Term
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Definition
Proximal Tubule Carbonic Anhydrase Inhibitor
Prevents resorbtion Na/HCO3 but renal compensation reduces effect
TX = Glaucoma, Epilepsy, Altitude sickness
Interacts with amphetamines by increasing urine pH
Can Cause metabolic acidosis
Can have allergic rxn similar to sulfide and deplete bone marrow |
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Term
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Definition
Loop diuretic in thick ascending limb inhibits Na/k/Cl cotransport and has a slight decrease on mg/ca2+
profound diuretcs, can cause
Hyponatremia, hypokalemia
hyperuremia, hyperglycemia
Tx hypercalcemia also
OTOXIC and hypersensivity due to similarity to sulfonimides |
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Term
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Definition
Chlorthiadone t1/2> hydrochlorthiazide
# 1 drug hypertension
Ceiling diuretics that block Na/Cl symporters.
Can cause HYPERCALCEMIA, hypokalemia, hyponatremia, hyperuremia, hyperglycemia
NSAIDS BLUNT
hypersensitivity reactions |
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Term
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Definition
| K sparing diuretic via Na channel blocker |
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Term
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Definition
aldosterone receptor antagonists
cause gynocomastia,decrease libido, mess with menstratioin, cause impotense, increase hairgrowth
collecting duct |
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Term
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Definition
Osmotic Diuretic used to maintain patency of renal arteries
avoid in patients with heart problems because increases intravascular volume load. |
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Term
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Definition
K sparing diuretic via Na channel blocker
toxicity = hyperkalemia |
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Term
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Definition
aldosterone receptor antagonists
ause gynocomastia,decrease libido, mess with menstratioin, cause impotense, increase hairgrowth
HYPERKALEMIA |
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Term
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Definition
Chlorthiadone t1/2> hydrochlorthiazide
# 1 drug hypertension
Ceiling diuretics that block Na/Cl symporters.
Can cause HYPERCALCEMIA, hypokalemia, hyponatremia, hyperuremia, hyperglycemia hypo magnisia
NSAIDS BLUNT
hypersensitivity reactions, increases lithium concentration
works at DCT |
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