Term
| Reticular Activating System components |
|
Definition
Locus Ceruleus (NE)
Raphe Nucleus (5-HT)
Reticular Formation |
|
|
Term
|
Definition
NE
Dopamine
5-HT
ACh
GABA |
|
|
Term
NE
what it does?
where its made? |
|
Definition
INC anxiety
Dec Depression
Locus Ceruleus |
|
|
Term
| Neuroectoderm derivatives: |
|
Definition
Neurons
Ependymal cells
Oligodendrocytes
Neural Crest cells |
|
|
Term
|
Definition
|
|
Term
NE
Increased levels cause:
Decreased levels cause: |
|
Definition
Inc NE: Anxiety & Mania
Dec NE: Depression |
|
|
Term
| What disease is assoc with degeneration of Basal Nucleus of Meynert & Dec ACh: |
|
Definition
|
|
Term
Nervous sys cell histo:
looks like Fried Egg |
|
Definition
|
|
Term
Nervous system cell
Forms multinucleated giant cells in CNS when infected with HIV |
|
Definition
|
|
Term
Nervous sys cell
Myelinates multiple CNS axons |
|
Definition
|
|
Term
Nervous sys cell
Myelinates one PNS axon |
|
Definition
|
|
Term
Nervous sys cell
damaged in Guillain Barre syndrome |
|
Definition
|
|
Term
Nervous sys cell
Damaged in multple sclerosis |
|
Definition
|
|
Term
Nervous sys cell
Macrophages of CNS |
|
Definition
|
|
Term
Nervous Sys cell
cells of blood brain barrier |
|
Definition
|
|
Term
Reticular Activating System
contents:
What happens if lesioned? |
|
Definition
Locus Ceruleus
Raphe nucleus
Reticular formation
if lesioned: COMA |
|
|
Term
Diuretic that is given
in order to LOWer Intracranial pressure |
|
Definition
Mannitol
give this when cerebral edema and you want to temporarily Dec ICP |
|
|
Term
|
Definition
Inc NE
Dec GABA
Dec Serotonin |
|
|
Term
|
Definition
Dec NE
Dec Serotonin
Dec Dopamine |
|
|
Term
Alzheimer Disease
NT change |
|
Definition
|
|
Term
Huntington Disease
NT change |
|
Definition
Inc Dopamine
Dec GABA
Dec ACh
|
|
|
Term
|
Definition
|
|
Term
Parkinson Disease
NT change |
|
Definition
Inc ACh
Inc Serotonin
Dec Dopamine |
|
|
Term
|
Definition
Facilitate GABAa action
by Inc FREQ of Cl channel opening |
|
|
Term
Hypothalamus
Paraventricular nucleus |
|
Definition
|
|
Term
Hypothalamus
Supraoptic nucleus |
|
Definition
|
|
Term
Hypothalamus
Anterior nucleus |
|
Definition
Cooling off (A/C)
Parasympathetics |
|
|
Term
Hypothalamus
Pre-Optic Nucleus |
|
Definition
|
|
Term
Hypothalamus
Suprachiasmatic nucleus |
|
Definition
|
|
Term
Hypothalamus
Dorsomedial nucleus |
|
Definition
GI
when stimulated:
savage behavior
obesity |
|
|
Term
Hypothalamus
Posterior nucleus |
|
Definition
Heating up body
Sympathetics |
|
|
Term
Hypothalamus
Lateral nucleus |
|
Definition
|
|
Term
Hypothalamus
Mammillary bodies |
|
Definition
| if lesioned: Wernicke-encephalopathy |
|
|
Term
Hypothalamus
Ventromedial nucleus |
|
Definition
|
|
Term
Hypothalmus
Arcuate nucleus |
|
Definition
Releasing hormones that affect
Anterior Pituitary |
|
|
Term
| 3 AA found in nuclear localization signals |
|
Definition
Proline
Lysine
Arginine
These AA are positive charged
so they are attracted to
neg charged DNA |
|
|
Term
Sleep Stage & EEG
Awake- eyes open -
Awake- eyes closed -
Stage 1-
Stage 2-
Stage 3-
REM |
|
Definition
Awake- eyes open - Beta wave (low amplitude)
Awake - eyes closed - Alpha wave
Stage 1 - Theta wave
Stage 2 - Sleep spindles & K complexes
Stage 3 - Delta wave (low freq)
REM - Beta wave
Stage 2 - bruxism
Stage 3 - Sleepwalking, Bed wetting (tx: Imipramine), night terrors
REM - dreaming; reduced by alcohol, benzos & barbituates |
|
|
Term
|
Definition
Melatonin
Valerian
Anti-histamines
Trazodone
TCAs (amitriptyline, doxepin)
Long acting Benzos (lorazepam, temazepam)
Zolpidem or Zaleplon
Eszopiclone
Ramelteon |
|
|
Term
Narcolepsy
first line tx
non pharm tx: |
|
Definition
First line: Modafinil
(stimulant)
non pharm tx:
avoid drugs that cause sleepiness
scheduled naps
|
|
|
Term
| tx: Narcolepsy with cataplexy |
|
Definition
Venlafaxine
Fluoxetine
Atomoxetine |
|
|
Term
| Brain structure responsible for extraocular movement during REM |
|
Definition
PPRF
Paramedian Pontine Reticular Formation |
|
|
Term
| What cell types are derived from Neural Crest cells: |
|
Definition
| ANS, Celiac Ganglia, Chromaffin Cells (adrenal medulla), Dorsal Root Ganglia, Odontoblast, Cranial nerves, Schwann cells, Pia & Arachnoid mater, Skull bones, Melanocytes, Aortico-pulmonary septum, Parafollicular (C cells) of Thyroid, Thyroid & Laryngeal cartilage |
|
|
Term
|
Definition
determines SKELETAL development
Retinoic Acid alters its expression (teratogenic) |
|
|
Term
|
Definition
| made in adipocytes; Large fat cells makes MORE leptin than small fat cells. Leptin dec Food intake; the more leptin you have the less food you want to eat; if you have no leptin --> you will be FAT |
|
|
Term
|
Definition
Eye looks "Down and Out"
Ptosis, Pupillary dillation, loss of accommodation |
|
|
Term
|
Definition
eye drifts UP & IN (medial) -> Vertical diplopia
problems when reading newspaper or walking downstairs |
|
|
Term
|
Definition
| Medially directed eye= ADDuction |
|
|
Term
| Medial Longitudinal Fasiculus |
|
Definition
Internuclear opthalmoplegia
Impaired horizontal eye movement & weak adduction of affected eye of affected eye
ABDuction nystagmus of contralateral eye |
|
|
Term
|
Definition
Kayser-Fleischer Ring
Chronic hepatitis --> Copper is pro-oxidant and causes damage to hepatic tissue by generating free radicals. Eventually the copper leaks our of hepatocytes --> circulation and is deposited into tissues, cornea, basal ganglia.
Cause Basal Ganglia Atrophy. |
|
|
