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Development Lecture 3
Medical School Human Development Class
58
Medical
Graduate
10/09/2010

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Term
What are the most important structures involved in head and neck development?
Definition
Pharyngeal arches
Term
What structures are found within pharyngeal arches?
Definition
Muscles, bones, arteries, nerves, and CT
Term
Where are the structures found in pharyngeal arched derived from?
Definition
Neural crest and head mesoderm
Term
When does the oropharyngeal membrane rupture, allowing communication btwn the nasal and oral cavities
Definition
Day 26
Term
What is the anterior lobe of the pituitary gland derived from
Definition
oral ectoderm
Term
Rathke's Pouch
Definition
a dorsal diverticulum (evagination) formed near the junction of the oral cavity and pharynx that forms the anterior lobe of pituitary gland
Term
Crainopharyngiomas
Definition
tumors that form from remnants of the hypophysial (pituitary) diverticulum. tumor can compress optic chiasm, pt can have endocrine problems
Term
Cyst
Definition
abnormal sac containing containing gas, fluid or semisolid material
Term
sinus
Definition
space that opens into epithelium of origin
Term
fistula
Definition
abnormal passage leading from cavity/organ to surface of another cavity, organ. connects two epith lined surfaces
Term
What bones are derived from the maxillary process of the first arch
Definition
maxillary, zygomatic, palatine and squamous temporal bones
Term
What bone is derived from the mandibular process of the first arch
Definition
Mandible
Term
What bones and ligament are derived from Meckel's cartilage of the first arch
Definition
Malleus and incus; sphenomandibular ligament
Term
What muscles are derived from the first arch
Definition
Muscles of mastication, anterior belly of the digastric, tensor palatini, tensor tympani
Term
What cranial nerve is derived from the first arch
Definition
CN V- trigeminal
Term
What artery is derived from the first arch
Definition
maxillary artery
Term
What bones and ligament are derived from the second pharyngeal arch
Definition
Stylohyoid ligament; styloid process, upper 1/2 of hyoid bone body adn the lesser horns, stapes
Term
What muscles are derived from the second arch
Definition
Muscles of facial expression, posterior belly of digastric, stapedius, stylohyoid
Term
What cranial nerve is derived from second arch
Definition
CN VII Facial
Term
What artery is derived from second arch
Definition
external carotid
Term
What bones are derived from the third arch
Definition
lower 1/2 of hyoid bone body and greater horns
Term
What muscle is derived from the third arch
Definition
stylopharyngeus
Term
what muscles are derived form the third arch
Definition
Stylopharyngeus
Term
what cranial nerve is derived from the third arch
Definition
CN IX Glosspharyngeal
Term
What artery is derived from the third arch
Definition
Internal carotid
Term
What cartilage is derived from the fourth and sixth arches
Definition
laryngeal cartilage
Term
What muscles are derived from the fourth and sixth arches
Definition
Pharyngeal and laryngeal mm; palatoglossus, palatopharyngeus, levator palatini, striated muscle of esophagus
Term
What cranial nerve is derived from the fourth and sixth arches
Definition
X
Term
What artery is derived from the fourth and sixth arches
Definition
Aortic trunk
Term
What does the first pharyngeal groove become
Definition
External auditory meatus
Term
Where is a branchial cyst found
Definition
on the lateral neck, anterior to anterior edge of SCM
Term
What do the Lateral Lingual Swellings (tongue buds) and the Median Lingual Swelling (median tongue bud, tuberculum impar)become
Definition
the anterior 2/3 (or body) of the tongue
Term
What does the hypopharyngeal eminence become on the tongue
Definition
the posterior 1/3 of tongue
Term
Anklyoglossia
Definition
occurs when frenulum (under-connection of tongue to floor) is short and connects all the way to the tip of the tongue. Tongue is not able to move much
Term
what causes the choanae to be relocated to a more dorsal position
Definition
formation of hard and soft palate
Term
Dacryostenosis
Definition
failure of canalization of the nasolacrimal duct
Term
What is the cause of lateral cleft lip
Definition
Failure of MaxP and Medial nasal prominences to merge
Term
What is the cause of median cleft lip
Definition
failure of medial nasal processes to fuse
Term
What is CHARGE syndrome
Definition
Coloboma, Heart defects, choanal Atresia, Retardation, Genital hypoplasia, Ear anomalies
Term
Mandibulofacial Dysostosis
Definition
Clefts of structures derived from first arch
Term
Apert's syndrome
Definition
Tower skull, flat midface area, syndactyly (digits are fused), cleft palate, variable intelligence
Term
Stomedeum
Definition
precursor to mouth in embryo
Term
Hypertelorism
Definition
eyes too far apart
Term
hypotelorism
Definition
eyes too close
Term
What is the critical period for formation of the palate
Definition
weeks 6-9
Term
Foramen Cecum
Definition
site on back of tongue where thyroid gland descended
Term
where are the salivary glands derived from
Definition
oral ectoderm
Term
where would you find a thyroglossal duct cyst
Definition
anywhere along the displacement of the thyroid along midline of neck. Is mobile and moves when swallowing.
Term
What condition is a common result of thyroid agenesis?
Definition
Cretinism
Term
What pharyngeal pouch remains connected to the pharynx
Definition
first pouch
Term
What pharyngeal pouch forms lining of auditory tube
Definition
first pouch
Term
What pharyngeal pouch becomes infiltrated with lymphocytes
Definition
the second pouch (talking about palatine tonsils)
Term
What pharyngeal pouch associates with T lymphocyte precursors
Definition
The third pouch
Term
What pharyngeal pouch becomes a parathyroid gland
Definition
the third pouch forms the inferior parathyroid gland and the fourth forms the superior
Term
What pharyngeal pouch receives C cell precursors
Definition
the ultimopharyngeal body of the fourth pouch
Term
What pharyngeal pouch has derivatives that associate with the thyroid glands
Definition
third and fourth pouch
Term
What pharyngeal pouch forms a structure that atrophies after puberty
Definition
talking about the thymus-- the third pharyngeal pouch
Term
What pouch does the palatine tonsil come from
Definition
2nd pouch
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