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Diabetes Pramlintide
Diabetes Pramlintide
13
Pharmacology
Professional
09/14/2012

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Cards

Term
How does pramilintide work?
Definition

Synthetic analog of the human neuroendocrine hormone, amylin. Amylin is produced by pancreatic beta cells to assist in postprandial glucose control. Amylin helps slow gastric emptying, prevents an increase in serum glucagon following a meal, and increases satiety

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Term
Brand name for Pramlintide?
Definition
Symlin
Term
Does Pramlintide cause hypoglycemia?
Definition
Yes!
Term
How does pramlintide affect diabetic dosing?
Definition

For both type 1 and 2 DM: decrease meal - time insulins by 50% when starting this drug

Term
Black box warning
Definition

Co-administration with insulin may induce severe hypoglycemia (usually within 3 hours following administration)

Term
Do patients normally experience nausea?
Definition

Nausea in over 30% patients esp on iniation, so titrate carefully.

Term
[image]
Definition
Statement. Not a question.
Term
Should pramlintide be mixed with insulin?
Definition
Never mix in the same syringe with insulin
Term
How in pramlintide injected?
Definition

The same as insulin. Inject under the skin (SC)

 

Term
What to do when a dose is missed?
Definition
Wait until the next meal and take your usual dose at the next meal.
Term
When not to take this medication when eating?
Definition

Do not take if a meal of fewer than 250 calories or 30 grams of carbohydrates is eaten.

 

Do not use if you skip a meal

Term
Can this medication be refrigerated?
Definition

Opened vials can be refrigerated or kept at room temperature for up to 28 days. Pens are good at room temp for 30 days.

Term
The most common side effect of pramlintide?
Definition
nausea
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