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Definition
Damage to the pit gland or hypothalamus |
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Defect in kidney tubules, genetic, or drug induced kidney damage |
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Which drugs can increase chances of DI |
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Placenta makes enzyme that destroys ADH, |
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Kidneys unable to respond to ADH, or a lack of ADH leads to large volumes of dilute urine |
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Definition
Polyuria Polydipsia Nocturia Muscle weakness Bed wetting in children Dry skin (s/s of dehydration Dizziness Fatigue Nausea |
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<200-300
/below 400. different on two different sources |
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i/o treatment NOT working: |
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DDAVD (synthetic ADH) Diuretic (HCTZ) will actually reduce urine output by stimulating aldosterone to work in tubules Oral fluid replacement if possible! |
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0.1/0.2 mg tablets
Max: 1.2 mg daily |
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Foods/drinks to stay away from? |
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Caffiene! Natural diuretics such as watermelon |
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Definition
Daily wt LOC monitoring (seizure risk) Assess: urine (pale, is it improving?) thirst, hydration status (mucous membranes, skin turgor) Strict I/O! Any hx of trauma, infection, head injury, chronic diseases (KD?) |
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CT/MRI to rule out trauma, injury, tumor. Ultrasound, kidney labs to rule out structural damage/inflammation Water deprivation test: stop drinking fluids and check ADH (rarely performed) |
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Extreme dehydration with rapid water loss Confusion, seizures, coma Changes in LOC, heart rhythm |
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