Term
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Definition
Classification - antipsychotics
Therapeutic Action - Diminished signs and symptoms of psychoses
Usual disease Process - Acute and chronic psychotic disorders including schizophrenia, manic states, drug-induced psychoses, Tourette's syndrome
Side Effects - EPS reactions, blurred vision, dry eyes, constipation, dry mouth
Adverse Effects - NMS, AGRANULOCYTOSIS, SEIZURES |
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Term
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Definition
Classification - antidepressants
Therapeutic Action - Antidepressant action
Usual disease Process - Depression
Side Effects - lethargy, sedation, blurred vision, dry eyes, dry mouth, hypotension, constipation
Adverse Effects - SUICIDAL THOUGHTS, ARRHYTHMIAS |
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Term
| Prolixin Decanoate - fluphenazine |
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Definition
Classification - antipsychotics
Therapeutic Action - Diminished signs and symptoms of psychoses
Usual disease Process - Acute and chronic psychoses
Side Effects - EPS reactions, photosensitivity
Adverse Effects - NMS, AGRANULOCYTOSIS |
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Term
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Definition
Classification - antidepressants
Therapeutic Action - Antidepressant action that develops slowly over several weeks
Usual disease Process - Various forms of depression and enuresis in children
Side Effects - drowsiness, fatigue, blurred vision, dry eyes, constipation, dry mouth
Adverse Effects - ARRHYTHMIAS |
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Term
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Definition
Classification - antipsychotics, mood stabilizers
Therapeutic Action - Decreased symptoms of psychoses, bipolar mania, or autism
Usual disease Process - Schizophrenia in adults and adolescents age 13–17 yr
Short-term treatment of acute manic or mixed episodes associated with Bipolar I Disorder, Treatment of irritability associated with autistic disorder in children age 5–16
Side Effects - aggressive behavior, dizziness, EPS reactions, headache,increased dreams, increased sleep duration, insomnia, sedation, pharyngitis, rhinitis, visual disturbances, constipation, diarrhea, dry mouth, nausea, decreased libido, dysmenorrhea/menorrhagia, itching/skin rash
Adverse Effects - NMS, SUICIDAL THOUGHTS, AGRANULOCYTOSIS |
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Term
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Definition
Classification – antidepressants, SSRI (selective serotonin reuptake inhibitors)
Therapeutic Action - Antidepressant action, Decreased incidence of panic attacks, Decreased obsessive and compulsive behavior, Decreased feelings of intense fear, helplessness, or horror, Decreased social anxiety, Decrease in premenstrual dysphoria
Usual disease Process - Major depressive disorder, Panic disorder, Obsessive-compulsive disorder (OCD), Post-traumatic stress disorder (PTSD), Social anxiety disorder (social phobia), Premenstrual dysphoric disorder (PMDD)
Side Effects - dizziness, drowsiness, fatigue, headache, insomnia, diarrhea, dry mouth, nausea, sexual dysfunction, increased sweating, tremor
Adverse Effects - NMS, SUICIDAL THOUGHTS, SEROTONIN SYNDROME |
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Term
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Definition
Classification - antipsychotics, mood stabilizers
Therapeutic Action - Decreased manifestations of psychoses, depression, or acute mania
Usual disease Process – Schizophrenia, Depressive episodes with bipolar disorder, Acute manic episodes associated with bipolar I disorder (as monotherapy or with lithium or divalproex), Maintenance treatment of bipolar I disorder (with lithium or divalproex)
Side Effects - dizziness, weight gain
Adverse Effects - NMS, SEIZURES |
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Term
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Definition
Classification - antipsychotics, mood stabilizers
Therapeutic Action - Decreased manifestations of schizophrenia, Decreased mania in bipolar patients, Decreased symptoms of depression, Decreased agitation associated with schizophrenia or bipolar disorder, Decreased emotional and behavioral symptoms of irritability
Usual disease Process – Schizophrenia, Acute and maintenance therapy of manic and mixed episodes associated with bipolar disorder, Adjunctive treatment of depression in adults, Agitation associated with schizophrenia or bipolar disorder, Irritability associated with autistic disorder in children
Side Effects - drowsiness, EPS reactions, constipation, tremor
Adverse Effects - SUICIDAL THOUGHTS, AGRANULOCYTOSIS, NMS |
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Term
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Definition
Classification - antidepressants, selective serotonin norepinephrine reuptake inhibitors
Therapeutic Action - Decreased depressive symptomatology, Decreased neuropathic pain, Decreased symptoms of anxiety, Decreased pain
Usual disease Process - Major depressive disorder, Diabetic peripheral neuropathic pain, Generalized anxiety disorder, Fibromyalgia, Chronic musculoskeletal pain (including chronic lower back pain and chronic pain from osteoarthritis)
Side Effects - fatigue, drowsiness, insomnia, decreased appetite, constipation, dry mouth, nausea, dysuria, increased sweating
Adverse Effects - NMS, SEIZURES, SUICIDAL THOUGHTS, HEPATOTOXICITY, SEROTONIN SYNDROME |
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Term
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Definition
Classification - analgesic adjuncts, antianxiety agents, sedative/hypnotics, benzodiazepines
Therapeutic Action – Sedation, Decreased anxiety, Decreased seizures
Usual disease Process - Anxiety disorder (oral), Preoperative sedation (injection), Decreases preoperative anxiety and provides amnesia
Side Effects - dizziness, drowsiness, lethargy,
Adverse Effects - APNEA, CARDIAC ARREST |
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Term
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Definition
Classification – antidepressants, antianxiety agents
Therapeutic Action – Decrease in depressive symptomatology, with fewer relapses/recurrences, Decreased anxietyDecrease in panic attacks
Usual disease Process – Major depressive disorder, Generalized anxiety disorder (Effexor XR only), Social anxiety disorder (Effexor XR only), Panic disorder (Effexor XR only)
Side Effects - abnormal dreams, anxiety, dizziness, headache, insomnia, nervousness, weakness, rhinitis, visual disturbances, abdominal pain, altered taste, anorexia, constipation, diarrhea, dry mouth, dyspepsia, nausea, vomiting, weight loss, sexual dysfunction, ecchymoses, paresthesia,
Adverse Effects - NMS, SEIZURES, SUICIDAL THOUGHTS, SEROTONIN SYNDROME |
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Term
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Definition
Generic & Trade Name
alprazolam/xanax
Classification
antianxiety agents
Therapeutic Action
CNS Depression
Usual disease Process
Person is manic/anxious
Side Effects
dizziness, drowsiness, lethargy, confusion, hangover, headache, mental depression, paradoxical excitation.
Adverse Effects
physical dependence, psychological dependence, tolerance. |
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Term
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Definition
Generic & Trade Name
buPROPion, Budeprion XL, Wellbutrin
Classification
aminoketones
Therapeutic Action
Antidepressant
Decreased reabsorption of dopamine in CNS
Usual disease Process
Used for chronic depression
Side Effects
agitation, headache, depression, hostility, insomnia, mania, psychoses.
Adverse Effects
SEIZURES, SUICIDAL THOUGHTS/BEHAVIOR, |
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Term
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Definition
Generic & Trade Name
clonazepam, Klonopin
Classification
anticonvulsants
Therapeutic Action
Stimulates inhibitory GABA receptors causing sedation
Reduces panic/mania
Usual disease Process
Episodes of mania/ panic
Side Effects
behavioral changes,drowsiness, fatigue, slurred speech, ataxia, sedation
Adverse Effects
SUICIDAL THOUGHTS |
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Term
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Definition
Generic & Trade Name
Chlordiazepoxide mitran, Librium
Classification
Antianxiety/sedative/hypnotic
Therapeutic Action
• Acts at many levels of the CNS to produce anxiolytic effect
• Depresses the CNS, probably by potentiating GABA, an inhibitory neurotransmitter
Usual disease Process
Periods of heightened stress, inability to sleep
Side Effects
dizziness, drowsiness, hangover, headache, mental depression, paradoxical excitation, sedation
Adverse Effects
physical dependence, psychological dependence, tolerance. |
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Term
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Definition
Generic & Trade Name
busPIRone, BuSpar
Classification
Antianxiety
Therapeutic Action
Binds to serotonin and dopamine receptors in the brain
Usual disease Process
Episodes of heightened stress
Side Effects
dizziness, drowsiness, excitement, fatigue,headache, insomnia, nervousness, weakness,
Adverse Effects
tachycardia, hypertension, hypotension, syncope. |
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Term
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Definition
Generic & Trade Name
phenelzine, Nardil
Classification
Antidepressant
Therapeutic Action
Inhibits the enzyme monoamine oxidase, resulting in an accumulation of various neurotransmitters (dopamine, epinephrine, norepinephrine, and serotonin) in the body
Usual disease Process
Chronic depression
Side Effects
dizziness, drowsiness, fatigue,headache, hyperreflexia, insomnia, tremor,twitching, weakness,
Adverse Effects
SEIZURES, HYPERTENSIVE CRISIS |
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Term
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Definition
Generic & Trade Name
Lithobid, Lithium
Classification
Mood stabilizer
Therapeutic Action
Alters cation transport in nerve and muscle
• May also influence reuptake of neurotransmitters
Usual disease Process
Episodes of mania and depression
Side Effects
fatigue, headache, impaired memory, ataxia, sedation, confusion, dizziness,
Adverse Effects
seizures |
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Term
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Definition
Generic & Trade Name
Valproates, Depakote
Classification
Anticonvulsants
Therapeutic Action
Increase levels of GABA, an inhibitory neurotransmitter in the CNS
Usual disease Process
Over excited neurotransmitters cause convulsions/mania
Side Effects
agitation, dizziness,headache, insomnia, sedation, confusion, depression.
Adverse Effects
SUICIDAL THOUGHTS, HEPATOTOXICITY, PANCREATITIS HYPERAMMONEMIA. HYPERAMMONEMIA. |
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Term
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Definition
Generic & Trade Name
Lamotrigine, Lamictal
Classification
Anticonvulsants
Therapeutic Action
Stabilizes neuronal membranes by inhibiting sodium transport
Usual disease Process
Over stimulated neurons cause mania/convulsions
Side Effects
ataxia, dizziness, headache, nausea, vomiting.
Adverse Effects
ASEPTIC MENINGITIS, SUICIDAL THOUGHTS, STEVENS-JOHNSON SYNDROME. |
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Term
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Definition
Generic & Trade Name
Donepezil, Aricept
Classification
Anti-alzheimer’s agent
Therapeutic Action
Inhibits acetylcholinesterase thus improving cholinergic function by making more acetylcholine available
Usual disease Process
Not enough acetylcholine available reduces memory function
Side Effects
headache, abnormal dreams, depression, dizziness, drowsiness, fatigue, insomnia, syncope,
Adverse Effects
sedation (unusual). weight gain (unusual) |
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Term
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Definition
Generic & Trade Name
Memantine, Namenda
Classification
Anti-Alzheimer agent
Therapeutic Action
Anti-Alzheimer agent
Binds to CNS N-methyl-D-aspartate (NMDA) receptor sites, preventing binding of glutamate, an excitatory neurotransmitter
Usual disease Process
Not enough acetylcholine available reduces memory function
Side Effects
dizziness, fatigue, headache, sedation.
Adverse Effects
hypertension |
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