Term
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Definition
Inadequate insulin activity, due to either inadequate production of insulin or to decreased responsivness of body cells to insulin. |
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Term
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Definition
dominant hormone when blood glucose level is high. Stores energy- binding to receptor sites , changing the permeability of the membrane such that glucose enters the cell more readily.
"Transports Glucose" |
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Term
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Definition
- Dominate hormone when blood glucose is low
- produces energy
- acts on liver to increase glycogenolysis ( conversion of glycogen into glucose)
- in extreme cases= Gluconeogenesis ( break down of protein and fat into glucose)
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Term
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Definition
the breakdown of glycogen to glucose |
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Term
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Definition
Conversion of protein and fat to form glucose |
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Term
What does Alpha, Beta and delta cells of the pancreas do? |
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Definition
- Alpha: Produces glucogon
- Beta: produces Insulin
- Delta: Somastatin ( inhibits glucogon and insulin)
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Term
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Definition
Compounds produced during the catabolism of fatty acids, including acetoacetic acid, B-hydroxybuyric acid and acetone. |
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Term
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Definition
the presense of significant quantities of ketone bodies in the blood |
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Term
What is Type 1 Diabetes Mellitus ( IDDM)? |
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Definition
- very low production of insulin by the pancreas
- require insulin injections
- heredity is a factor for determining who will be predisposed to type 1
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Term
What is Type 2 Diabetes (NIDDM)? |
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Definition
- moderate devline in insulin production
- increased weight (increased size of fat cells) causes a relative deficiency in the number of insulin receptors per cell, making fat less responsive to insulin
- more common
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Term
What is the emergency? Signs and symtoms:
- Polyuria, polydipsia, polyphagia
- warm, dry skin
- N/V
- Kussmauls resps
- fruity odor on breath
- tachycardia
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Definition
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Term
Explain Diabetic Ketoacidosis ( Diabetic Coma) |
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Definition
- complication of type 1 diabetes
- profound insulin deficiency with increased glucagon activity
- body uses gluconeogensis- creates ketones
- changing the Ph to more acidic
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