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Drug Cards
Drug Cards
38
Pharmacology
Professional
09/30/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

Formoterol

 

 

 

 

Onset:  15 min

Peak: 30-60

Duraction: 12 hr

Definition

Trade Name: Foradil

Indication: athma - COPD- bronchospasm

Contraindication: tachycardia, heart arrthmia

Side effects: tremors, hypertension, headache, tachycardia

Dosage: 12 mcg/ blister bid

Category: saligenin, LABA-sympthomimetic

Receptor: B2

Route: DPI

 

Term

Albuterol/Atrovent

 

 

 

 


 

 

 

 

 

Definition

Trade Name:  Combivent

Indication: bronchospasm

Contraindication: hypersensitivity to combvient, atropine, soybeans, & peanuts

Side effects: tachycardia, tremors

Dosage: mutliple types (2.5mg / 0.5mg)

Category: combination meds

Receptor: B2

Route: MDI (Combivent) - DuoNeb (SVN)

 

Term

Levalbuterol

 

 

 

 

Onset: 15 min

Peak: 30-60 min

Duration: 5-8 hr

Definition

Trade Name: Xopenex, Xopenex HFA

Indication: wheezing, SOB, chronic bronchitis, lung diseases

Contraindication: chest pain, tachycardia, heart arrhythmia

Side effects: tremor, nervousness, dizziness, weakness, headache,   nausea, insomnia

Dosage: SVN: 1.25mg tid

             MDI: 45µg/puff, 2 puffs q4-6

Category: SABA bronchodilator

Receptor: preference B2

Route: MDI, SVN

Term

Ipratropium bromide

 

 

 

 

 

 

 

Onset: 15 min

Duration: 1-2 hrs

Peak effect: 4-6 min

Definition

Trade Name: Atrovent MDI

Indication: anticholonergic (dry up mucus), bronchodilator

Contraindication: bronchospasms

Side effects: cough,palpitation, anxiety, headache, bronchospasms

Dosage: MDI: 18mcg/puff, 2 puffs qid

             SVN: 0.5 mg qid

Category: anticholonergic

Receptor: muscarinic

Route: MDI

Term
Tiotropium bromide
Definition

Trade Name: Spiriva

Indication: bronchospams, COPD, chronic bronchitis, emphysema

Contraindication: hypersensitivity to tiotropium, or ipotropium

Side effects: cough, tachycardia, chest pain, palpation

Dosage: 18 µg/inhalation

Category: anticholonergic

Receptor: M1, M2, M3

Route: DPI

Term

Albuterol

 

 

 

 

Onset: 15 min

Peak: 30-60 min

Duration: 5-8 hr

 

Definition

Trade Name: Proventil, Ventolin, Proair, Accuneb

Indication: wheezing, SOB, chronic bronchitis, lung disease

Contraindication: chest pain, tachycardia, heart arrhythmia

Side effects: tremor, nervousness, dizziness, weakness, headache, nause, insomnia

Dosage: SVN: 2.5mg tid/qid

             MDI: 90 µg/puff, 2 puffs tid/qid

Category: SABA, bronchodilator

Receptor: B2

Route: MDI, tab, syrup, SVN

Term

Pirbuterol

 

 

 

 

Onset: 5 min

Peak: 30 min

Duration: 5 hr

Definition

Trade Name: Maxair auto-inhaler

Indication: wheezing, SOB, chronic bronchitis, lung diseases

Contraindication: chest pain, tachycardia, heart arrhythmia

Side effects: tremor, nervousness, dizziness, weakness, headache, nausea, insomnia

Dosage: MDI: 200 µg/puff, 2 puffs q4-6hrs

Category: SABA, Saligens

Receptor: B2

Route: MDI

Term

Salmeterol

 

 

 

 

Onset: 20 min

Peak effect: 3-5 hrs

Duration: 12 hrs

Definition

Trade Name: Servent

Indication: asthma attacks, bronchospasms

Contraindication: tachycardia, heart arrythmia

Side effects: tremors, tachycardia, dysrythmias, anxiety,

                   hypertension

Dosage: 50 mcg blister via bid

Category: LABA, saligenin, sympathomimetic

Receptor: B2

Route: MDI, DPI

Term

Metaproterenol

 

 

 

 

 

Onset:1-5 min

Peak: 30-60 min

Duration: 4-6 hrs

Definition

Trade Name: Alupent, Metaprel

Indication: asthma, bronchospasms, COPD

Contraindication: hypertension, tachycardia

Side effects: hypertension, headache, hypokalmia, tremor

Dosage: SVN: 15 mg

            MDI: discontinued

Category: Resorcinols

Receptor: B2

Route: SVN

Term
Arformoterol
Definition

Trade Name: Brovana

Indication: bronchospasms, COPD, emphysema

Contraindication: bronchospasms, tachycardia, hypertension, hypokalemia

Side effects: bronchospasms, tachycardia, headache, dizziness,

                      tremors, nausea, wheezing hyper/hpokalemia,

                      hyper/hypotension

Dosage: 15 µg, bid

Category: LABA, saligenins

Receptor: B2

Route: SVN

Term

Epinephrine

 

 

 

 

 

 

 

Duration: less than 3 hrs

Definition

Trade Name: Adrenalin, Epi Pen

Indication: bronchospasm, asthma, shock, cardiac arrest

Contraindication: closed angle glaucoma, labor, shock, sulfite

                            hypersensitivity

Side effects: tachycardia, increased BP, tremor, headache, insomnia

Dosage: 0.3mg 1:1000 SQ

              0.3 mg 1:1000 IM

Category: Catecholaines, ultra-short acting

Receptor: alpha & B2

Route: Injection

Term

Racemic Epinephrine

 

 

 

 

 

 

 

 

Duration: less than 3 hrs

Definition

Trade Name: MicroNefrin

Indication: bronchospasm, asthma, shock, cardiac arrest, reduce airway

                   swelling

Contraindication: closed angle glaucoma, labor, shock, sulfite hypersensitivity

Side effects: tachycardia, cardia dysrhythmia, sweating, paradoxical

                     bronchospasms

Dosage: SVN: 0.25- 0.5ml 2.25% solution

Category: Catecholaines

Receptor: alpha & B2

Route: SVN

Term

Terbutaline sulfate

 

 

 

 

 

 

 

Onset: 5-30 min

Duration: 3-6 hrs

Peak effect: 30-60 min

Definition

Trade Name: Terbutalin

Indication: asthma, bronchospasms, COPD

Contraindication: hypertension, tachycardia

Side effects: hypertension, headache, hypokalmia, dyspnea, nausea, tremor,

                      anxiety

Dosage: 0.25 SQ

Category: Resorcinols, SABA

Receptor: B2

Route: Injection, tablet

Term
Theophylline
Definition

Trade Name: Slo-Phyllin, Theolair, TheoDur, Theo-bid

Indication: asthma -COPD- chronic bronchitis-

                     emphysema

Contraindication: hypersensitivity of xanthenes- tachydysrythmias

Side effects: tachypnea, pals, hypertension

Dosage: tablets, syrup, injection, ER tablet 

Category: methylxanthine

Receptor: phosphodiesterase (PDE)

Route: oral injection

Term
Ciclesonide
Definition

Trade Name:  Alvesco

Indication: nasal congestion, asthma, allergic rhinitis

Contraindication: bronchospasms

Side effects: cough, nasal congestion, bronchospasms, headache, back pain

Dosage: 80 mcg or 160 mcg

Category: inhaled corticosterioid

Receptor:

Route:  MDI

Term
Triamcinolone Acetonide
Definition

Trade Name:  Azmacort

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation

Contraindication: acute bronchospasms, fungal infections

Side effects: weight gain/lose, cough, hyperglycemia, hypokalmia, hypotension

Dosage:

Category: inhaled corticosteroids

Receptor:

Route: MDI 

Term
Cromolyn Sodium
Definition

Trade Name: Intal

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids

Contraindication: acute bronchospasms, arrhythmias, renal disease, renal failure

Side effects: nause, cough, abdominal pain, brochospasm, nasal irritation

Dosage:

Category: anti-asthmatic agent

Receptor:

Route: MDI 

Term
Nedocromil Sodium
Definition

Trade Name: Tilade

Indication: prophylactic agent indicated in the management of patients with bronchial asthma. allergic conjunctivitis

Contraindication: acute bronchospasms

Side effects: nausea, cough, abdominal pain, brochospasm, nasal congenstion, vomiting

Dosage:

Category: anti-asthmatic agent

Receptor:

Route: SVN 

Term
Beclomethason dipropionate HFA
Definition

Trade Name: QVAR

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids

Contraindication: status asthmaticus

Side effects: nausea, cough, bronchospasms, nasal dryness/irritation

Dosage: 40 to 80 mg/ puff bid or 40 to 160 mg/ bid, children 40 to 80 mg/bid

Category: inhaled corticosterioids

Receptor:

Route: MDI 

Term
Flunisolide Propionate
Definition

Trade Name: AeroBid, AeroBid-M

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids. allergic rhinitis, asthma

Contraindication: status asthmaticus, infection

Side effects: nausea, cough, bronchospasms, nasal dryness/irritation

Dosage:

Category: inhaled corticosterioids

Receptor:

Route: DPI, SVN

Term
Budesonide
Definition

Trade Name: Pulmicort Trubuhaler, Pulmicort Respules

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids. asthma, allergic rhinitis, croup, bronchospasms

Contraindication: status asthmaticus

Side effects: nausea, cough, bronchospasms,

Dosage: 200 mcg, (0.25mg/ml, 0.5mg/ml, 1 mg/ml: Respules)

Category: inhaled corticosterioids

Receptor:

Route: DPI, SVN

Term
Fluticasone Propionate/ Salmeterol
Definition

Trade Name: Advair Diskus/ Advair HFA

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids. asthma, COPD

Contraindication: status asthmaticus, acute bronchospasms

Side effects: nausea, cough, bronchospasms, tremors, wheezing

Dosage:

Category: combination

Receptor:

Route: DPI, MDI 

Term
Mometasone Furoate
Definition

Trade Name: Asmanex Twist haler

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids. allergic rhinitis

Contraindication: status asthmaticus, milk protein hypersensitivity

Side effects: nausea, cough, bronchospasms, abdominal pain, dyspnea, fever

Dosage:

Category: inhaled corticosterioids

Receptor:

Route: DPI 

Term
Fluticasone
Definition

Trade Name: Flovent HFA, Flovent Diskus

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids. asthma, COPD, allergic rhinitis

Contraindication: status asthmaticus, acute bronchospasms

Side effects: nausea, cough, bronchospasms, weight gain

Dosage:

Category: inhaled corticosterioids

Receptor:

Route: DPI, MDI 

Term
Budesonid / Formoterol Furmarate HFA
Definition

Trade Name: Symbicort

Indication: long term prevention of symptoms, suppression, control, and reversal of inflammation. reduce need for oral corticosteroids. asthma, COPD

Contraindication: status asthmaticus, acute bronchospasms

Side effects: nausea, cough, bronchospasms, nasal congestion, abdominal pain.

Dosage:

Category: combination drug

Receptor:

Route: MDI

Term
Pentamidine isethionate
Definition

Trade Name: NebuPen

Indication: Pneumocystis pneumonia

Contraindication: anemia, dehydration, hypoglycemia, hyperglycemia, hypotension

Side effects: cough, fatigue, nausea, bronchospasms

Dosage: 300 mg

Category: Anti-infective agent

Receptor:

Route: SVN

 

Term
Ribovirin
Definition

Trade Name: Virazole

Indication: hepatitis C, RSV, SARS

Contraindication: sickle cell disease, hepatitis, anemia

Side effects: dehydration, dyspnea, fatigue, nausea, weight loss

Dosage: 6g

Category: anti-infective agents

Receptor:

Route: SPAG

Term
Tobramycin
Definition

Trade Name:  TOBI

Indication: CF, bacterial conjuctivitis, burn wound infection

Contraindication: diarrhea, respirastory depression

Side effects: dysphonia, hearing loss, dizziness

Dosage:

Category: anti-infective agent

Receptor:

Route: SVN

Term
Zanamivir
Definition

Trade Name:  Relenza

Indication: influenza infection

Contraindication: asthma, COPD, emphysmea

Side effects: dypsnea, abdominal pain, bronchospasms, fatigue, fever, nausea

Dosage: 5 mg

Category: anti-infective agent

Receptor:

Route: DPI

Term
N-Acetylcysteine (NAC)
Definition

Trade Name: Mucomyst

Indication: acetaminophen overdose, bronchitis, COPD, CF, atelectasis

Contraindication: acute bronchospasms, asthma, respiratory insufficiency

Side effects: dyspnea, bronchospasm, fever, nause, hypotension

Dosage: 10% or 20%

Category: mucolytics

Receptor:

Route: SVN

Term
Dornase alfa
Definition

Trade Name:  Pulmozyme

Indication: atelectasis, CF

Contraindication:

Side effects: cough, chest pain, dyspnea, fever, laryngitis, rhinitis

Dosage: 1mg/ml

Category: mucolytics

Receptor:

Route: SVN

Term
Beractant
Definition

Trade Name:  Survanta

Indication: acute respiratory distress syndrome (ARDS), neonatal respiratory distress syndrome  (RDS)

Contraindication: bradycardia

Side effects: apnea, bradycardia, hyperoxia, hypotension, infection

Dosage:

Category: surfactant agent

Receptor:

Route: direct tracheal installation

Term
Calfactant
Definition

Trade Name:  Infasurt

Indication: acute respiratory distress syndrome (ARDS), neonatal respiratory distress syndrome  (RDS)

Contraindication: bradcardia

Side effects: bradycardia, cyanosis, hypoxia, intracranial bleeding

Dosage:

Category: surfactant agent

Receptor:

Route: direct tracheal installation

Term
Poractant Alfa
Definition

Trade Name: Curosurf

Indication: acute respiratory distress syndrome (ARDS), neonatal respiratory distress syndrome  (RDS)

Contraindication: anemia, bradycard, hypoglycemia, hypotension, hypthermia

Side effects: apnea, bradycardia, hyperoxia, hypoxia

Dosage:

Category: surfactant agent

Receptor:

Route: direct tracheal installation

Term
Montelukast
Definition

Trade Name:  Singular

Indication: allergic rhinitis, asthma, bronchospasm prophylaxis

Contraindication: acute bronchospasm, hepatits, jaundice, corticosteroid withdrawal

Side effects: anxiety, abdominal pain, cough, nasal congestion, nausea

Dosage:

Category: Leukotriene receptor antagonists

Receptor:

Route: PO tablets

Term
Zafirlukast
Definition

Trade Name:  Accolate

Indication: allergic rhinitis, asthma, bronchospasm prophylaxis

Contraindication: hepatitis, jaundice, acute bronchospasm

Side effects: cough, abdominal pain, cough, dyspnea, nausea, weight loss

Dosage:

Category: Leukotriene receptor antagonists

Receptor:

Route: PO tablets

Term
Zileuton
Definition

Trade Name:  Zyflo

Indication: asthma

Contraindication: acute bronchospasm, fever, infection

Side effects: anxiety, fatigue, tremor

Dosage:

Category: 5-LO inhibitor

Receptor:

Route: PO tablets

Term
Omalizumab
Definition

Trade Name: Xolair

Indication: allergic rhinitis, asthma

Contraindication: acute bronchospasm, respiratory insufficiency

Side effects: abdominal pain, cough, dyspnea, fatigue, nausea, pulmonary hypertension

Dosage: 150 mg

Category: Immunomodulators

Receptor:

Route: SQ injections

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