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Dr. Block's Amino Acid Study Questions
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10
Biochemistry
Professional
09/17/2011

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Term
Which amino acids have aliphatic sidechains?
Definition
GLY, ALA, VAL, LEU, PRO, ILE
Term
Which of the amino acids have aromatic sidechains?
Definition
PHE, TYR, TRP
Term
Which of the amino acids are basic?
Definition
HYS, LYS, ARG (His lysp argavatessssss me.)
Term
Which of the amino acids are acidic?
Definition
ASP, GLU, GLN, ASN
Term
Defects in the metabolism of which amino acids lead to maple syrup urine disease?
Definition
VAL, LEU, ILE
Term
What disorders arise from defects in the metabolism of tyrosine? Phenylalanine?
Definition
TYR - tyronosis, albinism, alcaptonuria
PHE - Phenylketonuria (retardation, early death)
Term
With respect to amino acids we discussed, what is the cause of pellegra?
Definition
deficiency of TRP in the diet. Causes diarrhea, dermatitis, dementia.
Term
Which amino acids have hydroxyl group sidechains? Contain sulfur? When in proteins, what kinds of reactions occur?
Definition
hydroxyl - SER, THR. Undergo phosphorylation reactions in situ.
sulfur - CYS MET. CYS can do disulfide linkages.
Term
What are the essential amino acids?
Definition
(The angry PVT TIM HALL).
PHE, VAL, THR, TRP, ILE, MET, HIS, ARG (in children), LYS, LEU
Term
Name 4 compounds from which amino acids are the precursors.
Definition
Histamine (HIS), Serotonin (TRP), Hemes and purines (GLY, SER), Glucose (ALA), Thyroid Hormone (TYR), Pyrimidines (SER)
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