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Developmental Toxicology
N/A
28
Anthropology
10th Grade
02/09/2013

Additional Anthropology Flashcards

 


 

Cards

Term
abnormal fetal development caused by in utero exposure to chemical agents or other conditions (eg. pathogens, nutrition, etc)
Definition
developmental toxicology
Term
agent that causes structural or functional defect
Definition
teratogen
Term
Rubella: post natal infection
Definition
rash
Term
Rubella contracted while pregnant
Definition
CRS: cataracts, blindness, deafness, mental retardation
Term
used to control morning sickness in pregnancy in 1950s; never approved in US
Definition
Thalidomide
Term
NOT a good barrier against chemicals
Definition
placenta
Term
pregnant mother after chemical exposure
Definition
increased respiration, metabolism changes, increased absorption of some minerals
Term
Relatively resistant
Definition
Preimplantation (week 1,2)
Term
Most sensitive-- structural defects)
Definition
Embryonic period (week 3-month 3)
Term
growth; toxins will cause suppressed growth or functional impairment
Definition
fetal period (final 6 months)
Term
Mechanisms of toxicity
Definition
oxidative stress, interfering with DNA or protein synthesis, interfering with cell proliferation or apoptosis
Term
synthetic non-steroidal estrogen used to prevent miscarriage
Definition
Diethylstilbestrol (DES)
Term
Derivatives of vitamin A Isotretinoin
Definition
Retinoids
Term
retinoids
Definition
causes malformations: face/limbs/skeleton, heart, CNS, fetal death
Term
only occurs in children of full blown alcoholics
Definition
fetal alcohol syndrome
Term
wide range of manifestations; reduced birth weight, milder behavioral/neurological disorders
Definition
fetal alcohol spectrum disorder
Term
toxic to developing nervous system
Definition
mercury/organic or methyl mercury
Term
in utero exposures that are heritable to many subsequent generations
Definition
transgenerational effects
Term
altered hormone function causes change in offspring (or the person exposed); Ex: xenoestrogens, anti-estrogens, anti-androgens
Definition
Endocrine disruption
Term
Mechanisms of toxicity
Definition
oxidative stress, interfering with DNA or protein synthesis, interfering with cell proliferation or apoptosis
Term
synthetic non-steroidal estrogen used to prevent miscarriage
Definition
Diethylstilbestrol (DES)
Term
Derivatives of vitamin A Isotretinoin
Definition
Retinoids
Term
retinoids
Definition
causes malformations: face/limbs/skeleton, heart, CNS, fetal death
Term
only occurs in children of full blown alcoholics
Definition
fetal alcohol syndrome
Term
wide range of manifestations; reduced birth weight, milder behavioral/neurological disorders
Definition
fetal alcohol spectrum disorder
Term
toxic to developing nervous system
Definition
mercury/organic or methyl mercury
Term
in utero exposures that are heritable to many subsequent generations
Definition
transgenerational effects
Term
altered hormone function causes change in offspring (or the person exposed); Ex: xenoestrogens, anti-estrogens, anti-androgens
Definition
Endocrine disruption
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