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Disorders of Fluid & Electrolytes
Test 2.
26
Pathology
Undergraduate 1
02/11/2013

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Cards

Term
Where is most fluid found?
Definition
Intracellular space- 40%
Term
What does osmosis want?
Definition
Even distibution... moves from side that has fwer non-diffusible partivles to the side that has more.... It wants to dilute the side it is moving to
Term
3 Tonicity Solutions
Definition
  1. Isotonic- happy cell
  2. Hypotonic solution- few particles on outside more h20 in circle= cell takes on water given for dehydration.
  3. Hypertonic solution-  more particles on outside pulls h20 out of cells, cell shrink
Term
What is hydrostatic  pressure
Definition
Pressure that fluids excerts on cell wall
Term
What is Colloid Osmotic Pressure?
Definition
particles pull fluid to try and dilute selfs evenly
Term
What is Lymph Drainage all about?
Definition
excess fluid & particles are pulled away by lymph. Allow cells and tissues to be more even.
Term
What maintains H20 Balance, and what are 2 things it looks at?
Definition
Hypothalmus- Serum osmolality, Blood volume
Term

How does Hypothalmus work?

(SERUM OSMOLARITY)

Definition
  1. Tells Thirsty- makes ur drink
  2. Secrete ADH- holds water-stops peeing
  3. This increases Extracellular water volume
Term

 H20 balance depends on what 2 things?

 

Definition
  1. Blood volume
  2. quality/ tonicity of blood
Term

1.What happens when you have high Osmolity (increased particles?)

2. LOW Osmolatity

Definition

1. High

  • Thirsty
  • ADH released

2. Low

  • Lack thirst
  • Decrease ADH relase

 

Term

Diabetes insipus- water down weak urine

Can be 2 ways? Caused by brain

-THIS PERSON HAS- excessive urine, Hypertonic dehyration(NA) What will this person look like?

Definition
  • Nurogenic- decreased ADH
  • Nephrogenic Decreased renal responce to ADH
  1. ADH- LOW
  2. URINE O- High
  3. B/V- Low
  4. B/P- Low
  5. NA- High
Term

SIADH- what causes

THIS PERSON HAS- decreased urine output, dilutional hyponatremia, what will this person look like?

Definition

Faliure of hypothalmus d/t transient....Excessive ADH secretion.

  1. URINE- low
  2. B/V- High
  3. B/P High
  4. NA- LOW
Term
Substances that dissociate in solutions to form charged particles or ions... These are essential in metabolic process
Definition
Electrolytes
Term

Why does "retaining sodium" cause high blood pressure?

IT IS MAJOR ELECTROLYTE

Definition
It pulls water from the intertial space in to the vascular space to try and water it down.
Term

You have a patient: Confused & hypernatremic

 

1. The doctor says that he is confused d/t the size of his brain cells. Why would this happen?

 

2. A medical student suggest giving him a hypotonic iv, why? no answer.

 

3. The docotor said that might worsen the change in his brain cell size, and that his blood osmolarity should be corrected slowly... why?

Definition

1. Shrunk.. d/t sodium in blood blood pulled the water out of his brain cells.

 

3. If this patient was given a hypotonic soulition it would blow the brain cells back up to fast, this needs to be done slowly.

Term

Neurons responced to hypertoncity... How does the body compinsate on own?

  1. What happens if cells turn back to isotonic state to fast?
  2. What kind of solution would we use to fix fluid problems?
Definition
  • Increase blood osmolarity cause cells to shink- they lose water to vasular space
  • Nerve cells produce intracellular osmoles to keep their osmolaity balanced with the blood.
  1. If to fast nerve cells will turn hypertonic and will cause brain cells to swell = cerebralle edema.
  2.  Need 1/2 normal saline and run= SLOW
Term
What is the Role of Potassium?
Definition
  • Control cell resting potential
  • Needed for NA/K pumo
  • Exchange for H to buffer changes in blood ph
Term

In Blood how does K+ Control resting potential- HYPERKALEMIA?

What organ are we going to worry about and why?

Definition
  • Hyperkalemia raises resting potential toward threshold- cell fires easier.
  • It increases ability for an action potential to occure.
  • Heart= Tachyrythmia

 

 

 

Term

In blood how does K+control restin potential- HYPOKALEMIA?

What organ do we worry about and why?

Definition
  • Low potassium in blood = low in tissue, It pulls resting potential away from threshold and makes it hard to fire.
  • Heart= Bradydisrythmias.
Term

What will happen to Blood k+ levels when the client has

 

  1. Hyperaldosteronism
  2. Loop Diuretics

 

 

Definition
  1. K+ will decrease
  2. Decrease

 

Term
Potassium acts as a buffer how does is control Alkalosis & Acidosis?
Definition
  1. Alkalosis- not enough H+ in blood- cells release H+ to fix imbalance and take up K+ ions in exchange- Blood k+ will decrease = hypokalemia
  2. Acidosis- Too many H+ ions in blood, cells keep H+ ions inside to fix imbalance and release K+ in exchange- Blood K+ increaeases= Hyperkalemia
Term

-Calcium- What does it do?

What does extracellular do?

What does intracellular do?

IT ALSO DOES CLOTTING

Definition

1. Block na+ gates in nerve & muscle cells to control excessive firing(tetany)

2. Needed for all muscle contractions (Cardiac, Skeletal)

Term
What increases serum Ca+ and what decreases?
Definition

Parathyroid Hormone- Increases

Calcitonin- Decreases

Term

Extracellular Ca+ controls nerve firing how?

 

  • Hypercalcemia
  • Hypocalcemia

Which causes Chyvostek sign?

Definition
  • Hypercalcemia- Blocks Na+ gates nerves less able to fire
  • Hypocalcemia- Blocks fewer na+ gates, nerves fire more easy.
  • HYPOCALEMIA
Term

What is the role of magnesium?

What serious problem can it cause?

Definition
  • Cofactor in enzyme reaction
  • Regulates CA+ leveles by binding to receptors
  • Interdependant with K+

***Cause life threatening heart arrythmias

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