Term
|
Definition
|
|
Term
Subacute bacterial endocarditis
|
|
Definition
α-hemolytiac streptococci (oral cavity)
enterococci, staphylococci
|
|
|
Term
Acute bacterial endocarditis
(cause)
|
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Borrelia burgdorferi, spirochete |
|
|
Term
|
Definition
|
|
Term
Endemic murine typhus
(cause)
|
|
Definition
|
|
Term
Infectious mononucleosis
(cause)
|
|
Definition
Epstein-Barr virus (Human herpes virus 4) |
|
|
Term
|
Definition
|
|
Term
Emerging viral hemorrhagic
fevers
(cause)
|
|
Definition
Marburg, Ebola, Lassa, Argentine and Bolivian fevers |
|
|
Term
|
Definition
|
|
Term
|
Definition
Plasmodium falciparum and other Plasmodium |
|
|
Term
|
Definition
Human immunodeficiency virus 1 or 2
|
|
|
Term
Puerperal sepsis
(characteristics)
|
|
Definition
Also known as childbirth fever
Semmelweis and Holmes proved that the spread was caused by hospital staff and tools |
|
|
Term
Subacute bacterial endocarditis
(characteristics)
|
|
Definition
People with heart conditions susceptible after dental work
Fever, weakness, heart murmur
If untreated, fatal within months
Treated with prophylitic antibiotics |
|
|
Term
Acute Bacterial Endocarditis
(characteristics) |
|
Definition
Bacteria "hear " and damage heart valves
fatal if untreated
|
|
|
Term
|
Definition
Black death, carried by rats and transmitted by rat fleas, buboes, pneumonic plague
Gram - rods living in lymph nodes
Killed 25% of Europe in the 1400s |
|
|
Term
Lyme Disease
(characteristics) |
|
Definition
Resevoir: Field Mouse
Tick feeds on mouse and becomes vector
Ticks may bite deer and humans
Three Stages:
1: bullseye rash and flu like symptoms
2: heart and neurological symptoms
3: arthritis
May become chronic |
|
|
Term
Epidemic Typhus
(characteristics) |
|
Definition
Carried by human body louse; epidemic in unsanitary conditions such as fox holes in WWI |
|
|
Term
Endemic Murine Typhus
(characteristics) |
|
Definition
Sporadic disease, carried by rats and squirrels, transmitted by rat fleas |
|
|
Term
Infectious Mononucleosis
(characteristics) |
|
Definition
Mainly affecting 15-25 year olds in US
Causes B cell proliferation and immune response
Also known as "kissing disease"
4-7 week incubation period
|
|
|
Term
Yellow Fever
(characteristics) |
|
Definition
Carried by mosquitoes
Name comes from jaundice
Endemic in Central and South America and Africa (formerly US endemic killing pioneers)
20% mortality if untreated
Walter Reed |
|
|
Term
Emerging Viral Hemorrhagic Fevers
(characteristics) |
|
Definition
High mortality rates
Typically causing severe hemmhorages |
|
|
Term
Toxoplasmosis
(characteristics) |
|
Definition
Congenital infections causing still births or birth defects
Definitive host: cat
Intermediate host: rodent
Caught from undercooked meat or cat feces |
|
|
Term
Malaria
(characteristics) |
|
Definition
2-4 million deaths per year
antibiotic resistant strains
formerly common in US, mosquito control has reduced incidence |
|
|
Term
|
Definition
Life cycle:
● Harm to T Cells
○ Death of T cells and other WBC results in leukopenia and loss of T4 memory cells
○ Giant T cells form - syncityia - which leads the way for virus invasion cell to cell
● Nervous system harmed
○ Infected macrophage cross the blood brain barrier and virus enters the nervous system
Incidence:
● Sub Saharan Africa is most common
● South and Southeast Asia is next
Detecting:
● ELISA - screening test
● Western Blot - confrims ELISA
○ Tissue cultrue cells are infected with virus if present
○ Tissure culture medium with contain virus particles
○ Virus particles are treated to release the proteins
○ Protiens seperated by gel electrophroesis
○ Detect proteins using antibodies to the proteins
Patterns of transmission:
● HIV-1: Most common in US, Western World, and Sub-saharan Africa
● HIV-2: Most common in Western Africa; develops slower
● Clades are subtypes of major groups
Treatment:
● US says to begin treatment if your CD4 count is between 350 and 500 or if you’ve developed an opportunistic infection
● Highly Avtive Anti-retroviral Therapy (HAART) is 10 years old
● NRTI’s and NNRTI’s are fustion/entry inhibitors and integrase inhibtors.
● Suggest 2 NRTI’s, an NRRTI, and PI (boosted with ritonavir)
|
|
|