Term
| How do α-glucosidase inhibitors work? |
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Definition
Inhibits alpha-glucosidase in the intestine and alpha - amylase in the panreas resulting in delayed absorption of glucose. Inhibits metabolism of sucrose to glucose and fructose
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Definition
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| Do alpha-glucosidase inhibitors decrease pre or post prandial blood glucose? |
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Definition
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Term
| When are alpha - glucosidases inhibitors taken? |
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Definition
both acarbose and miglitol are started at 25 mg with the first bite of each main meal |
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Term
| Side effects of alpha - glucosidase inhibitors? |
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Definition
Gi effects (flatulence, diarrhea)
Increases HDL and decreases TG
Weight neutral |
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Term
| When are alpha - glucosidase inhibitors contraindicated? |
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Definition
Irritable bowel syndrome (IBS); intestinal obstruction - do not use with any significant GI disease |
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Term
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Definition
| Statement. Not a question. |
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Term
| Should an alpha glucosidase inhibitor be taken when a meal is skipped? |
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Definition
| No. skip a meal, skip a dose |
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Term
| Do alpha glucosidase inhibitors cause hypoglycemia? |
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Definition
NO. These agents, by themselves, do not cause low blood sugar. |
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Term
| What should one do if they experience low blood sugar while on an alpha glucosidase inhibitor? |
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Definition
low blood sugar after taking acrabose or miglitol CANNOT be treated with sucrose (present in fruit juice) or with table sugar or candy. Must treat hypoglycemia with a glucose tablet or gel.
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