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Diabetes Mellitus can cause: |
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Steroids make glucose increase or decrease? |
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-Transports and metabolizes -stimulates storage of extra glucose -signals to the live to stop release of glucose |
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-Enhances storage of dietary fat/adipose -Accelerates transport of amino acid into cells -Inhibits breakdown of stored glucose |
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Where is insulin released? |
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breakdown of stored glucose |
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genetics, HLA (Human Leukocyte Antigen), Autoimmune response, viruses and toxins |
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-destruction of pancreatic beta cells -decreased insulin production -fasting and postprandial (after meal) hyperglycemia |
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Thin, <30 yrs old, islet cell antibodies, lack of endogenous insulin Hyperglycemia, DKA (diabetic Ketoacidosis), n/v, abdominal pains |
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Glucosuria, glucose in blood exceeds renal threshold, osmotic diuresis, glycogenolysis, gluconeogenesis, ketones |
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all water is pulled out of the body |
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breakdown of stored glucose |
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breakdown of amino acids and other substances |
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Slow onset, insulin resistance, impaired insulin secretion |
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fatigue, irritability, polyuria, polydipsia, poor healing wounds, vaginal infections, blurred vision, hyperglycemia (HHNS) |
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Hyperglycemic Hyperosmolar Nonkinetic Syndrome (HHNS) |
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is a huge amount of osmotic diuresis |
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diet, weight reduction, physical activity |
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Diabetes Mellitus risk factors |
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family history, obesity, race/ethnicity, age, history of impaired fasting glucose or glucose tolerance, Hypertension, HDL cholesterol <35mg/dl, triglyceride >250mg/dl, history of gestational diabetes or baby > 9lbs |
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Diabetes classic clinical manefestations |
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Three P's, fatigue, weakness, vision changes, numbness in hands and feet, dry skin, slow healing wounds, recurrent infections |
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skipped meals, too much insulin |
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Mild:Tachycardia, nervousness, hunger Moderate: concentration issue, headache, confusion, slurred speech Severe:disoriented, seizures, decrease LOC |
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15 grams of fast acting carbs |
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before meals and at bedtime |
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drink something sweet and then test |
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reveals BG levels for the past 3 months normal 4-6% Diabetic pt <7% |
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