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Dr Mo's drugs MOA & Indications
for Final
58
Pharmacology
Professional
05/08/2011

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Term
MOA of Zyflo?
Definition
5-lipoxygenase inhibitor; inhibits leukotriene formation
Term
Indications of Roferon A?
Definition
AIDS related Kaposi’s sarcoma, hairy cell leukemia
Term
Indications of Xolair?
Definition
Allergic asthma
Term
MOA of Motrin?
Definition
Antiplatelet effect, vasodilator, non-selective COX inhibitor
Term
Indications of Herceptin?
Definition
Breast cancer
Term
Indications of Selzentry?
Definition
CCR5 tropic HIV-1 infection
Term
Indications of CytoGam?
Definition
CMV reduction in kidney transplants
Term
Indications of Pegasys?
Definition
Chronic Hepatitis B, C
Term
Indications of Actimune?
Definition
Chronic granulomatous disease
Term
Indications of Digibind/DigiFab?
Definition
Digoxin overdose
Term
Indications of Intron A?
Definition
Genital warts, Hep B, C
Term
MOA of Medrol?
Definition
Glucocorticoid/corticosteroid Inhibit leukocyte infiltration @ site of inflammation, interfere with mediators of inflammation, response and suppress humoral immune response
Term
MOA of Periactin?
Definition
H1 antagonist
Term
Indications of Avonex?
Definition
Hep B and C, genital warts
Term
Indications of Cyclophosphamide?
Definition
Hodgkin’s lymphoma, Burkitt’s lymphoma, CLL, CML, AML, ALL
Term
Indications of ReoPro?
Definition
Inhibit platelet aggregation in angioplasty
Term
MOA of Benadryl?
Definition
Inhibits H1
Term
MOA of Chlor-Trimeton?
Definition
Inhibits H1
Term
MOA of Phenergan?
Definition
Inhibits H1
Term
MOA of Atarax?
Definition
Inhibits H1
Term
MOA of Claritin?
Definition
Inhibits H1
Term
MOA of Trasylol?
Definition
Interferes with chemical mediators thrombin, plasmins and kallikrein. Broad spectrum protease inhibitor
Term
Indications of Elidel?
Definition
Mild to moderate atopic dermatitis
Term
Indications of Betaseron/Extavia?
Definition
Multiple Sclerosis, Hep B,C
Term
MOA of Lexipafant?
Definition
Platelet-activating factor receptor antagonist
Term
Indications of HyperHEP B, HBIG?
Definition
Prevention of Hep B
Term
Indications of Synagis?
Definition
Prevention of RSV(respiratory syncytial virus) in infants and children
Term
Indications of Prograf/Protopic?
Definition
Prevention of organ rejection during transplant; atopic dermatitis; GVHD
Term
Indications of Neoral?
Definition
Prevention of organ rejection in transplants
Term
Indications of Neumega?
Definition
Prevention of severe thrombocytopenia/chemotherapy for nonmyeloid malignancy
Term
MOA of Accolate?
Definition
Prophylaxis and chronic asthma
Term
Indications of Zenapax?
Definition
Prophylaxis of organ rejection in patients receiving renal transplants (in combination with cyclosporine and corticosteroids)
Term
Indications of Rapamycin?
Definition
Prophylaxis of organ rejection in patients receiving renal transplants; GVHD
Term
Indications of Stelara?
Definition
Psoriasis; IL-12 inhibitor
Term
Indications of Kineret?
Definition
RA
Term
Indications of Azasan/Imuran?
Definition
RA
Term
Indications of Humira?
Definition
RA, Crohn’s disease, psoriasis
Term
Indications of Remicade?
Definition
RA, Crohn’s disease, psoriasis
Term
Indications of Enbrel?
Definition
RA, JIA, AS, and psoriasis
Term
Indications of Simponi?
Definition
RA, psoriatic arthritis, ankylosing spondylitis
Term
Indications of RespiGam?
Definition
RSV disease prevention
Term
Indications of Alferon-N?
Definition
Refractory genital warts, HIV/AIDS, Chronic Hep C
Term
MOA of Paxil?
Definition
SSRI
Term
MOA of Zoloft?
Definition
SSRI
Term
MOA of Sansert?
Definition
SSRI Antagonist @ 5-HT-2B
Term
MOA of Celebrex?
Definition
Selective COX 2 inhibitor
Term
MOA of Vioxx?
Definition
Selective COX 2 inhibitor
Term
MOA of Bextra?
Definition
Selective COX 2 inhibitor
Term
MOA of Singulair?
Definition
Selective Leu receptor antagonist inhibits the cysteinyl leu receptor.
Term
Indications of Rheumatrex/Trexall?
Definition
Stomach cancer, breast cancer and leukemia
Term
MOA of Baycadron/Maxidex/Ozurdex?
Definition
Suppression of neutrophil migration, decrease inflammatory mediators
Term
MOA of Deltasone?
Definition
Synthetic corticosteroid Glucocorticoid receptor agonist
Term
Indications of Gammagard/Gamimune-N/Gammar-P?
Definition
Thrombocytopenia (ITP) immunodeficiency
Term
MOA of Ridogrel?
Definition
Thrombolysis enhancer
Term
MOA of Dazoxiban?
Definition
Thromboxane synthetase inhibitor
Term
MOA of Pirmagrel?
Definition
Thromboxane synthetase inhibitor
Term
Indications of Cosmegen?
Definition
Trmt of Wilms’ tumor, testicular cancer
Term
MOA of Aspirin?
Definition
inhibits production of thromboxane; anti-inflammatory and antirheumatic due to inhibition of syntheses and release of prostaglandins
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