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Digestive System Part 2
starts at pharynx ends at sm intestine
81
Anatomy
Undergraduate 1
11/19/2012

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Term
The Pharynx (Throat)
•A common passageway for
Definition
solid food, liquids, and air
Term
Food passes through the _______ & _____ to the esophagus
Definition
oropharynx & laryngopharynx
Term
Wall of esophagus has what 3 layers
Definition

1.Mucosal

2.Submucosal

3.Muscularis externa

remember it doesnt have a serosa but does have an adventicia
Term
The Esophagus description including length & width
Definition
•A hollow muscular tube
•About 25 cm (10 in.) long and 2 cm (0.80 in.) wide
Term
esophagus fcn
Definition
Conveys solid food and liquids to the stomach
Term
esophagus begins ___________ & enters the abdominopelvic cavity through the _________
Definition
1. posterior to cricoid cartilage

2. the esophageal hiatus
Term
the esophagus Is innervated by
Definition
fibers from the esophageal plexus
Term
Mucosa of the esophagus contains:(2)
Definition
1.Nonkeratinized & stratified squamous epithelium

2•Simple columnar epithelium
Term
Mucosa and submucosa of the esophagus form:
Definition
Large folds that extend the length of the esophagus
Term
the muscularis mucosa of the esophagus concists of (1)
Definition
Irregular layer of smooth muscle
Term
muscularis mucosa fcn of the esophagus(2)
Definition
Contraction alters the shape of the lumen
and moves epithelial pleats & folds
Term
Submucosa of the esophagus contains (1)
Definition
esophageal glands
Term
esophageal glands fcn
Definition
Which produce mucous secretion
=Reduces friction between bolus and esophageal lining
Term
Muscularis externa of esophagus has (2):
Definition
inner circular
outer longitudinal muscular layers
Term
Swallowing is Also called
Definition
deglutination
Term
Swallowing Uses muscles known as
Definition
pharyngeal constrictors

(Can be initiated voluntarily
•Proceeds automatically)
Term
swallowing Is divided into 3 phases
Definition
1. Buccal phase
2. Pharyngeal phase
3. Esophageal phase
Term

major fcns of the stomach:

produces what important glycoprotein (1)

and give fcn (1)

Definition

 4.Produce intrinsic factor:

  required for absorption of vitamin B12 in small intestine

Term
•Short lesser curvature forms the _____ surface
•Long greater curvature forms the ____________ surface
Definition
medial surface
lateral surface
Term
Regions of the Stomach
_______________region of the stomach that connects to the esophagus
Definition
cardia
Term
Regions of the Stomach
_______________ superior to the junction b/n the stomach and the esophagus
Definition
fundus
Term
_______________ functions as a mixing chamber for food and secretions
Definition
body
Term
_______________ empties into the duodenum
Definition
pylorus
Term
when the stomach is relaxed the mucous is thrown into folds called________ & give fcn
Definition
rugae, allow stomach lumen to exapand
Term
name the stomach tissue layers that Contain extra layers of smooth muscle cells (2)
Definition
Muscularis mucosae & muscularis externa
Term
name the 3 layers of muscle in muscularis externa of stomach
Definition

1.Oblique layer   (inner)

2. circular layer

3.longitudinal layers (outer)

Term
name the epithelium lines all portions of stomach
Definition
simple columnar
Term
give the fcn of the stomach Epithelium
Definition
Epithelium is a secretory sheet

=Produces mucus that covers interior surface of stomach
Term
•______________________, shallow depressions that open onto the gastric glands
Definition
gastric pits

aka gastric pits house gastric glands
Term
fcn of the cells contained in the gastric pits & include what type of cell they are
Definition

Mucous cells in each gastric pit

 

fcn: actively divide, replacing superficial cells

Term
Gastric Glands are located in what stomach regions (2) and extend into what tissue layer

2•Each gastric pit communicates with several _________
Definition
1. fundus & body into lamina propia

2.gastric glands
Term

cells of the gastric gland (2)

together they secrete (1)

Definition
parietal & chief gastric juice
Term
parietal cells secrete (2)
Definition
secrete intrinsic factor and hydrochloric acid
Term
chief cells secrete
Definition
secrete pepsinogen
Term
pepsinogen def

how is activated
Definition
inactive proenzyme; most abundant near the base of the gastric gland

acid in stomach (becomes pepsin)
Term
•P/D1 cells fcn
Definition
produce ghrelin (stimulates hunger)
Term
pepsin fcn
Definition
digest proteins
Term

Regulation of Gastric Activity such as Production of acid and enzymes by the gastric mucosa can be :

controlled by (1)

regulated by (2)

Definition

1•Controlled by the CNS

 

2•Regulated by : short reflexes of ENS

hormones of digestive tract

Term
3 phases of gastric control
Definition
1. Cephalic phase
2. Gastric phase
3. Intestinal phase
Term

Pyloric Glands are located in the ______ of stomach

2. what kind of cells are located here (2)

name the most abundant

Definition

1.pylorus

2. mucous & enteroendocrine cells

 

most abundant pylorus cell: G cell

Term
which enteroendocrine cells produce gastrin
Definition
G-cells (most abundant cell in pylorus)
Term
fcn of gastrin
Definition
stimulates gastric secretion & contractions
Term
D cells release & fcn
Definition
somatostatin
=inhibits release of gastrin
Term
Digestion and Absorption in the Stomach

proteins are digested by
carbs
lipids
Definition
1.pepsin in stomach
2.salivary amylase
3. lingual lipase
Term
give 3 events that happen in stomach during digestion
Definition

1.Stomach contents Become more fluid 2•pH approaches 2.0

3•Pepsin activity increases

(Protein disassembly begins)

 

(Although digestion occurs in the stomach, nutrients are not absorbed there)

Term
The Small Intestine fcn
Definition
90% of nutrient absorption occurs in the small intestine
Term
3 parts of sm intestine in order
Definition
Duodenum (1 ft),
jejunum (6-8 ft),
ileum (8-12 ft)
Term
the duodenal glands aka
Definition
Brunner’s glands
Term
fcn of Brunner’s glands
Definition
produces mucous when chyme arrives from the stomach
Term
the duodenum of the sm intestine partly encircles what other digestive organ
Definition
the pancreas
Term
primary fcn of duodenum
Definition
“Mixing bowl” that receives:
chyme from stomach & digestive secretions from pancreas and liver
Term
other fcn of duodenum (besides absorption  of nutrients)
Definition

1. prevent damage the absorptive surfaces of the small intestine by secreting hormones that:

 

1.neutralizing the acids

 2.regulating stomach activity

 

aka it sends out differnet enzymes with respect to whatever is in the chyme.

Term
how can ulcers develope ?
Definition
sm intestine is exposed to gastric juice (duodenum doesnt neutralize it)
Term
how does pancreas protect itself from stomach acid?
Definition
Enzymes from the pancreas have a basic pH to counteract the stomach acids.
Term
the middle segment of small intestine is
Definition
jejunum
Term
which sm intestine segement can be removed to promote rapid weight loss, why?
Definition
jejunum,
Is the location of the most:
•Chemical digestion
•Nutrient absorption
Term

give the histology of the jejunum

 (2)

Definition

Has few plicae circulares •

 

most developed Small intestinal villi 

Term
plicae circulares & intestinal villi def & fcn
Definition
1•Circumferential folds in the mucosa and submucosa (increases surface area)

2.simple coulmnar epithelium covered with microvilli

both increase surface area
Term
The final segment of small intestine
Definition
ileum, the LONGEST
3.5 meters (11.48 ft) long
Term
what structure Differentiates the ileum from duodenum and jejunum in humans?

name &def
Definition
Peyer patches (aggregated lymphoid nodules)
Term
the ileum ends at the
Definition
ileocecal valve
Term
ileocecal valve
Definition
A sphincter that controls flow of material from the ileum into the cecum of the large intestine
Term
each villus of sm intestine contains (4)
Definition

1.capallaries

2.brush border

3.mucous cells  

4.lacteal

Term
Brush border enzymes
Definition
Integral membrane proteins located on the surface of intesintal microvilli
Term
Brush border enzymes fcn
Definition
Break down materials that it comes in contact with
Term
Brush border enzymes include (4)
Definition
1.aminopeptidases,
2.maltase,
3.sucrase,
4.lactase.
Term
Enteropeptidase aka
Definition
Enterokinase
Term
what kind of enzyme is Enteropeptidase
Definition
A brush border enzyme
Term
Enteropeptidase what Activates pancreatic proenzyme
Definition
tryspinsogen (enteropeptidase activates trypsinogen to become trypsin)
Term
•_______________ digests proteins and activates _________ (3)
Definition
1. trypsin
2.pro enzymes of:
carboxypeptidase
chymotrypsin
elastase
Term
procarboxypeptidase fcn
Definition
Protease that hydrolyzes peptide bonds at the C-terminal of the protein
Term
aminopeptidase fcn
Definition
Protease that hydrolyzes peptide bonds at the N-terminal of the protein
Term

Enteroendocrine cells fcn

 

include 3 ex

Definition

produce intestinal hormones such as :

 

1.gastrin

2.cholecystokinin

3.secretin

Term
Watery intestinal juice
how many liters of watery intestinal juice enters the intestinal lumen per day?
Definition
1.8 L
Term
Watery intestinal juice fcn (3)
Definition

1•Moisten chyme

2•Assist in buffering acids

3.Keep digestive enzymes and products of digestion in solution

Term
what Stimulates peristalsis and secretion Along entire small intestine?(1) give name& aka
Definition
Gastroenteric/Myenteric Reflex
Term
what Triggers the relaxation of ileocecal valve
Definition
gastroileal reflex
Term
gastroileal reflex fcn
Definition
Allows chyme to pass from small intestine into large intestine (colon)
Term
how does the duodenum protect itself from the stomach's  chyme (in general)
Definition
releases various enteroendocrine enzymes such as CCK that will cause pancreas to relase bicarbonate.
Term
how does the duodeum protect iteself from the stomach's acidic chyme?
Definition
releases secretin which causes pancreas to release buffers .
Term

salivary amlyase breaks apart:

disaccaharides

monosaccaharides

or 

polysaccahrides

 

Definition
polysaccahrides
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