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Digestion V
Dr. Markos UCC
38
Physiology
Undergraduate 1
03/22/2017

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Cards

Term
Where does the majority of absorption take place
Definition
Duodenum and Jejunum
Term
What are Kerckrings folds
Definition
Fold of mucosa in the small intestine
Term
How are the microvilli often described
Definition
brush border membrane
Term
Name the enzyme that breaks the 1-4 glycosidic bond
Definition
alpha amylase
Term
What is maltotriose
Definition
3 glucose units linked by alpha 1,4 glycosidic bond.
Term
The most active site of a-amylase
Definition
Duodenum due to the alkaline environment and longer residence time of chyme in the small intestine
Term
Name 3 oligosaccharidases released in the small intestine
Definition
lactase
sucrase
isomaltase
Term
What type of transport is involved when galactose is taken into the epithelial cells
Definition
Active transport
Term
Name the transport protein responsible for glucose uptake into the epithelial cells
Definition
SGLT1
Term
Name a monosaccharide other than glucose that is taken up by the SGLT1
Definition
Galactose
Term
How is fructose absorbed by the epithelial cells
Definition
Facilitated diffusion via GLUT 5
Term
Name the transport protein that moves fructose out of the epithelial cell
Definition
GLUT2
Term
Where does protein digestion being
Definition
Stomach
Term
What enzyme starts digestion of protein
Definition
peptin
Term
Name the substance that activates the brush border enzymes responsible for protein digestion.
Definition
Enteropeptidases
Term
Name the brush border enzymes involved in protein digestion
Definition
Aminopeptidases
Dipeptideases
Dipeptidyl aminopeptidases
Dipeptidyl carboxypeptidases
Term
Why can't AA or short peptides diffuse though the membrane
Definition
They are not fat soluble
Term
How are individual AA transported across the cell
Definition
Transporters on brush border and basolateral membrane
Term
How are short peptides transported across the cell
Definition
Secondary active transport
Term
Name the fat soluble vitamins
Definition
A, D, E , K
Term
Where does lipid digestion begin
Definition
Stomach of neonates
Duodenum of adults
Term
Name the pancreatic lipases
Definition
Colipse
Pancreatic Lipase
Phophlipase A
Cholesterol ester hydrolase
Term
where are the pancreatic lipases active
Definition
Duodenum and Jejunum
Term
What reaction do triglycerides undergo after emulsification
Definition
Hydrolysis to fatty acids and monoglycerides and glycerol
Term
What enzymes hydrolyse lipids in the duodenum
Definition
Pancreatic lipase and colipase
Term
How are fatty acids absorbed
Definition
Diffusion
Term
How is cholesterol absorbed
Definition
Diffusion
Term
Name the product of fatty acid and monoglyceride reaction in epithelial?
Definition
Triglycerides
Term
Name 2 substituents of chylomicron
Definition
Triglycerides and protein.
Term
Where are chylomicrons stored?
Definition
Endoplasmic reticulum
Golgi Apparatus
Term
How do chylomicrons enter venous blood?
Definition
Via the thoracic duct of lymph system
Term
How do chylomicrons enter lacteal
Definition
exocytosis
Term
Name the protein substituent that binds to chylomicrons in venous blood
Definition
apolipopprotein. ApoE
Term
What is the function of chylomicron
Definition
To deliver dietary lipids to body cells
Term
Name the lipoprotein that contributes to athersclerosis
Definition
Low Density Lipoprotein
Term
Name the lipoprotein that delivers endogenous triglycerides to body cells
Definition
Very Low Density Lipoprotein
Term
How is VLDL converted to LDL
Definition
Removal of triglycerides
Term
Name the lipoprotein that takes up phospholipids and free cholesterol from blood vessels
Definition
High density lipoprotein
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