide
Definition

antacid

 

neutralize intragastric HCl

Term
Sodium Bicarbonate
Definition

antacid

 

neutralize intragastric HCl

Term
Bismuth subsalicylate
Definition

mucosal protective agent

 

quick relief, reacts with protein in stomach to create barrier

Term
Sucralfate
Definition

mucosal protective agent

 

quick relief, reacts with protein in stomach to create barrier

Term
Misoprostol
Definition

prostoglandin

 

 

Term
Dicyclamine
Definition

anti-muscarinic

 

inhibits cholinergic system which inhibits gastric secretion

 

blocks M3R

Term
Omeprazole
Definition

PPI

 

Pro-drug under acidic conditions is protonated and converted to an active compound that reacts convalently with H+, K+-ATPase (thus longer duration)

Term
Esomeprazole
Definition

PPI

 

Pro-drug under acidic conditions is protonated and converted to an active compound that reacts convalently with H+, K+-ATPase (thus longer duration)

Term
Lansoprazole
Definition

PPI

 

Pro-drug under acidic conditions is protonated and converted to an active compound that reacts convalently with H+, K+-ATPase (thus longer duration)

Term
Pantoprazole
Definition

PPI

 

Pro-drug under acidic conditions is protonated and converted to an active compound that reacts convalently with H+, K+-ATPase (thus longer duration)

Term
Rabeprazole
Definition

PPI

 

Pro-drug under acidic conditions is protonated and converted to an active compound that reacts convalently with H+, K+-ATPase (thus longer duration)

Term

Castor oil

 

Senna

Definition

stimulant laxatives

 

hydrolyzed by lipase in the small intestine to ricinoleic acid

 

increases intestinal secretion, decreases glucose absorption, and stimulates colonic motor function

Term
Methylcellulose
Definition

bulk laxitives

 

form synthetic fibers for bacterial degradation that have to be exreted because they can not be absorbed

Term

Psyllium

 

 

Definition

bulk laxitives & used for constipation

 

fiber supplement, increases colonic residue, stimulating peristalsis

Term
Magnesium hydroxide
Definition

saline laxitive

 

draws water into the intestine along osmotic gradient

Term
Docusate
Definition

emulsifies stool

 

lowers surface tension allowing water to interact with stool

Term
Minerol Oil
Definition

Lubricant laxatives

 

lubricates the stool

Term

Lactulose

 

Sorbitol

Definition

Hyperosmolar agent

 

increases stool osmolarity

Term
Lubiprostone
Definition

Cl- channel activators

 

lubricates

Term
Polyethylene gylcol
Definition

Hyperosmolar agent

 

not metabolized by colonic bacteria

Term
Methycellulose
Definition

bulk laxitives & used for constipation

 

fiber supplement, increases colonic residue, stimulating peristalsis

Term
Bismuth subsalicylate
Definition

antidiarrheal

 

inhibits the formation of diarrhea-producing prostaglandins

 

modifies fluid and electrolyte transport

Term

Loperamide

 

 

Definition
antimotility agent (anti-diarrheal)
Term
Diphenoxlyate + atropine
Definition
antimotility agent (anti-diarrheal)
Term

Proparacaine

 

Petracaine

 

Benoxinate

Definition

local anesthetic eyedrops

 

Ester

Term

Lidocaine

 

Mepivacaine

 

Bupivacaine

Definition

anethetic eyedrops

 

Amides

Term
Rose bengal
Definition

stains ded or degenerated corneal and conjuctival cells

 

topical

Term
Lissamine green
Definition

stains ded or degenerated corneal and conjuctival cells

 

less painful

Term
Sodium flourescene
Definition

Topical stain corneal epithelial defects

 

includes a local anethsetic

Term
Indocyanine Green
Definition

flourescent dye for retinal and choroidal angiography

 

binds to plasma proteins

Term
Vertepofin
Definition
used with red light to creating free oxygen molecules which react with abnormal blood vessels and "burns them up"
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