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Diseases of the Skin
n/a
53
Microbiology
Undergraduate 2
05/01/2011

Additional Microbiology Flashcards

 


 

Cards

Term
Coagulase 
Definition
Enzyme that clots plasma 
Term
Lipase 
Definition
Enzyme that colonizes oily skin, breaks down fatty acids
Term
Nuclease 
Definition
Enzyme that braeks down DNA
Term
Staphylokinase 
Definition
Enzyme that digests blood clots 
Term
Hyaluronidase
Definition
Enzyme that attacks connective tissue 
Term
Deoxyribonucleases 
Definition
Enzyme that blocks neutrophil activity
Term
Proteases 
Definition
Enzymes that block neutrophil migration 
Term
M Protein 
Definition
Enzyme that inhibits phagocytosis 
Term
Hemolysin 
Definition
Enzyme that ruptures erythrocytes 
Term
Erythrogenic toxins 
Definition
Enzyme that causes a red rash and shedding of the skin. 
Term
Streptokinase 
Definition
Enzyme that dissolves blood clots. 
Term

Folliculitis, furuncluosis, carbuncles, sty

(cause)

Definition
Staphylococcus aureus 
Term

Scalded Skin Syndrome

(cause)

Definition
Staphylococcus aureus strains that produce exfoliation toxin 
Term

Impetigo

(cause)

Definition
Streptococcus pyogenes, Staphylococci, Gram + cocci in chains 
Term

Erysipelas

(cause)

Definition
Streptococcus pyogenes
Term

Necrotizing fasciitis

(cause)

Definition
Streptococcus pyogenes, Staphylococcus aureus 
Term

Pseudomonas infections 

(cause)

Definition
Pseudomonas causing superficial rashes, otitis externa, acne, and burns 
Term

Anaerobic abscesses

(cause)

Definition
Bacteriodes fragilis and other anaerobic Gram - non spore forming rods 
Term

Acne

(cause)

Definition
Proprionibacterium acnes 
Term

Gas Gangrene

(cause)

Definition

Clostridium perfringens

(anaerobic bacteria)

Term

Rubeola (measles)

(cause)

Definition
Rubeola Virus 
Term

Rubella

(cause)

Definition
Rubella Virus 
Term

Warts

(Cause)

Definition
Human Papilloma Viruses (HPV)
Term

Small Pox

(cause)

Definition
Variola Virus 
Term

Chicken Pox and Shingles

(cause)

Definition
Varicella-Zoster virus 
Term

Herpes Simplex Virus

(cause)

Definition
Herpes Simplex Virus Type 1 
Term

Cutaneous Mycoses

(cause)

Definition
Demotophyes: Trichophyton, Microsporum, Epidermophyton
Term

Candidasis

(cause)

Definition
Candida albicans 
Term

Neonatal Conjunctivitis Ophthalmia

(cause)

Definition
Neisseria gonorrhoeae, Chlamydia trachomatis
Term

Bacterial Conjunctivitis

(cause)

Definition
Streptococcus pyogenes, S. pneumonia, Staphylococcus aureus, Haemophilius influenzae 
Term

Trachoma

(cause)

Definition
Chlamydia trachomatis
Term

River Blindness (onchocerciasis)

(cause)

Definition
Transmitted by flies, parasite Onchocerca volvulus
Term

Scalded Skin Syndrome

(characteristics)

Definition

Exfoliation toxin causing desquamation 

Similar to systemic impetigo

Mainly affecting babies and newborns 

SSSS

Term

Impetigo

(characteristics)

Definition

From Staph


     Toddlers, school age, adults

     This walled vesicles that rupture and crust over

From Strep Pyognese

     Isolated pustulates which crust over

     Mostly in newborns

     Can be epidemic in hospital nurseries

Pustules, crust
Adults can get it

Most often caused by S. aureus

Term

Erysipelas

(characteristics)

Definition

Invasive

 

Enters through small wound or incision

 

Spreads to dermis and subcutaneous tissue

 

Often on face and extremities

Term

Necrotizing fasciitis

(characteristics)

Definition

Flesh eating bacteria

 

Small abrasions on cuts

 

very toxic strains which grow rapidly, produce invasive enzymes and toxins

Term

Pseudomonas infections

(characteristics)

Definition

Superficial rash (hot tubs)

 

Otitis externa

 

Burn patients

 

Cystic fibrosis lung infections (P. aeruginosa is the most common

 

lung infections in Cystic Fibrosis patients

Term

Measles

(characteristics)

Definition

Kopliks spots in mouth

Fever, cough, maulopapular rash

Vaccine available

Term

Acne

(characteristics)

Definition

Cystic acne

 

Process involves inflammatory response

 

Pores become blocked, bacteria use the sebum and break it down

 

into fatty acids

 

Lipase

 

Fatty acids situmlate the inflammatory response

Term

Gas Gangrene

(characteristics)

Definition

Anerobes: produce collagen and protein degrading enzymes that act

 

as virulence factors

 

Charcteristic Odor

 

Attacks areas of poor circulation

 

Clostridia ferment the sugars in the tissue and produce hydrogen

 

and carbon dioxide that swell tissue

 

Toxins kills tissue and may enter the blood stream to cause

 

systemic illness

 

Debridement and amputations are the most common treatments

 

Hyperbarric chamber to drive Oxygen to wounds

Term

Rubeola

(characteristics)

Definition

Kopliks spots in mouth

Fever, cough, maulopapular rash

Vaccine available

Infects 30 million children per year globally and kills 350k per year

Also known as Measles 

Term

Rubella

(characteristics) 

Definition

Very Contagious

 

Usually mild

 

Macular Rash

 

Possible fetal damage if mother infected during first trimester-35%

 

chance

 

Congenital rubella sydrome

Term

Warts; Papillomas

(characteristics)

Definition

Different virus types

 

Plantar warts - HPV-1

 

Flat warts- HPV 3, 10, 28, 49

Term

 

Small pox

(characteristics)

Definition

 

Elevated lesions filled with fluid

Eliminated due to worldwide vaccine (eradication)

Very infectious viral disease (epidemic)

Considered a bioterrorism agent 

Term

Chicken pox

Shingles

(characteristics)

Definition

Vaccine available for chicken pox 

 

Vaccine for shingles in people over 60 (does not cure if you have it)

 

Common

Benign

Life threatening for immunocompromised individuals

Recuperation can involve Varicella-zoster virus infection

Chx Pox can reemerge as shingles 

Term

Herpes simplex virus

(characteristics)

Definition

Cold sores, fever blisters

90% of people in the US are infected

Spread through oral route

 

Term

Cutaneous Mycoses

(characteristics)

Definition
Colonizes outer layer of epidermis
Term

Candidiasis

(characteristics)

Definition

Known as thrush

Immunocompromised individuals susceptible

Fungal infection 

 

Term

Neonatal conjunctivitis ophthalmia

(characteristics)

Definition
Occurs in babies less than 28 days old 
Term

Bacterial Conjunctivitis

(characteristics)

Definition

Known as pink eye

Can be both bacterial and viral

Causes redness and inflammation 

 

 

Term

Trachoma

(characteristics)

Definition

Bacterial infection 

Eyelashes grow into eyes, causing blindness

Common in Africa

Vaccine available 

 

Term

River Blindness (onchocerciasis)

(characteristics)

Definition

Chronic

Endemic

Black flies spread disease

Ivermecitin is drug; once a year

Found in S. America and Africa

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