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Drug effects and uses
Parasympathetic and sympathetic
20
Pharmacology
Graduate
12/08/2010

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Cards

Term
pilocarpine
Definition
-miosis, decrease intraocular pressure
-glaucoma
Term
metoclopramide (reglan)
Definition
-gastric emptying, anti-emetic (dopaR ag)
-gastroparesis, anti-emetic agent
Term
atropine
Definition
-dry mouth, constipation, urinary retention, dry skin, flush, bronchodilation, mydriasis, tachycardia, delirium (mad as hatter, red as beet, dry as bone)
-stop asystole, diarrhea, dilate pupils, antidote to AChE toxin
Term
scopolamine (l-hyoscine)
Definition
-motion sickness
Term
ipratropium (atrovent)
Definition
-bronchodilator for asthma and COPD
Term
neostigmine
Definition
-blocks AChE, prolongs parasymp effect
Term
sarin
Definition
-nerve gas poisoning (bronchial spasm-->death)
-chemical weapon
Term
pralidoxime
Definition
-treat inactivated AChE (given w/ atropine)
Term
epinephrine
Definition
-increase cardiac output and systolic arterial BP, increase O2 consumption and blood glucose
-stop anaphylactic response and code blue
Term
norepinephrine
Definition
-increase systolic and diastolic BP w/o effect on cardiac output and metabolism
-hypotensive shock
Term
dopamine
Definition
-renal failure w/ low perfusion (low dose, D1)
-first pressor in instances of chock (higher dose, alpha and beta R)
Term
phenylephrine
Definition
-vasoconstriction
-hypotension, nasal decongestant
Term
phenoxybenzamine
Definition
-pheochromacytoma (excess NE and Epi release from adrenal)
Term
dobutamine
Definition
-increases HR and force
-cardiomyopathy w/ congestive heart failure
Term
prazosin
Definition
-hypertension, enhance urine flow in BPH by blocking smooth muscle constriction
Term
clonidine
Definition
-decreases NE release pre-synaptically, reduce BP
-withdrawal in substance abuse
Term
isoproterenol
Definition
-stimulates cardiac output, dilates bronchial smooth muscle
Term
propranolol
Definition
-hypertension, angina, anxiety, vasovagal syncope, arrthythmias
Term
metoprolol
Definition
-reduce cardiac output
-hypertension and angina
Term
albuterol
Definition
-dilates bronchial and uterine smooth muscle, promotes glycogenolysis
-asthma and stop premature labor
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