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Developmental Disturbances #4
Oral Pathology
68
Dentistry
Professional
08/03/2013

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Term
Cyst definition
Definition
Pathologic cavity lined by epithelium and often containing a fluid or semi-solid material
Term
Palatal cysts of newborn definition
Definition
Small developmental inclusion cysts on palate (or alveolar ridge) of newborn arising from different types of epithelial remnants
Term
Types of Palatal Cysts of the Newborn
Definition
Epstein's pearls, Bohn's nodules, Dental lamina cysts
Term
Epstein's pearls (type of Palatal cyst of newborn)
Definition
Along median palatal raphe derived from epithelium entrapped during fusion of palatal shelves to form secondary palate
Term
Bohn's nodules (type of Palatal cysts of newborn)
Definition
Scattered over hard palate, often near junction w/ soft palate derived from ducts of accessory salivary glands
Term
Dental lamina cysts (type of Palatal Cysts of newborn)
Definition
On alveolar ridges derived from dental lamina remnants
Term
Histological features of palatal cysts of newborn
Definition
Keratin filled cysts lined by stratified squamous epithelium
Term
How common are palatal cysts of newborn?
What are the clinical features?
Definition
65-85% if all neonates
1-3 mm white or yellow-white papules
Term
Treatment and prognosis of palatal cysts of the newborn
Definition
No treatment
Good - generally disappear
Term
Other names for Nasolabial cyst
Definition
Nasoalveolar cyst
Klestadt cyst
Term
Definition of Nasolabial cyst
Definition
Rare developmental cyst occuring in upper lip lateral to midline
Term
Pathogenesis theory 1 of nasolabial cyst
Definition
fissural cyst from epithelial remnants trapped along line of fusion of maxillary, median nasal and lateral nasal processes (prob. not this one)
Term
Pathogenesis theory 2 of nasolabial cyst
Definition
derived from misplaced epithelium of nasolacrimal duct
Term
Clinical features of nasolabial cyst
Definition
swelling of upper lip lateral to midline causing elevation of ala of nose
Term
Consequence of nasolabial cyst
Definition
Often elevates mucosa of nasal vestibule, obliterates max mucolabial fold and may cause nasal obstruction or interfere with wearing of denture
Term
Incidence of nasolabial cyst
Definition
Most common in adults
Female predominance (3/1)
10% bilateral
Term
Radiographic features of nasolabial cyst
Definition
generally absent except occasional faint lucency due to pressure resorption of underlying bone
Term
Histologic features of nasolabial cyst
Definition
(true cyst) most commonly lined by pseudostratified columnar epithelium, often with goblet cells and cilia (respiratory)
May be cuboidal or squamous metaplasia
Term
Treatment and prognosis of nasolabial cyst
Definition
Complete surgical removal
Good, recurrence rare
Term
Globulomaxillary cyst definition
Definition
Originally described as developmental cyst in maxilla in region b/t lateral and canine teeth and arising from epithelium entrapped during fusion of globular portion of median nasal process with maxillary process
Term
How does a globulomaxillary cyst present radiographically?
Definition
Pear-shaped (b/t maxillary lateral and canine)
Term
Current definition of globulomaxillary cyst
Definition

Clinicopathologic presentation of a variety lesions, mostly odontogenic cysts but include some others

(Virtually all contemporary studies demonstrate non-embryologic origins, most commonly odontogenic)

Term
Characteristics of globulomaxillary cysts
Definition

Histologic features depend on actual entity

Cysts in this position do demonstrate some respiratory type epithelium probably because proximity to sinus lining

True fissural globulomaxillary cyst prob does not exist

Term
Nasopalatine duct cyst is also known as...
Definition
Incisve canal cyst
Term
Definition of Nasopalatine cyst
Definition
Developmental cyst arising from remnants of nasopalatine duct, an embryologic structure connecting oral and nasal cavities in area of incisive canal
Term
How common is Incisve canal cyst?
Definition

Most common non-odontogenic cyst ~1% of population

4th-6th decade of life

Predominantly male

Term
Most common S&Ss of Nasopalatine duct cyst
Definition

may be long-standing & intermittent - swelling of anterior palate, drainage, pain

Many asymptomatic, detected on radiographs

Term
True or False: Nasopalatine duct cyst usually results in nonvital teeth.
Definition
False, teeth are usually vital
Term
Radiographic shape of nasopalatine duct cyst
Definition
Oval/round; Heart-shaped
Term
Radiographic features of nasopalatine duct cyst
Definition
Often with sclerotic border, located at or near midline of anterior maxilla b/t or apical to central incisors
Term
Can root resorption be seen in nasopalatine duct cyst?
Definition
Yes
Term
What is is called if nasopalatine duct cyst is confined to soft tissue?
Definition
Cyst of incisive papilla
Term
Histologic features of nasopalatine duct cyst
Definition

lined by stratified squamous epithelium, pseudostratified columnar ciliated, simple columnar, simple cuboidal or any combination

Wall of cyst often contains nerves, blood vessels, occasional lobules of mucous glands, small islands of cartilage and chronic inflammation

Term
Treatment and Prognosis of nasopalatine duct cyst
Definition

Surgical enucleation w/ or following microscopically documented diagnosis

Good

Term
Median palatal cyst definition
Definition

Rare fissural cyst theoretically developing from epithelium entrapped along embryonic line of fusion of lateral palatal shelves of maxilla

(some if not most may represent posteriorly positioned nasopalatine duct cyst)

Term
Clinicoradiographic features of median palatal cyst
Definition

Firm or fluctuant swelling of midline of hard palate posterior to palatine papilla

Well-circumscribed radiolucency in midline of hardpalate, occasionaly diverging roots of centrals

Term
Who exhibit median palatal cysts seen?
Definition

Most common in young adults

Male just as likely as female

Term
Histologic features of median palatal cyst
Definition
lined by stratified squamous epithelium, occasionally respiratory (pseudostratified columnar ciliated)
Term
Treatment and prognosis of median palatal cyst
Definition

Surgical excision

Good

Term
Definition of median mandibular cyst
Definition
Non-inflammatory cyst occuring in midline of mandible
Term
Theory of median mandibular cyst
Definition
fusion does not occur - just filling out of isthmus, no epithelium exists to be entrapped
Term
What type of cyst do median mandibular cysts represent?
Definition
Odontogenic - should be managed as such
Term
Defintion of follicular cysts of skin
Definition
Common keratin-filled lesions arise from one or more portions of hair follicle
Term
Most common type of follicular cyst?
Definition
Epidemoid or infundibular cyst
Term
Prevalence of eidemoid cysts
Definition
80% of follicular cysts
Term
Most common location for follicular cysts
Definition
Acne prone areas (head, neck, and back)
Term
Histology of follicular cysts
Definition
stratified squamous epithelium, granular cell layer then cavity filled with degenerating orthokeratin
Term
Treatment and prognosis of follicular cyst (epidemoid)
Definition

Conservative surgical excision

Good

Term
Dermoid cyst description
Definition
benign cystic teratoma
Term
Histologic features of dermoid cyst
Definition
Lined by epidermis-like epithelium and contains dermal adnexal structure in cyst wall
Term
Most common location of dermoid epithelium
Definition
Midline of floor of mouth
Term
Type of epithelium dermoid cyst is lined with
Definition
orthokeratinized stratified squmous epithelium w/ prominent granular cell layer
Term
Treatment of dermoid cyst
Definition
Surgical removal
Term
Thyroglossal duct cyst definition
Definition
developmental cyst arising from epithelial remnants of embryonic thyroglossal duct
Term
Thryoglossal duct cyst occurs in...
Definition
1st 2 decades of life; 50% before age 20; no gender predilection
Term
Location of thyroglossal duct cyst
Definition
occur anywhere along thyroglossal duct from foramen cecum area to suprasternal notch
Term
Characteristics of thyroglossal duct cyst
Definition

Usually painless, fluctuant movable swelling unless secondarily infected; lesions at base of tongue may cause laryngeal obstruction

If cyst maintains attachment to hyoid bone or tongue, it will move vertically during swallowing or protrusion of tongue

Term
Features of thyroglossal duct cyst
Definition

Most smaller than 3 cm, may reach up to 10

Fistulous tract to skin or mucosa may develop, usually from rupture of infected cyst or following surgery

Term
Histologic features of thyroglossal duct cyst
Definition

cyst usually lined by columnar or stratified squamous epithelium

Thyroid tissue may be present

Term
Treatment and prognosis of thyroglossal cyst
Definition
surgical removal of cyst + midline segment of hyoid bone and adjacent muscle
Good (papillary thyroid carcinoma develops in 1% of cases)
Term
Another name for cervical lymphoepithelial cyst is...
Definition
Branchial cleft cyst
Term
Definition of cervical lymphoepithelial cyst
Definition
Developmental cyst of lateral neck though to arise from remnants of branchial clefts
Term
Alternate theory to cervical lymphoeptihelial cyst
Definition
development of cystic changes in parotid gland epithelium entrapped in upper cervical lymph nodes during embryonic life
Term
Prevalence of cervical lymphoepithelial cyst
Definition
20-40 y/o
Gender is equal
Term
Clinical features of cervical lymphoepithelial cyst
Definition

Soft fluctuant mass 1-10 cm in diameter in upper lateral neck along anterior bord of SCM m

2/3 on left, 1/3 on right occasionally bilateral

Term
Are cervical lymphoepithelial cysts painful?
Definition
May be associated with pain or tenderness due to secondary infection
Term
Histologic features of branchial cleft cyst
Definition
true cysts lined by stratified squamous (90%) or respiratory (10%) epithelium
Term
Treatment and prognosis of cervical lymphoepithelial cyst
Definition

Complete surgical removal

Good (Rare cases of malignant transformations arising in epitheliulm of CLEC; pre-surgical biopsy can be useful to r/o malignancy)

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