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Dermatology
Dermatology Terms for Exam I
104
Veterinary Medicine
Graduate
08/30/2009

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Term
primary lesion
Definition
initial eruption that develops spontaneously as a direct result of underlying disease, develop & disappear quickly
Term
pustule
Definition
small circumscribed elevation of skin containing purulent material, neutrophils usually predominate ("pimple")
Term
papule
Definition
small, solid elevation of skin up to 1 cm in diameter, can be palpated as a solid mass
can be red, ("rash")
Term
plaque
Definition
small solid elevation of the skin with a flattened top (> 1cm)
Term
nodule
Definition
circumscribed, solid elevation > 1cm in diameter that extends into deeper layers of the skin ("lump or bump")
Term
tumor
Definition
large mass that may involve any structure of the skin of SQ tissue ("lump or bump")
Term
cyst
Definition
epithelium-lined cavity containing fluid or a solid material
Term
vesicle
Definition
small sharply circumscribed elevation of skin filled with clear fluid ("blister")
Term
bulla
Definition
large (> 1cm) vesicle
Term
hemorrhagic bulla
Definition
bulla containing blood
Term
wheal
Definition
sharply circumscribed, raised lesion consisting of edema that usually appears and disappears within minutes or hours (no change in overlying skin or hair) ("hives")
Term
angioedema
Definition
huge wheal that is distensible ("swelling")
Term
macule
Definition
circumscribed, nonpalpable area characterized by change in color of the skin; < 1 cm in diameter
Term
patch
Definition
macule > 1 cm
Term
nevus
Definition
circumscribed developmental defect in the skin
ex: pigmented _____=mole
Term
epidermal collarettes
Definition
scale arranged in a circular rim of loose keratin flakes, represents the remnants of the roof of a vesicle, bulla, pustule or papule
Term
crusts
Definition
dried exudate, serum, blood, medications or excess scale ("scab")
Term
excoriation
Definition
superficial (epidermal) erosions or ulcers caused by self-trauma
Term
lichenification
Definition
thickening of the epidermis and/or dermis with exaggeration of the superficial skin markings
Term
erosion
Definition
shallow epidermal defect that does NOT penetrate the epidermal basal cell layer
Term
ulcer
Definition
break in the epidermis with exposure of the dermis (resulting from deep pathological process)
Term
scar
Definition
area of fibrous tissue that has replaced the damaged dermis or SQ tissue (usually alopecic, atrophic and depigmented or hyperpigmented)
Term
fissure
Definition
linear cleavage into the epidermis or through the epidermis to the dermis (usually occurs when skin is inelastic and subject to sudden swelling from inflammation or trauma)
Term
callus
Definition
thickened, rough hyperkeratosis, alopecic, often lichenified plaque (occurs over bony protuberances resulting from chronic, low-grade pressure)
Term
alopecia
Definition
partial or complete loss of hair
Term
scale
Definition
accumulation of loose fragments of the stratum corneum
Term
comedones
Definition
dilated hair follicle filled with cornified cells and sebaceous debris ("black head")
Term
follicular cast
Definition
accumulation of keratin & follicular material that adheres to the hair shaft extending above the surface of the follicular ostia
Term
hypopigementation
Definition
reduction or total loss of pigment in the skin or hair
Term
hyperpigmentation
Definition
increase in the amount of pigment in the hair or skin
Term
pruritis
Definition
unpleasant sensation in the skin that causes the desire to scratch
Term
seborrhea
Definition
excessive scaling
Term
seborrhea sicca
Definition
excessive scaling (dry scales & dry hair coat)
Term
seborrhea oleosa
Definition
excessive scaling (greasy/sticky scales & hair coat)
Term
fistula
Definition
sinus or abnormal passage leading from abscess to the surface
Term
abscess
Definition
circumscribed SQ collection of pus
Term
actinic
Definition
chemically active rays of the electromagnetic spectrum
Term
erythema
Definition
redness of the skin associated with inflammation
Term
furunculosis
Definition
inflammation secondary to rupture of hair follicle, usually pyogranulomatous
Term
pyotraumatic dermatitis
Definition
superficial, ulcerative inflammatory process caused by trauma, aka: "acute moist dermatitis" ("hot spot")
Term
pyotraumatic folliculitis
Definition
deep suppruative folliculitis usually a mainifestation of deep pyoderma
Term
intertrigo
Definition
surface irritation and inflammation caused by frictional trauma of skin rubbing against skin, aka "skin fold dermamtitis"
Term
pemphigus
Definition
pustular diseases in which autoantibodies are directed against desmosomal proteins of the viable epidermis
Term
pemphigus foliaceus
Definition
antibodies directed agaisnt desmosomal proteins present in the upper layers of the epidermis, results in subcorneal papules
Term
pemphigus vulgaris
Definition
antibodies directed against proteins present in the lower layers of the epidermis, results in ulcers & erosions
Term
juvenile cellulitis
Definition
granulomatous dermatitis of puppies affecting the skin of the face, pinnae, submandibular and prescapular lymph nodes
Term
hematoma
Definition
localized mass of extravasated blood that is relatively or completely confined to the dermis and/or SQ
Term
seroma
Definition
localized accumulation of serum within the dermis/subcutis
Term
acral lick dermatitis
Definition
"lick granulomas" psychodermatosis resulting from repeated self-trauma to a specific area caused by obessive-compulsive behavior
Term
mast cell tumor, cutaneous lymphoma, transmissible venereal tumor, cutaneous plasmacytoma, cutaneous histiocytoma, melanoma (can also be spindle cell)
Definition
example of round cell tumor
Term
fibroma/fibrosarcoma, neurofibrosarcoma, hemangiopericytoma, hemangioma/hemangiosarcoma, leiomyoma/leiomyosarcoma, melanomas (can also be round cell tumors), equine sarcoids
Definition
example of spindle cell tumors
Term
lipoma, liposarcoma
Definition
non-spindle cell mesenchymal tumors
Term
basal cell tumor, papillomatosis, sebaceous hyperplasia/adenoma, squamous cell carcinoma, hair follicle tumors, epitrichial or apocrine tumors
Definition
epithelial tumors
Term
primary closure
Definition
immediate direct closure
Term
delayed primary closure
Definition
delayed direct closure before onset of granulation tissue
Term
secondary closure
Definition
direct closure after onset of granulation tissue
Term
seconda intention
Definition
indirect closure by granulation tissue and epithelial contraction
Term
undermining
Definition
combination of blunt & sharp dissection underneath the subdermal plexus; can be used to separate granulation tissue from epithelium
Term
walking sutures
Definition
used to stretch the skin in small increments allowing tension to be distributed over several rows of sutures
Term
axial pattern flaps
Definition
pedicle flap that has direct cutaneous artery and vein at its base (direct vascular supply allows larger/longer flaps to survive)
Term
myocutaneous flap
Definition
flap composed of skin & muscle, used for deep reconstruction
Term
skin scraping, cytology, DTM culture
Definition
basic database for dermatology
Term
Flea Allergy Dermatitis
Definition
most common allergic skin disease in dogs and cats
Term
Type I & IV
Definition
hypersensitivity rxns involved in FAD
Term
1-3 years, or within several months of first flea exposure
Definition
age of onset for FAD
Term
tail base, rump, perineum, inner thighs
Definition
typical distribution of FAD
Term
Cullicoides
Definition
insect commonly implicated in insect hypersensitivity in horses
Term
insect hypersensitivity
Definition
most common allergic skin disease in horses
Term
ventral (axillae, groin, elbows), pinnae; can become generalized over time
Definition
distribution of lesions associated with Scabies in dogs
Term
tips of pinnae and head, progressing to trunk
Definition
distribution of lesions for Notoedres
Term
lime sulfur dips for 6-8 wks, weekly amitraz
ALL contact cats must be txed
Definition
tx for Notoedres
Term
1. insect control
2. symptomatic relief with oral prednisone
3. Antihistamines
4. Omega 3/omega 6 FA
5. Anti-pruritic shampoos
Definition
tx for insect hypersensitivity
Term
1. Flea control
2. symptomatic relief with oral prednisone
3. antihistamines
Definition
tx for flea allergy dermatitis
Term
fleas allergy dermatitis
Definition
most common cause of pyotraumatic dermatitis
Term
1. Flea control
2. Clip hair, clean 2x daily with chlohexidine
3. Temporary symptomatic relief with oral prednisone
4. antihistamines
Definition
tx of pyotraumatic dermatitis
Term
ALL contact dogs must be txed
1. Amitraz, lime sulfur (mitocidal topical therapy) every 3 weeks (only kills adults)
2. Weekly systemic ivermectin (CONTRAINDICATED in herding breeds)
3. weekly milbemycin
4. Selamectin (repeat in 2 weeks)
5. Temp. relief with oral prednisone
6. Topical antipruritic shampoo
Definition
tx of Scabies
Term
3rd stage larvae penetrating skin
Definition
cause of hookworm dermatitis
Term
superficial pyoderma
Definition
most common skin disease in dogs
Term
secondary (due to change in microclimate of skin that allows over growth of Staph pseudointermedius)
Definition
is superficial pyoderma a primary or secondary infection?
Term
1. Chlorhexidine shampoo 2x a week
2. Systemic antibiotics (cephalexin, clavamox)
3. Dx and tx underlying primary disease
4. Avoid systemic steroids
Definition
tx of superficial pyoderma
Term
~3 weeks (1 week past complete clinical resolution)
Definition
how long to treat superficial pyoderma with abx?
Term
no, possibly caused by immune system immaturity
Definition
is there another disease causing puppy pyoderma?
Term
2-9 months
Definition
age of onset for puppy pyoderma
Term
neutrophilic pustules with bacteria
Definition
cytology commonly found with puppy pyoderma
Term
1. May resolve on its own
2. topical antibiotics (few lesions)
3. chlorhexidine shampoo if widespread lesions
4. systemic abx (if widespread, pruritic or persistent)
Definition
tx of puppy pyoderma
Term
nonpruritic
Definition
is puppy pyoderma typically pruritic?
Term
Type II
Definition
type of hypersensitivity associated with pemphigus
Term
pustules containing neutrophils, acantholytic keratinocytes, NO bacteria
Definition
typical cytology of pemphigus foliaceus
Term
hyperkeratotic foot pads (with peeling of footpads)--can be lame on all 4 feet, fever, anorexia, lethargy, can be photoaggravated
Definition
clinical signs of pemphigus foliaceus in dogs and cats
Term
exfoliative dermatitis, coronary band dermatitis, edema of distal limbs, ventral abdomen (due to concurrent vasculitis)
Definition
clinical signs of pemphigus foliaceous in horses
Term
1. immunosppressive therapy (prednisone, azathioprine-NOT CATS!, chlorambucil-cats, Gold Salt therapy)
2. supportive care
3. protection from sunlight
Definition
tx of pemphigus foliaceous
Term
"paint brush" lesions, painful rather than pruritic, thick crusts
Definition
clinical signs associated with Dermatophilosis
Term
dorsum, head & pinnae, distal extremities
Definition
distribution of Dermatophilosis lesions
Term
1. may resolve by itself if kept dry
2. ionophores, chlorhexidine, lime sulfur
3. systemic abx (penicillin)
4. vector control
5. correct poor hygiene
Definition
tx of Dermatophilosis
Term
3-16 wk old puppies
Definition
signalment of juvenile cellulitis
Term
pyogranulomatous inflammation (neutrophils & macrophages) without infectious agent present
Definition
cytology of juvenile cellulitis
Term
acute swilling and surface pustules on muzzle, lips, eyelids; nonpruritic but painful; enlarged submandibular/prescapular lymphnodes; fever, anorexia, depression, joint pain
Definition
clinical signs of juvenile cellulitis
Term
1. systemic steroids (taper quickly)
2. supportive care
3. systemic abx if secondary infection is suspected
Definition
tx of juvenile cellulitis
Term
cat & horse
Definition
mast cell tumors are generally considered benign in which species
Term
oral cavity and nail bed
Definition
where on body do melanocytic tumors have higher rates of malignancy?
Term
hamartoma
Definition
exuberant growth of normal tissue
(ex: nevus)
Term
acrocordon
Definition
medical term for skin tag
Term
panniculitis
Definition
inflammation of subcutaneous fat
Term
infectious, vasculitis,idiopathic
Definition
common causes of panniculitis
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