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Developmental Biology
Developmental Terms and Ethical Views
29
Biology
Undergraduate 1
02/28/2011

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Term
Plato's views on beginning of human development?
Definition
ENSOULMENT begins at birth. Also believed in DUALITY, or soul and body as separate entities
Term
Aristotle's view on beginning of human development?
Definition
ANIMATION of males at 40 days, 90 days for females (the fetus begins to look human)
Term
What is QUICKENING?
Definition
Point English Common law designated a fetus human. Refers to when fetus 'kicks'
Term
What are traditional Jewish views on beginning of human development?
Definition
Full status of human at 'crowning' during birth. Abortion can be used as a final result when the mother's life is in danger.
Term
Roman Catholic Church's position on human development?
Definition
Human at conception. Abortion is absolutely forbidden.
Term
Islamic view of early human development?
Definition
Abortion alright before first 120 days; must have father's permission.
Term
What are some scientific views of when humans take on souls?
Definition
(1) Fertilization: have a novel genome (but doesn't even a skin cell have all the DNA in the body?)

(2)At gastrulation: cell differentiation begins, starts to form 'identity'

(3)Acquisition of EEG pattern: if losing EEG is death, acquiring is birth

(4)At or near birth: when become independent of mother's body
Term
Why might a couple want to determine the sex of their child?
Definition
One or both parents could carry a sex-linked (X chromosome) disease, so having a girl would prevent the child from carrying the disease.

Also, they might want to 'family balance.'
Term
What can be a disadvantage of widespread sex determination, as seen in some Asian countries?
Definition
A large gender gap, some as wide as 120 boys - 100 girls
Term
Where is nonmedical sex selection banned?
Definition
Over 40 European countries and India. US has not banned, and does not have many regulations on sex selection.
Term
What is special about the "23rd chromosome?"
Definition
It is the one that determines sex, and is either X or Y.
Term
What differentiates boys and girls in chromosomes?
Definition
XX is a girl, XY is a boy
Term
Do sperm have X or Y chromosomes?
Definition
Half have X, half have Y
Term
Are gonads female or male from the start?
Definition
Gonads develop in the BIPOTENTIAL STAGE, having neither male nor female characteristics.
Term
Describe gamete precursors to male development?
Definition
Internal male sex cords become Sertoli cells of SEMINIFEROUS tubes, loose tissue becomes LEYDIG CELLS.
Term
Describe game precursors to female development?
Definition
Granusola cells and thecal cells develop and become FOLLICLES to envelop eggs.
Term
How does male develop in secondary sex selection stage?
Definition
Sertoli cells secrete ANTI-MULLERIAN DUCT HORMONE (AMH) to destroy Mullerian duct. Leydig cells secrete TESTOSTERONE to inhibit breasts, etc
Term
How does a female develop in secondary sex selection stage?
Definition
Ovaries produce ESTROGEN to continue developing Mullerian duct. The Wolffian duct with degenerate.
Term
Describe X-linked diseases?
Definition
X chromosomes can carry some diseases, such as androgen insensitivity syndrome. Boys are more at risk because, having XY, they do not have a normal X chromosome to balance a bad one if they receive it. Girls who receive one bad X chromosome will be 'balanced out' by the other good X chromosome.
Term
How can we use prenatal techniques to check for X-linked diseases?
Definition
sperm selection
Term
What prevents polyspermy?
Definition
CORTICAL GRANULES
Term
Describe parts of sperm?
Definition
ACROSOME in head carries enzymes needed to cause an ACROSOMAL REACTION and digest through egg's zona pellucia. MITOCHONDRIA gives energy. FLAGELLUM propels to egg
Term
What is capicitation?
Definition
Final stage where sperm is 'activated' because of chemical change in female reproductive tract and starts swimming.
Term
Describe parts of egg?
Definition
From outside: CUMULUS
ZONA PELLUCIDA: protein matrix
CELL MEMBRANE
POLAR BODY: from meotic division
OVUM
Term
Why can IVF cause higher ratios of multiple births than natural fertilization?
Definition
Multiple eggs are implanted because of the chance that they will not all come full term. A woman's age can help determine the chances that one of them will develop.
Term
Describe the female hormonal cycle?
Definition
Pituary gland has FSH, LH. Carries these to ovary. Ovary produces estrogen and progesterone; used to develop uterine lining. Uterine lining is shed during MENSES. FSH increases and makes follicles mature, LH to promote oocyte . Estrogen triggered up. Estrogen = LH, FSH up. Toward end PROGESTERONE increases, pituary decreases
Term
How do birth control pills work?
Definition
They contain PROGESTERONE, with blocks ovulation by decreasing FSH and LH in the pituary gland.
Term
Describe some Assisted Reproduction methods?
Definition
(1)In Vitro Fertilization: combine sperm and eggs in petri dish, select most fertile looking
(2) hormonal therapies: to increase ovulation
(3) artifical insemination: inject sperm into uterus
Term
What is parthenogenesis?
Definition
An egg developing without being fertilized.
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