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The Metric System is derived from what units? |
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The International System of Units (SI) - the official system for weights and measures as stated in the U. S. Pharmacopeia-National Formulary SI base unitsName | Symbol | Quantity |
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metre | m | length |
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kilogram | kg | mass |
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second | s | time |
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ampere | A | electric current |
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kelvin | K | thermodynamic temperature |
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candela | cd | luminous intensity |
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mole | mol | amount of substance |
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What is the Apothecary system of measurement? |
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The traditional system of pharmacy, largely of historical significance, but components of the system are occasionally found on prescriptions. |
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The Apothecary system bases its fluid measurements on what units? |
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Minims (♏) Fluidrachms (fʒ or [image])* Fluidounces (f℥ or ℥)* Pints (pt) Quarts (qt) * When it is obvious that a liquid will be measured, the f can be deleted. |
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The Apothecary system bases its weight measurements on what units? |
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Grains (gr) Scruples (℈) Drachms (ʒ) Ounces (℥) |
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What is the Avoirdupois system? |
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A common system of commerce, using ounces and pounds. This system and the metric system are both used in the U. S. in purchasing and selling goods. |
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What is the Common or Household system of measurement? |
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The system that a patient would use at home with household items, such as teaspoons, tablespoons, cups, ounces, and pounds. |
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Length conversion: 1 inch = ? cm |
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Volume conversion: 1 pint = ? mL = ? fluidounces |
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473* mL = 16 fluidounces * Rounding to 480 mL is OK |
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Volume conversion: 1 fluid ounce = ? mL |
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29.6* mL * Rounding to 30 mL is OK |
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Volume conversion: 1 fluid dram = ? mL = ? teaspoonfuls |
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5 mL (considered 1 teaspoonful) |
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Volume conversion: 1 Tablespoonful = ? mL |
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Volume conversion: 2 cups = ? pint = ? mL |
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Volume conversion: 8 pints = ? gallon(s) |
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Weight Conversion: 1 kg = ? lb |
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Weight Conversion: 1 oz. = ? g |
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Weight Conversion: 1 grain = ? mg |
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What is the meaning of "w/v"? |
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Percent weight-in-volume The number of g of substance in 100 mL of solution or other liquid preparation. |
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What is the meaning of "v/v"? |
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Percent volume-in-volume. The number of mL of a substance in 100 mL of solution or other liquid preparation. |
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What is the meaning of "w/w"? |
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Percent weight-in-weight. The number of g of a substance in 100 g of preparation. |
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What is the meaning of "mg %"? |
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The number of mg in 100 mL or 100 g of the preparation. |
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What is the specific gravity of Ethanol? |
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What is the specific gravity of Water? |
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What is the specific gravity of Propylene Glycol? |
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What is the specific gravity of Glycerin? |
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Ratio Strength of 1:10,000 What does this mean for a solid in a liquid? |
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1 g solute/constituent in 10,000 mL of solution or liquid preparation |
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Ratio Strength of 1:10,000 What does this mean for a liquid in a liquid? |
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1 mL of constituent in 10,000 mL of solution or liquid preparation |
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Ratio Strength of 1:10,000 What does this mean for a solid in a solid? |
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1 g of constituent in 10,000 g of mixture |
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What is a solubility ratio? |
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The maximum amount of solute that can be dissolved in a given amount of solvent. Usually given as a range of solvent volumes (mL)needed to dissolve 1 part (g) of drug. |
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A term used to quantify a product in terms of its potency. It is a function of its activity compared to the activity of reference standard as determined in a bioassay. For USP grade products, the reference standard is outlined in the USP (which generally conform to international standards, i. e., I. U.) |
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Mass per unit volume Usually expressed as g/cc or g/mL |
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What is specific gravity? |
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The ratio of the weight of a substance to the weight of and equal volume of substance chosen as a standard (measured under controlled conditions). |
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Number of osmotically active molecules |
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What are moles and millimoles, in terms of weight? |
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Mole = molecular weight of a substance in grams Millimole = molecular weight of a substance in milligrams |
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Blood serum and tears contain the physiological equivalent of how many mOsm/L? |
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Among what types of products is tonicity a significant concern? |
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parenterals, opthalmics, and intranasal products |
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If a solution is hypertonic, what can it lead to? |
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For nonelectrolytes, such as dextrose, 1 mmol = ? mOsmol? |
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For electrolytes, the number of osmotically active particles in solution depend on the degree of dissociation, so: 1 mmol of NaCl = ? mOsmol? 1 mmol of CaCl2 = ? mOsmol? |
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NaCl = 2 mOsmol CaCl2 = 3 mOsmol |
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The osmolarity of a solution is mOsmol per ? |
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When the osmotic nature of a solution is reported as osmolality, it is in units of mOsmol per ? |
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For dilute solutions, are values of osmolarity and osmolality nearly the same? |
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Yes. As solutions become more concentrated, deviations from ideality occur and the values begin to diverge. |
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What do E-values express? |
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As sodium chloride equivalents, they express the amount of NaCl equivalent in osmolarity to 1 gram of a drug. The values consider contributions of the drug's MW, the number of solute particles produced, and the degree of dissociation of the particles. |
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What is a balance's sensitivity? |
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The smallest weight that will cause a perceptible movement of the balance, shown by the balance's indicator scale. |
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What is the sensitivity requirement (or maximum potential error)? |
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A measure of a balance's sensitivity and is defined in the USP as "the maximum change in load that will cause a specified change, one subdivision on the index plate, in the position of rest of the indicating element or elements of the balance" |
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Approximate concentrations of electrolytes in plasma: Cation mEq/L Na+ ? K+ ? Ca2+ ? Mg2+ ? |
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Cation mEq/L Na+ 140 K+ 4 Ca2+ 5 Mg2+ 2 |
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Approximate concentrations of electrolytes in plasma: Anion mEq/L Cl- ? HCO3- ? Protein- ? HPO42-, HPO4- ? SO42- ? Organic acids ? |
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Anion mEq/L Cl- 102 HCO3- 26 Protein- 16 HPO42-, HPO4- 2 SO42- 1 Organic acids 4 |
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What is the maximum allowable weighing error for prescription compounding? |
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5% Once the SR is known, one can calculate the minimum weighable quantity (MWQ) for a given prescription balance with a maximum of 5% error. Ex.: 6mg SR/5% error * 100% = 120 mg MWQ Below 120 mg, do an aliquot. |
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What are the two most common approaches to calculating drug doses? |
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Body weight and Body surface area |
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For IV drips, what are some classifications (rates) for macrodrips? |
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10 drops/cc 12 drops/cc 15 drops/cc |
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For IV drips, what is the drip rate for a microdrip? |
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For an electronic infusion pump (IV) what is the typical range of delivery? |
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How can rates of delivery of IV fluid be prescribed? |
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mL/hr mL/min drops/min mg/min or as total time of administration of the fluid |
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