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This type of cell is seen in the posterior nerve root ganglion cells. |
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these are found retina and the vestibulo cochlear ganglion of the eight cranial nerve |
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This type of nerve cells will have a single axon and a number of dendrites and the dendrites repeatedly branch to form a network. These cells are seen in the cerebral cortex, in the cerebellar cortex and in the anterior horn cells of the spinal cord. |
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_____ neurons are present in the cerebral cortex, sub cortical regions, as well as in the anterior horn of the spinal cord. |
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_____nerve cells are present in the posterior horn of the spinal cord, Thalamus and in the sensory cortex of the brain. |
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Nissl granules get disintegrate when there is injury to the axon, and this is known as ____ |
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buffer the external environment with respect to their chemical environment. |
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ensheath the axons of the central nervous system. |
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separate the central nervous system from the cerebro-spinal fluid. |
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In myelinated nerve fibers the velocity of impulse transmission is faster because the process of depolarization occurs only at the nodes of Ranveir and therefore it appears as if the impulses are jumping from one node to successive node. This type of impulse transmission is known as what type of conduction |
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Based on the diameter and velocity of impulse transmission the nerve fibers are also classified in to A, B and C types. And A is further divided in to A alpha, A beta A gamma and A delta fibers. This classification is known as what type of classification? |
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Somatic motor, proprioception |
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what fiber is Preganglionic autonomic |
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what dorsal root does pain and temperature |
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what type of fiber is Postganglionic sympathetic. |
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Name from Max to min. the relative susceptibility of the various fibers for anesthesia? |
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Name from Max to min. the relative susceptibility of the various fibers for Pressure |
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Name from Max to min. the relative susceptibility of the various fibers for hypoxia |
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Properties of nerve fibers: Excitability is the most important property of a nerve fiber. They are highly excitable when compared to any other tissues. They have the least ___ |
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70 to 120 meters per second. |
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The maximum velocity of impulse transmission in a myelinated nerve fiber in human being is about? |
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In a sensory nerve fiber, the impulses are transmitted from the periphery towards the center known as |
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If the transmission is in the opposite direction that is from the center towards the periphery in a sensory fiber it is known as |
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is potential change of variable amplitude and duration, which can’t get conducted over long distance and time. |
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For every ___ Na+ that are pumped out back into the ECF, ___ K+ will be brought back into ICF. |
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These two factors determine what 1. Difference in ion concentration across the membrane. 2. Difference in the membrane permeability for the ion. |
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monophasic action potential |
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To record _____ _____ ____, one of the recording electrodes should be in ECF and the other in ICF. |
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Biphasic action potential |
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For ______ ______ ______ recording, both the recording electrodes can be placed either in ECF or ICF. |
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Is physiological paralysis wherein the conduction of impulses in the intact nerve fibers will be lost temporarily. It may be due to stretch / distortion without any rupture. There is no physical damage to the nerve fibers and hence there will not be any degenerative changes. The recovery will be complete in this type of nerve injury. |
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Is intrathecal rupture of nerve fibers with an intact sheath. Degenerative changes occur in the nerve fibers and recovery is from such injury will be complete. |
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In this type there will be partial or complete damage to both the sheath and nerve fibers. Following this type of an injury, only about 80% of the functional recovery is observed. |
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The gap between the cut ends of the fiber should not be more than _____. If so regeneration will not occur. To facilitate regeneration, if the gap is more, _______ is done to minimize the gap to facilitate regeneration. |
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Is the duration after an effective stimulus, when a 2nd stimulus is applied, there will be no response for the 2nd stimulus. |
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sole foot region or axon telodendria or terminal boutons |
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As the motor nerve approaches this junction, it loses the myelin sheath and the bare nerve expands. This expansion is known as the |
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Pre-junctional blockers: Botulinum toxin (from Claustridium botulinum) prevents the synthesis and release of ____ |
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competitive inhibitor- They bind to the receptors available on the post-junctional membrane. Hence these receptors will not be available for ACh to bind when ACh gets liberated from the pre-junctional regions. Because of this there will not be opening of ligand gated sodium channels and hence no development of end plate potential. Consequently muscle action potential can’t get developed. |
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This also binds to the ACh receptors present on the post-junctional membrane and brings about the depolarization of the post-junctional membrane much like ACh. However, since the metabolism of this substance can’t be brought about by choline esterase, there will be a persistent end plate potential at the postjunctional membrane. Because of this the postjunctional membrane can’t get stimulated again. |
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Neostigmine, Physostigmine, Nerve gas (di isopropyl fluro phosphate |
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all these substances antagonize / inactivate the enzyme choline esterase. Hence ACh can’t get metabolized. This will also bring about the 21 persistent depolarization of the post junctional membrane. And hence block the transmission. |
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It is an autoimmune disease. • Antibodies are produced against the ACh receptors present on the postjunctional membrane. • So the receptors get destroyed. • ACh liberated during neuromuscular transmission fails to find adequate number of receptors for its action. • The generation of end plate potential is minimized. • This leads to no development of action potential in the muscle. • Features are easy fatigability, weakness. • If the condition is severe it can lead to respiratory paralysis and death. |
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supply the skeletal muscle fibers. They take their origin from the anterior horn cells or the corresponding cranial nerve motor neurons. Any time the motor fibers are damaged the muscle fibers under go paralysis. |
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an anterior horn cell or corresponding cranial nerve motor neuron with its axon and the number of muscle fibers supplied by it |
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quantal summation or multi fiber summation. |
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Increasing the number of motor units coming in to play can alter the tension developed in a muscle and this can be done by increasing the strength of the stimulus. The type of summation, which is produced this way, is known as |
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is composed of actin proteins. In addition to this, in this band there will be presence of troponin and tropomyosin proteins. |
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The ______ _____ namely the sarcolemmal membrane covers the muscle fiber. This membrane shows dipping in at specific parts that is at the junction of bands A & I. |
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The function of the _ _____ is to conduct the impulse through the muscle fiber |
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store and release of calcium ions during the process of contraction; expanded ends as the lateral cisterns. They closely surround the myofibrils. These form the sarcoplasmic reticulum. The expanded portion (terminal cistern) stores ionic calcium, which plays important role in excitation contraction coupling of muscle |
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the length of the muscle fiber decreases but the tension in the muscle fiber remains the same. |
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In this type of muscle the propagation of action potential is from cell to cell. That is the whole of the muscle acts as a single unit (structural syncitium). • It shows spontaneous development of action potential. • Present in the walls of GI tract, uterus, urinary bladder |
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Each fiber is almost similar to the skeletal muscle fiber but there are no definite cross striations. • There is no cell to cell propagation of impulse just like what is seen in skeletal muscle fiber. • There is no spontaneous activity in the muscle fiber. • Present in iris, and other examples are ciliaris muscle, erector pilorum muscle etc. |
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