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diuretic
as
10
Pharmacology
Graduate
11/02/2010

Additional Pharmacology Flashcards

 


 

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Term
hb
Definition
ghv
Term
mannitol
Definition

diuretic

 

osmotic diuretic

 

not reabsorbed in renal tubules

 

SFx: Extracellular volume expansion

hyperkalemia, hypernatremia

 

IV only

Diuresis without naturesis

Term
Acetazolamide
Definition

Diuretic

 

Carbonic Anhydrase Inhibitor

 

reduces the reabsorption of bicarbonate ions in proximal tubule

 

SFx: hyperchloremic metabolic acidosis, kidney stones, sulfa drug

 

needs 90% inhibition, treats mountain sickness

Term
Dorzolamide
Definition

Diuretic

 

Carbonic Anhydrase Inhibitor

 

reduces the reabsorption of bicarbonate ions in proximal tubule

 

SFx: hyperchloremic metabolic acidosis, kidney stones, sulfa drug

 

needs 90% inhibition, treats mountain sickness

Term
Brinzolamide
Definition

Diuretic

 

Carbonic Anhydrase Inhibitor

 

reduces the reabsorption of bicarbonate ions in proximal tubule

 

SFx: hyperchloremic metabolic acidosis, kidney stones, sulfa drug

 

needs 90% inhibition, treats mountain sickness

Term
Nesertide
Definition

diuretic

 

Brain natriuretic peptide

 

iv constant infusion,

Term
Desmopressin
Definition

anti diuretic

 

vasopressin agonist

 

increases permeability of distal convoluted tubule, inserts water channel

 

3000x affinity, long half-life

Term
Lypressin
Definition

anti diuretic


vasopressin agonist


increases permeability of distal convoluted tubule, inserts water channel


short half-life

Term
Conivaptan
Definition

diuretic

 

vasopressin antagonist

 

mixed v1 and v2 inhibitor

 

acute treatment of of CHS w/ hyponatremia

Term
Tovaptan
Definition

diuretic

 

vasopressin antagonist

 

mixed v1 and v2 inhibitor

 

acute treatment of of CHS w/ hyponatremia

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