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DNA and Heredity
Biology
35
Biology
12th Grade
10/25/2012

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Term
Initial work by Griffith and then McLead and McArty showed that DNA was responsible for
Definition
the "code" within the genes
Term

DNA is comprised of repeating monomers/subunits called

 

Definition
Nucleotides
Term
Each nucleotide is made of 3 parts:
Definition

5 Carbon sugar ribose

Phosphorous group

1 of 4 possible Nitrogen bases

Thymine, Cytosine, Guanine, Adenine

Term
Which nitrogen base have "double ring"?
Definition
Adenine and Guanine
Term
Which nitrogen base has "single ring" base?
Definition
Cytosine and Thymine
Term
Why is it important A can't go with C?
Definition
Three hydrogen bonds hold guanine to cytosine; two hydrogen bonds hold adenine to thymine.
Term
What's Chargaff Rule?
Definition
The amount of thymine will always be equal to the amount of adenine. As well Cytosine always equal with Guanine.
Term
Who discovery the double helix shape of the DNA was key to holding the "code of life."
Definition

James Watson

Francis Crick

Rosline Frankin

Term
Replication always proceeds by adding new bases to which of the ends?
Definition
3'
Term
The sites A, P, and E progressively occupied amino acids being assembled into a chain of polypeptides. These sites are part of:
Definition
large ribosomal subunit
Term
The process of transferring a gene's instructions for making a protein to an RNA molecule
Definition
Transcription
Term
During protein synthesis, the amino acid sequence is determined by the
Definition
Genetic code in the DNA molecule
Term
 A DNA sequence is changed from TATAGAAAT to ATTAGAAAT. What type of mutation has occurred?
Definition
inversion mutation
Term
If a mutation occurs in a somatic cell, how is it transmitted?
Definition
To all descendants of that cell
Term
What statement would be true if the strands that make up DNA are antiparallel?
Definition
The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand.
Term
Insertions or deletions are two kinds of mutations. Which statement is correct?
Definition
They result in a change in the reading frame, creating new groups of three letter codons
Term
DNA transcription takes place in the cell's?
Definition
Nucleus
Term
The sugars and phosphates in the "backbone" of a DNA strand are held together by ____.
Definition
Convalent bonds
Term
The two strands of a DNA double helix are held together by ________.
Definition
Hydrogen bonds between bases on opposite DNA strands
Term
Human chromosomes range in size dramatically, with the smallest (chomosome Y) being many times smaller than the largest (chromosome 1). What is responsible for determining the size of a chromosome?
Definition
The lenght of the DNA molecule in it.
Term
How can a cell, killed by heat in order to render it harmless, somehow still act to transform a second strain of bacterium from a noninfectious form into a disease carrier ex. pathogen?
Definition
The second(noninfectious) strain of bacterium was changed into a disease carrier (i.e, pathogen) by something from the heat-killed cell.
Term
To what does the phrase "ladder-like appearance" refer when considering the structure of DNA?
Definition
The complementary base pairs as rungs and the sugar-phosphate backbone as the rails.
Term
Would result from the actions of DNA polymerase during DNA replication? 
Definition
Two DNA polymerase molecules act to synthesize daughter DNA strands: one via a long continuous strand that moves in the same direction as the helicase, and a second polymerase synthesizes short segments of DNA that must be joined by ligase.
Term
What is the name Watson and Crick gave to the physical structure of DNA?
Definition
Double helix
Term
Rosalind Franklin and Maurice Wilkins used _________ to help discover the physical structure of DNA.
Definition
X-ray diffraction
Term
As a DNA strand is duplicated, the newly created strand is called ______ to the original strand.
Definition
Complementary
Term
Under normal circumstances, adenine will only be paired with ________ during DNA replication.
Definition
Thymine
Term
Chromosomes are made of which of the following molecules?
Definition
Protein, DNA
Term
In Griffith's experiments, heating the S_strain bacteria killed them, but did not completely destroy their __________.
Definition
DNA
Term
It is not the number ofdifferent nucleotides, but their _____________ that is important in the ability of DNA to code for all the variability of organisms.
Definition
Sequence  or Order
Term
The process by which a parent cell that is going to divide synthesizes an exact copy of its DNA is known as_________.
Definition
DNA replication
Term
What is the approximate error rate for DNA polymerase?
Definition
One error for every 10,000 bases added
Term
Which of the following can be caused by ultraviolet radiation in sunlight?
Definition
Adjacent thymines become linked together.
Term
DNA helicase
Definition
Cleaves hydrogen bonds that join the two strands of DNA
Term
DNA polymerase
Definition
Adds appropriate nucleotides to a newly forming DNA strand
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