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Diseases of the Cardiovascular and Lymphatic Systems
n/a
26
Microbiology
Undergraduate 2
05/01/2011

Additional Microbiology Flashcards

 


 

Cards

Term

Puerperal sepsis

(cause)

Definition

Streptococcus pyogenes

Term

Subacute bacterial endocarditis

Definition

α-hemolytiac streptococci (oral cavity)

enterococci, staphylococci

Term

Acute bacterial endocarditis

(cause)

Definition
Staphylococcus aureus
Term

Plague

(cause)

Definition
Yersinia pestis
Term

Lyme disease

(cause)

Definition

 

Borrelia burgdorferi, spirochete

Term

Epidemic typhus

(cause)

Definition
Rickettsia prowazekii
Term

Endemic murine typhus

(cause)

Definition
Rickettsia typhi 
Term

Infectious mononucleosis

(cause)

Definition

 

Epstein-Barr virus (Human herpes virus 4)

Term

Yellow fever

(cause)

Definition
Arbovirus
Term

Emerging viral hemorrhagic

 fevers

(cause)

Definition
Marburg, Ebola, Lassa, Argentine and Bolivian fevers
Term

 

Toxoplasmosis

(cause)

Definition
Toxoplasma gondii
Term

Malaria

(cause)

Definition
Plasmodium falciparum and other Plasmodium
Term

HIV

(cause)

Definition

Human immunodeficiency virus 1 or 2

Term

Puerperal sepsis

(characteristics)

Definition

Also known as childbirth fever 

Semmelweis and Holmes proved that the spread was caused by hospital staff and tools 

Term

Subacute bacterial endocarditis

(characteristics)

Definition

People with heart conditions susceptible after dental work

Fever, weakness, heart murmur

If untreated, fatal within months

Treated with prophylitic antibiotics 

Term

Acute Bacterial Endocarditis 

(characteristics)

Definition

Bacteria "hear " and damage heart valves

fatal if untreated 

 

Term

Plague

(characteristics)

Definition

Black death, carried by rats and transmitted by rat fleas, buboes, pneumonic plague

Gram - rods living in lymph nodes

Killed 25% of Europe in the 1400s

Term

Lyme Disease

(characteristics)

Definition

Resevoir: Field Mouse

Tick feeds on mouse and becomes vector

Ticks may bite deer and humans

 

Three Stages:

1: bullseye rash and flu like symptoms

2: heart and neurological symptoms

3: arthritis

 

May become chronic 

Term

Epidemic Typhus

(characteristics)

Definition
Carried by human body louse; epidemic in unsanitary conditions such as fox holes in WWI
Term

Endemic Murine Typhus

(characteristics)

Definition
Sporadic disease, carried by rats and squirrels, transmitted by rat fleas 
Term

Infectious Mononucleosis

(characteristics)

Definition

Mainly affecting 15-25 year olds in US

Causes B cell proliferation and immune response

Also known as "kissing disease"

4-7 week incubation period 

 

Term

Yellow Fever 

(characteristics)

Definition

Carried by mosquitoes

Name comes from jaundice

Endemic in Central and South America and Africa (formerly US endemic killing pioneers)

20% mortality if untreated 

Walter Reed 

Term

Emerging Viral Hemorrhagic Fevers

(characteristics)

Definition

High mortality rates

Typically causing severe hemmhorages 

Term

Toxoplasmosis

(characteristics)

Definition

Congenital infections causing still births or birth defects

Definitive host: cat

Intermediate host: rodent

Caught from undercooked meat or cat feces 

Term

Malaria

(characteristics)

Definition

2-4 million deaths per year

antibiotic resistant strains

formerly common in US, mosquito control has reduced incidence 

Term

HIV

(characteristics)

Definition

Life cycle:

      Harm to T Cells

      Death of T cells and other WBC results in leukopenia and loss of T4 memory cells

      Giant T cells form - syncityia - which leads the way for virus invasion cell to cell

      Nervous system harmed

      Infected macrophage cross the blood brain barrier and virus enters the nervous system

Incidence:

      Sub Saharan Africa is most common

      South and Southeast Asia is next

Detecting:

      ELISA - screening test

      Western Blot - confrims ELISA

      Tissue cultrue cells are infected with virus if present

      Tissure culture medium with contain virus particles

      Virus particles are treated to release the proteins

      Protiens seperated by gel electrophroesis

      Detect proteins using antibodies to the proteins

Patterns of transmission:

      HIV-1: Most common in US, Western World, and Sub-saharan Africa

      HIV-2: Most common in Western Africa; develops slower

      Clades are subtypes of major groups

Treatment:

      US says to begin treatment if your CD4 count is between 350 and 500 or if you’ve developed an opportunistic infection

      Highly Avtive Anti-retroviral Therapy (HAART) is 10 years old

      NRTI’s and NNRTI’s are fustion/entry inhibitors and integrase inhibtors.

      Suggest 2 NRTI’s, an NRRTI, and PI (boosted with ritonavir)

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