Shared Flashcard Set

Details

Diabetes drugs
Medchem II
11
Other
Not Applicable
04/18/2012

Additional Other Flashcards

 


 

Cards

Term
Sulfonylurea
Definition
  • Hypoglycemic agent
  • Promote insulin release (independent)
  • Inhibit Glucagon secretion
Term
Meglitinide
Definition
  • Hypoglycemic agent
  • Promote insulin release (dependent)

"me too!"

Term
Biguanide
Definition
  • Non Hyperglycemic
  • Inhibit glucose production
  • Increase GLUT-IV

"big drug"

Term
Glitazone
Definition
  • Post receptor effect
  • Bind PPAR γ-> ↑ GLUT-4 synthesis

(Insulin more effective)

"glitter"

Term
α-glycosidase inhibitor
Definition
  • Decrease postprandial spike
Term
Octreotide
Definition

Somatostatin

  • treat sulfonylurea OD
Term

Amylin agonist

 

Definition
  • ↓ Gastric emptying
  • ↓ Glucagon secretion
  • ↓ Caloric intake
Term
GLP-1 Agonist
Definition
  • ↑ Insulin secretion
  • ↓ Glucagon & somatostatin
  • Satiety

"Gila monster"

Term
DPP-IV inhibitor
Definition

Inhibit breakdown of GLP-1

  • ↑ Insulin secretion
  • ↓ Glucagon secretion
Term
D2 agonist
Definition
↓ hepatic production of glucose
Term
Aldose Reductase Inhibitors
Definition
Prevents glucose -> sorbitol.
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